Chaga · 2023 · Journal Article
Medium relevanceAntifungal Activity of Cadinane-Type Sesquiterpenes from Eupatorium adenophorum against Wood-Decaying Fungi.
Inonotus obliquus
Key points
- The present study aimed to evaluate the antifungal activities of Eupatorium adenophorum against four strains of wood-decaying fungi, including Inonotus hispida, Inonotus obliquus, and Inonotus cuticularis
- Bioguided isolation of the methanol extract of E. adenophorum by silica gel column chromatography and high-performance liquid chromatography afforded six cadinane-type sesquiterpenes
- Their structures were identified by nuclear magnetic resonance and MS analyses
- According to the antifungal results, the inhibition rate of the compound was between 59.85 % and 77.98 % at a concentration of 200 μg/mL. The EC 50 values ranged from 74.5 to 187.4 μg/mL
Metadata-grounded summary
Citation abstract
The present study aimed to evaluate the antifungal activities of Eupatorium adenophorum against four strains of wood-decaying fungi, including Inonotus hispida, Inonotus obliquus, and Inonotus cuticularis. Bioguided isolation of the methanol extract of E. adenophorum by silica gel column chromatography and high-performance liquid chromatography afforded six cadinane-type sesquiterpenes. Their structures were identified by nuclear magnetic resonance and MS analyses. According to the antifungal results, the inhibition rate of the compound was between 59.85 % and 77.98 % at a concentration of 200 μg/mL. The EC 50 values ranged from 74.5 to 187.4 μg/mL.
Citation
Liu Y, Wang D, Hu S, Wu J, Luo J, Cao M, et al. (2023). Antifungal Activity of Cadinane-Type Sesquiterpenes from Eupatorium adenophorum against Wood-Decaying Fungi. Chemistry & biodiversity https://doi.org/10.1002/cbdv.202300879 PMID: 37691010
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