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Reishi, Lingzhi · 2022 · Journal Article

Medium relevance

Mechanism of enhanced production of triterpenoids in algal-fungal consortium.

Ganoderma lucidum

SpeciesReishi, Lingzhi
JournalBioprocess and biosystems engineering
Year2022

Key points

  • Chlorella pyrenoidosa-Ganoderma lucidum symbiotic systems were constructed
  • The mechanism of enhanced production of triterpenoids in algal-fungal consortium by comparing the contents of triterpenoids in individual fungal systems and algal-fungal consortium systems was investigated
  • The production of triterpenoids in C. pyrenoidosa-G. lucidum consortium increased significantly (P 1 and P 1 and P < 0.05) of citrate cycle (TCA cycle), tyrosine metabolism, glycolysis, and terpenoid backbone biosynthesis in algal-fungal consortium were obtained
  • The relative abundances of important precursors of triterpenoids including mevalonic acid, lanosterol, and hydroquinone were 1.4 times, 1.7 times, and 2 times, respectively, in algal-fungal consortium than that in the individual fungal systems
  • The presence of C. pyrenoidosa in algal-fungal consortium promoted the biosynthesis of triterpenoids in G. lucidum

From the paper

Abstract

Chlorella pyrenoidosa-Ganoderma lucidum symbiotic systems were constructed. The mechanism of enhanced production of triterpenoids in algal-fungal consortium by comparing the contents of triterpenoids in individual fungal systems and algal-fungal consortium systems was investigated. The production of triterpenoids in C. pyrenoidosa-G. lucidum consortium increased significantly (P 1 and P 1 and P < 0.05) of citrate cycle (TCA cycle), tyrosine metabolism, glycolysis, and terpenoid backbone biosynthesis in algal-fungal consortium were obtained. The relative abundances of important precursors of triterpenoids including mevalonic acid, lanosterol, and hydroquinone were 1.4 times, 1.7 times, and 2 times, respectively, in algal-fungal consortium than that in the individual fungal systems. The presence of C. pyrenoidosa in algal-fungal consortium promoted the biosynthesis of triterpenoids in G. lucidum.

Citation

Yuan X, Hou M, Ji X, Huang S, Song L, Yu Y, et al. (2022). Mechanism of enhanced production of triterpenoids in algal-fungal consortium. Bioprocess and biosystems engineering https://doi.org/10.1007/s00449-022-02768-y PMID: 35963944

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