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Chaga · 2011 · Journal Article

High relevance

Antiviral activity of Inonotus obliquus fungus extract towards infection caused by hepatitis C virus in cell cultures.

Inonotus obliquus

Metabolic healthLiver supportSkin & hydrationRespiratory
SpeciesChaga
JournalBulletin of experimental biology and medicine
Year2011

Key points

  • Fractions of Inonotus obliquus fungus water extract exhibited a virucidal effect towards hepatitis C virus: it 100-fold reduced its infective properties within 10 min
  • The antiviral effects of fungus extracts manifested after preventive (24 h before infection) and therapeutic use (during infection of porcine embryo kidney cells)
  • Moreover, the data indicate that the birch fungus extracts inhibit production of infective virus by porcine embryo kidney cells

Metadata-grounded summary

Citation abstract

Fractions of Inonotus obliquus fungus water extract exhibited a virucidal effect towards hepatitis C virus: it 100-fold reduced its infective properties within 10 min. The antiviral effects of fungus extracts manifested after preventive (24 h before infection) and therapeutic use (during infection of porcine embryo kidney cells). Moreover, the data indicate that the birch fungus extracts inhibit production of infective virus by porcine embryo kidney cells.

Citation

Shibnev VA, Mishin DV, Garaev TM, Finogenova NP, Botikov AG, Deryabin PG (2011). Antiviral activity of Inonotus obliquus fungus extract towards infection caused by hepatitis C virus in cell cultures. Bulletin of experimental biology and medicine https://doi.org/10.1007/s10517-011-1395-8 PMID: 22462058

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