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Almond Mushroom, ABM · 2023 · Research Support, Non U.S. Gov'T

Low relevance

Validation of agent-based models of surface receptor oligomerisation.

Agaricus blazei

Immune support
SpeciesAlmond Mushroom, ABM
JournalTrends in pharmacological sciences
Year2023

Key points

  • Receptor dimerisation and higher order oligomerisation regulates signalling by a wide variety of transmembrane receptors
  • We discuss how agent-based modelling (ABM) combined with advanced microscopy and structural studies can provide new insights into the regulation of clustering, including spatial considerations, revealing novel targets for therapeutic intervention

Metadata-grounded summary

Citation abstract

Receptor dimerisation and higher order oligomerisation regulates signalling by a wide variety of transmembrane receptors. We discuss how agent-based modelling (ABM) combined with advanced microscopy and structural studies can provide new insights into the regulation of clustering, including spatial considerations, revealing novel targets for therapeutic intervention.

Citation

Clark JC, Watson SP, Owen DM (2023). Validation of agent-based models of surface receptor oligomerisation. Trends in pharmacological sciences https://doi.org/10.1016/j.tips.2023.07.002 PMID: 37507263

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