Mesima, Sanghwang · 2006 · Journal Article
High relevanceTwo novel furan derivatives from Phellinus linteus with anti-complement activity.
Phellinus linteus
Oncology
Key points
- Two novel stereoisomers of furan derivatives, phellinusfurans A (1) and B (2), were isolated from the fruiting body of Phellinus linteus
- Their structures were elucidated by spectroscopic analysis
- Compounds 1 and 2 exhibited significant anti-complement activity with IC50 values of 33.6 and 33.7 microM, respectively, in inhibiting the hemolytic activity of human serum against erythrocytes
Metadata-grounded summary
Citation abstract
Two novel stereoisomers of furan derivatives, phellinusfurans A (1) and B (2), were isolated from the fruiting body of Phellinus linteus. Their structures were elucidated by spectroscopic analysis. Compounds 1 and 2 exhibited significant anti-complement activity with IC50 values of 33.6 and 33.7 microM, respectively, in inhibiting the hemolytic activity of human serum against erythrocytes.
Citation
Min BS, Yun BS, Lee HK, Jung HJ, Jung HA, Choi JS (2006). Two novel furan derivatives from Phellinus linteus with anti-complement activity. Bioorganic & medicinal chemistry letters https://doi.org/10.1016/j.bmcl.2006.03.027 PMID: 16581246
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