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Maitake, Hen of the Woods · 2012 · Research Support, Non U.S. Gov'T

Medium relevance

Isolation, purification and antioxidant activities of polysaccharides from Grifola frondosa.

Grifola frondosa

Immune support
SpeciesMaitake, Hen of the Woods
JournalCarbohydrate polymers
Year2012

Key points

  • The crude polysaccharides (GFP) were isolated from the fruiting bodies of Grifola frondosa and purified by DEAE cellulose-52 chromatography and Sephadex G-100 size-exclusion chromatography in that order
  • Three main fractions, GFP-1, GFP-2 and GFP-3, were obtained through the isolation and purification steps
  • Then the antioxidant activities of these three fractions were investigated in vitro
  • The results showed that GFP-1, GFP-2 and GFP-3 possessed significant inhibitory effects on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, hydroxyl radical and superoxide radical; their reducing power, ferrous ions chelating effect and the inhibition ability of the rat liver lipid oxidation where also strong
  • These results suggest that G. frondosa polysaccharides could be a suitable natural antioxidant and may be the functional foods for humans

Metadata-grounded summary

Citation abstract

The crude polysaccharides (GFP) were isolated from the fruiting bodies of Grifola frondosa and purified by DEAE cellulose-52 chromatography and Sephadex G-100 size-exclusion chromatography in that order. Three main fractions, GFP-1, GFP-2 and GFP-3, were obtained through the isolation and purification steps. Then the antioxidant activities of these three fractions were investigated in vitro. The results showed that GFP-1, GFP-2 and GFP-3 possessed significant inhibitory effects on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, hydroxyl radical and superoxide radical; their reducing power, ferrous ions chelating effect and the inhibition ability of the rat liver lipid oxidation where also strong. These results suggest that G. frondosa polysaccharides could be a suitable natural antioxidant and may be the functional foods for humans.

Citation

Chen GT, Ma XM, Liu ST, Liao YL, Zhao GQ (2012). Isolation, purification and antioxidant activities of polysaccharides from Grifola frondosa. Carbohydrate polymers https://doi.org/10.1016/j.carbpol.2012.02.045 PMID: 24750604

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