Structural investigation of a novel rhamnoglucogalactan isolated from the fruiting bodies of the fungus Hericium erinaceus.

Hericium erinaceus

Cognition & nerves

SpeciesLion's Mane, Yamabushitake

JournalCarbohydrate research

Year2004

Key points

A new heteropolysaccharide (HEP-1) was isolated from the fruiting bodies of Hericium erinaceus
It was estimated to have a molecular weight of 1.8x10(4) da and showed [alpha](D)(20) +129 (c 0.295, H(2)O)
HEP-1 is composed of rhamnose, galactose, and glucose in the ratio of 1.19:3.81:1.00
Its structural features were investigated using composition analysis, methylation analysis, partial hydrolysis, and IR and NMR spectroscopy
The results showed that HEP-1 has a (1-->6)-linked alpha-d-galactopyranosyl backbone with branches that are composed of rhamnose and glucose attached to O-2

Metadata-grounded summary

Citation abstract

A new heteropolysaccharide (HEP-1) was isolated from the fruiting bodies of Hericium erinaceus. It was estimated to have a molecular weight of 1.8x10(4) da and showed [alpha](D)(20) +129 (c 0.295, H(2)O). HEP-1 is composed of rhamnose, galactose, and glucose in the ratio of 1.19:3.81:1.00. Its structural features were investigated using composition analysis, methylation analysis, partial hydrolysis, and IR and NMR spectroscopy. The results showed that HEP-1 has a (1-->6)-linked alpha-d-galactopyranosyl backbone with branches that are composed of rhamnose and glucose attached to O-2.

Citation

Jia LM, Liu L, Dong Q, Fang JN (2004). Structural investigation of a novel rhamnoglucogalactan isolated from the fruiting bodies of the fungus Hericium erinaceus. Carbohydrate research https://doi.org/10.1016/j.carres.2004.07.027 PMID: 15519325

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