Anti-inflammatory and immunomodulatory properties of polysaccharides in mushrooms.

Lentinula edodes

Immune supportGut & microbiome

SpeciesShiitake, Hua Gu

JournalCurrent opinion in biotechnology

Year2024

Key points

Mushrooms are distinguished as important food-containing polysaccharides possessing potent anti-inflammatory and immunomodulating properties
These compounds belong mostly to polysaccharides that are mostly β-D-glucans
Among them, β-1,3-glucan with β-1,6 side chains of glucose residues, has more important roles in their properties
In this review, we have introduced polysaccharides mainly from Lentinula edodes and Pleurotus citrinopileatus with anti-inflammatory and immunomodulating properties
In addition, the mechanisms of activation of their physiological properties and signal cascade are also reviewed

Metadata-grounded summary

Citation abstract

Mushrooms are distinguished as important food-containing polysaccharides possessing potent anti-inflammatory and immunomodulating properties. These compounds belong mostly to polysaccharides that are mostly β-D-glucans. Among them, β-1,3-glucan with β-1,6 side chains of glucose residues, has more important roles in their properties. In this review, we have introduced polysaccharides mainly from Lentinula edodes and Pleurotus citrinopileatus with anti-inflammatory and immunomodulating properties. In addition, the mechanisms of activation of their physiological properties and signal cascade are also reviewed.

Citation

Mizuno M, Minato KI (2024). Anti-inflammatory and immunomodulatory properties of polysaccharides in mushrooms. Current opinion in biotechnology https://doi.org/10.1016/j.copbio.2024.103076 PMID: 38364705

Open citation