Niu-Chang-Chih · 2015 · Journal Article
High relevanceAnti-cancer agents derived from solid-state fermented Antrodia camphorata mycelium.
Antrodia camphorata
Key points
- Three new ubiquinone derivatives, antrocamol LT1, antrocamol LT2, and antrocamol LT3, along with two known compounds, were isolated from Antrodia camphorata (Polyporaceae) mycelium
- The structures of these compounds were established on the basis of extensive 1D and 2D NMR spectroscopic analyses
- These ubiquinones exhibited selective cytotoxicities against five human cancer cell lines (CT26, A549, HepG2, PC3 and DU-145) with IC50 values ranging from 0.01 to 1.79μΜ
Metadata-grounded summary
Citation abstract
Three new ubiquinone derivatives, antrocamol LT1, antrocamol LT2, and antrocamol LT3, along with two known compounds, were isolated from Antrodia camphorata (Polyporaceae) mycelium. The structures of these compounds were established on the basis of extensive 1D and 2D NMR spectroscopic analyses. These ubiquinones exhibited selective cytotoxicities against five human cancer cell lines (CT26, A549, HepG2, PC3 and DU-145) with IC50 values ranging from 0.01 to 1.79μΜ.
Citation
Yen IC, Yao CW, Kuo MT, Chao CL, Pai CY, Chang WL (2015). Anti-cancer agents derived from solid-state fermented Antrodia camphorata mycelium. Fitoterapia https://doi.org/10.1016/j.fitote.2015.02.010 PMID: 25721423
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