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Nameko, Nametake · 2012 · Research Support, Non U.S. Gov'T

Medium relevance

Effects of the polysaccharide from Pholiota nameko on human cytokine network in serum.

Pholiota microspora

Immune support
SpeciesNameko, Nametake
JournalInternational journal of biological macromolecules
Year2012

Key points

  • Some physico-chemical characterizations of Pholiota nameko polysaccharides (PNPS-1) were studied, including sulfate content, UV/visible and infrared spectra, also the variation of cytokine communication network in serum to clarify the pharmacological effects of PNPS-1 by determination of 39 cytokines in serum of healthy volunteers
  • The result proved that PNPS-1 possessed significant anti-inflammatory activity
  • Further, we use Microsoft Visio 2007 software to map out the cell-cell communication network diagram
  • The analysis to the diagram suggested that PNPS-1 could take effect on the innate and adaptive immunity and hematopoiesis of volunteers

Metadata-grounded summary

Citation abstract

Some physico-chemical characterizations of Pholiota nameko polysaccharides (PNPS-1) were studied, including sulfate content, UV/visible and infrared spectra, also the variation of cytokine communication network in serum to clarify the pharmacological effects of PNPS-1 by determination of 39 cytokines in serum of healthy volunteers. The result proved that PNPS-1 possessed significant anti-inflammatory activity. Further, we use Microsoft Visio 2007 software to map out the cell-cell communication network diagram. The analysis to the diagram suggested that PNPS-1 could take effect on the innate and adaptive immunity and hematopoiesis of volunteers.

Citation

Li H, Liu X, Li Y, Hua Y, Zhi D, Pang G (2012). Effects of the polysaccharide from Pholiota nameko on human cytokine network in serum. International journal of biological macromolecules https://doi.org/10.1016/j.ijbiomac.2011.10.015 PMID: 22044749

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