King Oyster, Eryngii · 2012 · Journal Article
High relevanceOptimization of extracellular glucan production from Pleurotus eryngii and its impact on angiogenesis.
Pleurotus eryngii
Key points
- Pleurotus eryngii, an edible mushroom with therapeutic potential was optimized using response surface methodology of four-factor Box-Behnken design for maximum mycelial biomass and extracellular glucan (EPS) production
- The model predicts to gain a maximal mycelial biomass and extracellular polysaccharide at 39.4 g/l; 36.04 g/l of glucose, 8.27 g/l; 7.51 g/l of yeast extract, pH 6.99; 7.07 and temperature 26.2°C; 25.84°C, respectively
- The validation experiments showed that the model was significant and in close agreement with the model prediction
- The evaluation of extracellular polysaccharide on angiogenesis by ex vivo CAM assay showed that there was significant inhibition in neo-vascularization
Metadata-grounded summary
Citation abstract
Pleurotus eryngii, an edible mushroom with therapeutic potential was optimized using response surface methodology of four-factor Box-Behnken design for maximum mycelial biomass and extracellular glucan (EPS) production. The model predicts to gain a maximal mycelial biomass and extracellular polysaccharide at 39.4 g/l; 36.04 g/l of glucose, 8.27 g/l; 7.51 g/l of yeast extract, pH 6.99; 7.07 and temperature 26.2°C; 25.84°C, respectively. The validation experiments showed that the model was significant and in close agreement with the model prediction. The evaluation of extracellular polysaccharide on angiogenesis by ex vivo CAM assay showed that there was significant inhibition in neo-vascularization.
Citation
Shenbhagaraman R, Jagadish LK, Premalatha K, Kaviyarasan V (2012). Optimization of extracellular glucan production from Pleurotus eryngii and its impact on angiogenesis. International journal of biological macromolecules https://doi.org/10.1016/j.ijbiomac.2012.02.008 PMID: 22361455
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