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Chaga · 2013 · Research Support, Non U.S. Gov'T

Medium relevance

Chemical analysis and antioxidant activity of polysaccharides extracted from Inonotus obliquus sclerotia.

Inonotus obliquus

Immune supportMetabolic healthSkin & hydration
SpeciesChaga
JournalInternational journal of biological macromolecules
Year2013

Key points

  • Three water-soluble polysaccharide fractions (IOP40, IOP60 and IOP80) were isolated by using different concentrations of alcohol precipitation from Inonotus obliquus sclerotia
  • Their physicochemical properties, including total sugar content, protein content, monosaccharide composition and percentage were analyzed
  • And their in vitro antioxidant capacities were investigated in terms of reducing power assay and scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals, hydroxyl radicals, superoxide anion radicals and hydrogen peroxide (H2O2)
  • In general, three polysaccharide fractions exhibited increasing antioxidant activity with increasing concentration at the ranges of tested dosage
  • The orders of reducing power, DPPH-scavenging capacity, H2O2-scavenging capacity, and hydroxyl-scavenging activity were all IOP60>IOP40>IOP80
  • These findings demonstrated that three polysaccharide fractions extracted from I. obliquus, especially IOP60, could be employed as natural ingredients in functional food and pharmaceutical industry to alleviate the oxidative stress

Metadata-grounded summary

Citation abstract

Three water-soluble polysaccharide fractions (IOP40, IOP60 and IOP80) were isolated by using different concentrations of alcohol precipitation from Inonotus obliquus sclerotia. Their physicochemical properties, including total sugar content, protein content, monosaccharide composition and percentage were analyzed. And their in vitro antioxidant capacities were investigated in terms of reducing power assay and scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals, hydroxyl radicals, superoxide anion radicals and hydrogen peroxide (H2O2). In general, three polysaccharide fractions exhibited increasing antioxidant activity with increasing concentration at the ranges of tested dosage. The orders of reducing power, DPPH-scavenging capacity, H2O2-scavenging capacity, and hydroxyl-scavenging activity were all IOP60>IOP40>IOP80. These findings demonstrated that three polysaccharide fractions extracted from I. obliquus, especially IOP60, could be employed as natural ingredients in functional food and pharmaceutical industry to alleviate the oxidative stress.

Citation

Du X, Mu H, Zhou S, Zhang Y, Zhu X (2013). Chemical analysis and antioxidant activity of polysaccharides extracted from Inonotus obliquus sclerotia. International journal of biological macromolecules https://doi.org/10.1016/j.ijbiomac.2013.10.016 PMID: 24145301

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