Simple and efficient isolation of cordycepin from culture broth of a Cordyceps militaris mutant.

Cordyceps militaris

SpeciesCordyceps, Scarlet Club

JournalJournal of bioscience and bioengineering

Year2015

Key points

Isolation of cordycepin from the culture broth of Cordyceps militaris mutant was investigated
Based on the solubility curve, three crystallizing processes, temperature shift (process I), pH shift (process II), and pH shift followed by temperature shift (process III) were carried out
Process III was the most promising method regarding both purity and yield

From the paper

Abstract

Isolation of cordycepin from the culture broth of Cordyceps militaris mutant was investigated. Based on the solubility curve, three crystallizing processes, temperature shift (process I), pH shift (process II), and pH shift followed by temperature shift (process III) were carried out. Process III was the most promising method regarding both purity and yield.

Citation

Masuda M, Hatashita M, Fujihara S, Suzuki Y, Sakurai A (2015). Simple and efficient isolation of cordycepin from culture broth of a Cordyceps militaris mutant. Journal of bioscience and bioengineering https://doi.org/10.1016/j.jbiosc.2015.04.008 PMID: 26100320

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