Zhu Ling, Umbrella Polypore · 2023 · Research Support, Non U.S. Gov'T
High relevanceS-o-(p-Methoxyphenylethynyl)benzyl (SMPEB) Glycosides for Catalytic Glycosylation and Their Application in the Synthesis of Polyporus Umbellatus Polysaccharides.
Polyporus umbellatus
Key points
- We herein reported a new type of S - o -( p -methoxyphenylethynyl)benzyl donor for a highly efficient glycosylation method
- The donor was activated by 10% Tf 2 O and underwent glycosylation with various acceptors to provide the corresponding glycosides in excellent yield
- Furthermore, two repetitive fragments of Polyporus umbellatus polysaccharides (PUPs), isolated from traditional Chinese medicine " Polyporus umbellatus ", were prepared by combining the "single-catalyst one-pot" and "latent-active" strategies for the first time for future clear studies on the structure-activity relationship of PUPs
Metadata-grounded summary
Citation abstract
We herein reported a new type of S - o -( p -methoxyphenylethynyl)benzyl donor for a highly efficient glycosylation method. The donor was activated by 10% Tf 2 O and underwent glycosylation with various acceptors to provide the corresponding glycosides in excellent yield. Furthermore, two repetitive fragments of Polyporus umbellatus polysaccharides (PUPs), isolated from traditional Chinese medicine " Polyporus umbellatus ", were prepared by combining the "single-catalyst one-pot" and "latent-active" strategies for the first time for future clear studies on the structure-activity relationship of PUPs.
Citation
Wang J, Lan X, Zhang S, Cai C, Zhang Q, Feng Y, et al. (2023). S-o-(p-Methoxyphenylethynyl)benzyl (SMPEB) Glycosides for Catalytic Glycosylation and Their Application in the Synthesis of Polyporus Umbellatus Polysaccharides. Organic letters https://doi.org/10.1021/acs.orglett.3c02072 PMID: 37578318
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