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King Oyster, Eryngii · 2014 · Research Support, Non U.S. Gov'T

High relevance

Changes in chemical components and cytotoxicity at different maturity stages of Pleurotus eryngii fruiting body.

Pleurotus eryngii

OncologyImmune support
SpeciesKing Oyster, Eryngii
JournalJournal of agricultural and food chemistry
Year2014

Key points

  • The present study investigated the changes of the chemical components and cytotoxicity potency at 5 developmental stages of Pleurotus eryngii fruiting body
  • The carbohydrate and protein contents increased along the maturity of fruiting body while fat content decreased
  • By comparison, the polysaccharide-protein fractions had the highest antiproliferative effect on SGC-7901 and HepG-2 cells in vitro and increasing activity with growing maturity of P. eryngii fruiting body.The maturation process increased the protein content and acid property through the enhanced relative abundance of Asp, Thr, and Glu in polysaccharide-protein fractions
  • Further purification and electrophoresis identified that the polysaccharide-protein PEG-1with three subunits possibly was the target cytotoxical component
  • Our findings proved that mature fruiting body of P. eryngii containing these polysaccharide-proteins possessed highly nutritional values and therapeutical benefits

From the paper

Abstract

The present study investigated the changes of the chemical components and cytotoxicity potency at 5 developmental stages of Pleurotus eryngii fruiting body. The carbohydrate and protein contents increased along the maturity of fruiting body while fat content decreased. By comparison, the polysaccharide-protein fractions had the highest antiproliferative effect on SGC-7901 and HepG-2 cells in vitro and increasing activity with growing maturity of P. eryngii fruiting body.The maturation process increased the protein content and acid property through the enhanced relative abundance of Asp, Thr, and Glu in polysaccharide-protein fractions. Further purification and electrophoresis identified that the polysaccharide-protein PEG-1with three subunits possibly was the target cytotoxical component. Our findings proved that mature fruiting body of P. eryngii containing these polysaccharide-proteins possessed highly nutritional values and therapeutical benefits.

Citation

Cui F, Li Y, Yang Y, Sun W, Wu D, Ping L (2014). Changes in chemical components and cytotoxicity at different maturity stages of Pleurotus eryngii fruiting body. Journal of agricultural and food chemistry https://doi.org/10.1021/jf5048354 PMID: 25483207

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