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Lion's Mane, Yamabushitake · 2015 · Research Support, Non U.S. Gov'T

Medium relevance

Erinaceolactones A to C, from the culture broth of Hericium erinaceus.

Hericium erinaceus

Cognition & nerves
SpeciesLion's Mane, Yamabushitake
JournalJournal of natural products
Year2015

Key points

  • Three novel compounds, erinaceolactones A to C (1-3), and a known compound (4) were isolated from the culture broth of Hericium erinaceus
  • The planar structures of 1-3 were determined by the interpretation of spectroscopic data
  • The absolute configuration of 3 was determined by X-ray crystallography
  • Although compound 4 had been synthesized, it was isolated from a natural source for the first time
  • In the bioassay examining plant-growth regulatory activity of these compounds (1-4) and other components of the fungus (5-8), compounds 1, 2, and 4-8 suppressed the growth of lettuce

Metadata-grounded summary

Citation abstract

Three novel compounds, erinaceolactones A to C (1-3), and a known compound (4) were isolated from the culture broth of Hericium erinaceus. The planar structures of 1-3 were determined by the interpretation of spectroscopic data. The absolute configuration of 3 was determined by X-ray crystallography. Although compound 4 had been synthesized, it was isolated from a natural source for the first time. In the bioassay examining plant-growth regulatory activity of these compounds (1-4) and other components of the fungus (5-8), compounds 1, 2, and 4-8 suppressed the growth of lettuce.

Citation

Wu J, Tokunaga T, Kondo M, Ishigami K, Tokuyama S, Suzuki T, et al. (2015). Erinaceolactones A to C, from the culture broth of Hericium erinaceus. Journal of natural products https://doi.org/10.1021/np500623s PMID: 25534373

Open citation