Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T
Low relevanceFirst total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents.
Antrodia camphorata
Key points
- Naturally occurring antrocamphin A (1) is a potent anti-inflammatory compound from the edible fungus Antrodia camphorata (Taiwanofungus camphoratus), whose wild fruiting body is used as a valuable folk medicine in Taiwan
- This study is the first total synthesis of antrocamphin A (1) and its analogs
- Their inhibition ability on NO release, superoxide anion generation, elastase release and platelet aggregation are reported herein
Metadata-grounded summary
Citation abstract
Naturally occurring antrocamphin A (1) is a potent anti-inflammatory compound from the edible fungus Antrodia camphorata (Taiwanofungus camphoratus), whose wild fruiting body is used as a valuable folk medicine in Taiwan. This study is the first total synthesis of antrocamphin A (1) and its analogs. Their inhibition ability on NO release, superoxide anion generation, elastase release and platelet aggregation are reported herein.
Citation
Lee CL, Huang CH, Wang HC, Chuang DW, Wu MJ, Wang SY, et al. (2011). First total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents. Organic & biomolecular chemistry https://doi.org/10.1039/c0ob00616e PMID: 21088769
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