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Wood Ear, Kikurage · 2019 · Journal Article

High relevance

The medicinal mushroom Auricularia auricula-judae (Bull.) extract has antioxidant activity and promotes procollagen biosynthesis in HaCaT cells.

Auricularia auricula-judae

Skin & hydration
SpeciesWood Ear, Kikurage
JournalNatural product research
Year2019

Key points

  • In this study, Auricularia auricula - judae (Bull.) extract (AAE) had potent antioxidant activity in vitro and promoted the biosynthesis of procollagen, a precursor of collagen in HaCaT cells
  • In addition, the expression of HAS - 3 (hyaluronic acid synthase), which is a moisturizing factor, was increased in HaCaT cells in response to AAE. Therefore, this work suggests that AAE has the potential to exhibit antioxidant activity and promote procollagen biosynthesis in HaCaT cells

Metadata-grounded summary

Citation abstract

In this study, Auricularia auricula - judae (Bull.) extract (AAE) had potent antioxidant activity in vitro and promoted the biosynthesis of procollagen, a precursor of collagen in HaCaT cells. In addition, the expression of HAS - 3 (hyaluronic acid synthase), which is a moisturizing factor, was increased in HaCaT cells in response to AAE. Therefore, this work suggests that AAE has the potential to exhibit antioxidant activity and promote procollagen biosynthesis in HaCaT cells.

Citation

Choi YJ, Park IS, Kim MH, Kwon B, Choo YM, Jeong SI, et al. (2019). The medicinal mushroom Auricularia auricula-judae (Bull.) extract has antioxidant activity and promotes procollagen biosynthesis in HaCaT cells. Natural product research https://doi.org/10.1080/14786419.2018.1468332 PMID: 29726712

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