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Chaga · 2021 · Journal Article

High relevance

Aromatic compounds from the sclerotia of Inonotus obliquus.

Inonotus obliquus

Metabolic healthSkin & hydration
SpeciesChaga
JournalNatural product research
Year2021

Key points

  • Three new aromatic compounds ( 1a / 1b, 2 ) including a pair of enantiomers ( 1a / 1b ), were isolated from Inonotus obliquus
  • The structures of the new compounds were elucidated by extensive spectroscopic analyses, and the absolute configurations of 1a and 1b were determined by electronic circular dichroism (ECD) calculated
  • All isolates were evaluated for their cytotoxic activities against Hep3B and HepG2 cell lines
  • Compounds 1b and 2 showed weak cytotoxicity toward the Hep3B cells at 25 μM

Metadata-grounded summary

Citation abstract

Three new aromatic compounds ( 1a / 1b, 2 ) including a pair of enantiomers ( 1a / 1b ), were isolated from Inonotus obliquus. The structures of the new compounds were elucidated by extensive spectroscopic analyses, and the absolute configurations of 1a and 1b were determined by electronic circular dichroism (ECD) calculated. All isolates were evaluated for their cytotoxic activities against Hep3B and HepG2 cell lines. Compounds 1b and 2 showed weak cytotoxicity toward the Hep3B cells at 25 μM.

Citation

Zou CX, Zhang YY, Bai M, Huang XX, Wang XB, Song SJ (2021). Aromatic compounds from the sclerotia of Inonotus obliquus. Natural product research https://doi.org/10.1080/14786419.2019.1677656 PMID: 31612726

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