Chaga · 2022 · Journal Article
High relevancePhenolic compounds from the sclerotia of Inonotus obliquus.
Inonotus obliquus
Cognition & nerves
Key points
- Three phenolic compounds (±1 and 2) including a pair of new enantiomers were isolated from the sclerotia of Inonotus obliquus
- Their structures were assigned by extensive spectroscopic analyses
- All the compounds were evaluated for the neuroprotective activity against oxidative damage on human neuroblastoma SH-SY5Y cells induced by H2O2
- Compound 2 showed remarkable neuroprotective effect and significantly improved the cell viability of SH-SY5Y cells treated by H2O2
From the paper
Abstract
Three phenolic compounds (±1 and 2) including a pair of new enantiomers were isolated from the sclerotia of Inonotus obliquus. Their structures were assigned by extensive spectroscopic analyses. All the compounds were evaluated for the neuroprotective activity against oxidative damage on human neuroblastoma SH-SY5Y cells induced by H2O2. Compound 2 showed remarkable neuroprotective effect and significantly improved the cell viability of SH-SY5Y cells treated by H2O2.
Citation
Wei YM, Yang L, Mei WL, Chen HQ, Cai CH, Li W, et al. (2022). Phenolic compounds from the sclerotia of Inonotus obliquus. Natural product research https://doi.org/10.1080/14786419.2020.1833202 PMID: 33084385
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