Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii.

Pleurotus eryngii

Gut & microbiomeLiver support

SpeciesKing Oyster, Eryngii

JournalNatural product communications

Year2012

Key points

Ergosterol peroxide was isolated from the ethanol extract of Pleurotus eryngii as an inhibitor of osteoclast differentiation
This compound showed an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 microg/mL

Metadata-grounded summary

Citation abstract

Ergosterol peroxide was isolated from the ethanol extract of Pleurotus eryngii as an inhibitor of osteoclast differentiation. This compound showed an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 microg/mL.

Citation

Yokoyama S, Bang TH, Shimizu K, Kondo R (2012). Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii. Natural product communications https://doi.org/10.1177/1934578x1200700913 PMID: 23074896

Open citation