Cordyceps, Caterpillar Fungus · 2007 · Journal Article
Medium relevanceNew Diphenyl Ethers from the Insect Pathogenic Fungus Cordyceps sp. BCC 1861
Ophiocordyceps sinensis
Key points
- Two novel diphenyl ether glycosides and a new diphenyl ether, cordyol A-C (1-3), were isolated from the insect pathogenic fungus Cordyceps sp
- Structures of these compounds were elucidated by NMR and MS spectral analyses
- Cordyol C (3) exhibited significant anti-HSV-1 activity with an IC50 value of 1.3 microg/ml, and cytotoxic activity against BC and NCI-H187 cancer cell lines with IC50 values of 8.65 and 3.72 microg/ml, respectively
- Cordyol A (1) displayed weak antimycobacterial activity with a MIC value of 100 microg/ml
From the paper
Abstract
Two novel diphenyl ether glycosides and a new diphenyl ether, cordyol A-C (1-3), were isolated from the insect pathogenic fungus Cordyceps sp. BCC 1861. Structures of these compounds were elucidated by NMR and MS spectral analyses. Cordyol C (3) exhibited significant anti-HSV-1 activity with an IC50 value of 1.3 microg/ml, and cytotoxic activity against BC and NCI-H187 cancer cell lines with IC50 values of 8.65 and 3.72 microg/ml, respectively. Cordyol A (1) displayed weak antimycobacterial activity with a MIC value of 100 microg/ml.
Citation
Taridaporn Bunyapaiboonsri Seangaroon Yoiprommarat Kamolphan Intereya Kanokarn Kocharin (2007). New Diphenyl Ethers from the Insect Pathogenic Fungus Cordyceps sp. BCC 1861. Chemical and Pharmaceutical Bulletin https://doi.org/10.1248/cpb.55.304
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