Cordyceps, Caterpillar Fungus · 1996 · Journal Article
Low relevanceEffects of the Mycelial Extract of Cultured Cordyceps Sinensis on In Vivo Hepatic Energy Metabolism in the Mouse
Ophiocordyceps sinensis
Key points
- Mice were given the extract of cultured Cordyceps sinensis (Cs) (200 mg/kg daily, p.o.) for 3 weeks
- In vivo phosphorus-31 nuclear magnetic resonance (NMR) spectra of the liver were acquired at weekly intervals using a surface coil
- From 1 to 3 weeks, a consistent increase in the ATP/inorganic phosphate ratio, which represents the high energy state, was observed in the Cs extract-treated mice
- The intracellular pH of the Cs extract-treated mice was not significantly different from that of the control mice
- No steatosis, necrosis, inflammation or fibrosis were observed in the liver specimens from Cs extract-treated mice
From the paper
Abstract
Mice were given the extract of cultured Cordyceps sinensis (Cs) (200 mg/kg daily, p.o.) for 3 weeks. In vivo phosphorus-31 nuclear magnetic resonance (NMR) spectra of the liver were acquired at weekly intervals using a surface coil. From 1 to 3 weeks, a consistent increase in the ATP/inorganic phosphate ratio, which represents the high energy state, was observed in the Cs extract-treated mice. The intracellular pH of the Cs extract-treated mice was not significantly different from that of the control mice. No steatosis, necrosis, inflammation or fibrosis were observed in the liver specimens from Cs extract-treated mice.
Citation
Noboru Manabe Miki Sugimoto Yasuyoshi Azuma Naoki Taketomo Akio Yamashita Hiroshi Tsuboi Akinobu Tsunoo Noriko Kinjo Huang Nian-Lai Hajime Miyamoto (1996). Effects of the Mycelial Extract of Cultured Cordyceps Sinensis on In Vivo Hepatic Energy Metabolism in the Mouse. The Japanese Journal of Pharmacology https://doi.org/10.1254/jjp.70.85
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