Reishi, Lingzhi · 2011 · Journal Article
Medium relevanceGanodermasides C and D, Two New Anti-Aging Ergosterols from Spores of the Medicinal Mushroom Ganoderma lucidum
Ganoderma lucidum
Key points
- Two new anti-aging compounds, ganodermasides C and D, were isolated and their structures elucidated
- They are novel ergosterols possessing a 4,6,8(14),22-tetraene-3-one unit with unique hydroxylation at C-9
- Both of them significantly extended the replicative lifespan of the K6001 yeast strain
- Ganodermasides C and D regulated the expression of the gene for UTH1 to prolong the replicative lifespan of yeast
From the paper
Abstract
Two new anti-aging compounds, ganodermasides C and D, were isolated and their structures elucidated. They are novel ergosterols possessing a 4,6,8(14),22-tetraene-3-one unit with unique hydroxylation at C-9. Both of them significantly extended the replicative lifespan of the K6001 yeast strain. Ganodermasides C and D regulated the expression of the gene for UTH1 to prolong the replicative lifespan of yeast.
Citation
Yufang WENG Jun LU Lan XIANG Akira MATSUURA Yang ZHANG Qianming HUANG Jianhua QI (2011). Ganodermasides C and D, Two New Anti-Aging Ergosterols from Spores of the Medicinal Mushroom Ganoderma lucidum. Bioscience, Biotechnology, and Biochemistry https://doi.org/10.1271/bbb.100918
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