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Maitake, Hen of the Woods · 2000 · Journal Article

Low relevance

Suppression of D-Galactosamine-induced Liver Injury by Mushrooms in Rats

Grifola frondosa

Immune supportLiver support
SpeciesMaitake, Hen of the Woods
JournalBioscience, biotechnology, and biochemistry
Year2000

Key points

  • Six species of edible mushroom were found to suppress D-galactosamine-induced enhancement of plasma alanine and aspartate aminotransferase activities when powdered mushrooms were added to the diet (5%) and fed to rats for 2 wk
  • Grifola frondosa exhibited the most potent effect in a dose-dependent manner
  • A significant effect was observed only from the water-soluble low-molecular-weight fraction of G. frondosa
  • The results indicate that several mushrooms possess a protective effect against liver injury induced by D-galactosamine

Metadata-grounded summary

Citation abstract

Six species of edible mushroom were found to suppress D-galactosamine-induced enhancement of plasma alanine and aspartate aminotransferase activities when powdered mushrooms were added to the diet (5%) and fed to rats for 2 wk. Grifola frondosa exhibited the most potent effect in a dose-dependent manner. A significant effect was observed only from the water-soluble low-molecular-weight fraction of G. frondosa. The results indicate that several mushrooms possess a protective effect against liver injury induced by D-galactosamine.

Citation

Lee EW, He P, Kawagishi H, Sugiyama K (2000). Suppression of D-Galactosamine-induced Liver Injury by Mushrooms in Rats. Bioscience, biotechnology, and biochemistry https://doi.org/10.1271/bbb.64.2001 PMID: 11055413

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