Inhibition by Agaricus blazei Murill Fractions of Cytopathic Effect Induced by Western Equine Encephalitis (WEE) Virus on VERO Cells in Vitro

Agaricus blazei

Respiratory

SpeciesAlmond Mushroom, ABM

JournalBioscience, Biotechnology, and Biochemistry

Year2001

Key points

Anti-viral activities of Agaricus blazei Murill were investigated
The water extracts of the cultured mycelia and fruiting bodies were fractionated with different concentrations of ethanol
To several viruses which have cytopathic effects (CPE) on VERO cells, inhibition of these effects by the ethanol fractions was tested
Strong inhibition of CPE induced by western equine encephalitis (WEE) virus was observed in the mycelial fractions but not those of fruiting bodies

From the paper

Abstract

Anti-viral activities of Agaricus blazei Murill were investigated. The water extracts of the cultured mycelia and fruiting bodies were fractionated with different concentrations of ethanol. To several viruses which have cytopathic effects (CPE) on VERO cells, inhibition of these effects by the ethanol fractions was tested. Strong inhibition of CPE induced by western equine encephalitis (WEE) virus was observed in the mycelial fractions but not those of fruiting bodies.

Citation

Kenji SORIMACHI Yukari IKEHARA Genzo MAEZATO Akira OKUBO Sunao YAMAZAKI Kazumi AKIMOTO Akira NIWA (2001). Inhibition by Agaricus blazei Murill Fractions of Cytopathic Effect Induced by Western Equine Encephalitis (WEE) Virus on VERO Cells in Vitro. Bioscience, Biotechnology, and Biochemistry https://doi.org/10.1271/bbb.65.1645

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