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Maitake, Hen of the Woods · 2004 · Case Reports

High relevance

Successful Treatment of Hypersensitivity Pneumonitis Caused by Grifola frondosa (Maitake) Mushroom Using a HFA-BDP Extra-fine Aerosol

Grifola frondosa

Immune support
SpeciesMaitake, Hen of the Woods
JournalInternal medicine (Tokyo, Japan)
Year2004

Key points

  • We successfully treated a patient with occupational hypersensitivity pneumonitis (HP) caused by Grifola frondosa (Maitake) mushroom spore with an extra-fine aerosol corticosteroid; beclomethasone dipropionate (BDP) dissolved in hydrofluoroalkane-134a (HFA)
  • A 49-year-old woman developed respiratory symptoms 3 months after beginning work on a mushroom farm
  • She was diagnosed as HP based on radiological and serological findings
  • Oral prednisolone therapy improved her HP and she returned to the same farm
  • Her HP relapsed after 5 months, and daily 400 microg of HFA-BDP was administered with gradual improvement
  • An extra-fine particle inhaled corticosteroid might reach appropriate alveoli to be effective therapy for mild HP

Metadata-grounded summary

Citation abstract

We successfully treated a patient with occupational hypersensitivity pneumonitis (HP) caused by Grifola frondosa (Maitake) mushroom spore with an extra-fine aerosol corticosteroid; beclomethasone dipropionate (BDP) dissolved in hydrofluoroalkane-134a (HFA). A 49-year-old woman developed respiratory symptoms 3 months after beginning work on a mushroom farm. She was diagnosed as HP based on radiological and serological findings. Oral prednisolone therapy improved her HP and she returned to the same farm. Her HP relapsed after 5 months, and daily 400 microg of HFA-BDP was administered with gradual improvement. An extra-fine particle inhaled corticosteroid might reach appropriate alveoli to be effective therapy for mild HP.

Citation

Tanaka H, Tsunematsu K, Nakamura N, Suzuki K, Tanaka N, Takeya I, et al. (2004). Successful Treatment of Hypersensitivity Pneumonitis Caused by Grifola frondosa (Maitake) Mushroom Using a HFA-BDP Extra-fine Aerosol. Internal medicine (Tokyo, Japan) https://doi.org/10.2169/internalmedicine.43.737 PMID: 15468977

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