Immunomodulating compounds in Basidiomycetes

Lentinula edodes

OncologyImmune supportMetabolic health

SpeciesShiitake, Hua Gu

JournalJournal of Clinical Biochemistry and Nutrition

Year2013

Key points

Mushrooms are distinguished as important food containing immunomodulating and anticancer agents
These compounds belong mostly to polysaccharides especially β-d-glucans
Among them, β-1,3-glucan with side chain β-1,6-glucose residues have more important roles in immunomodulating and antitumor activities
In this review, we have introduced polysaccharide mainly from Lentinula edodes and Agaricus blazei Murill with immunomodulating and antitumor activities
In addition, the mechanism of activation of immune response and signal cascade are also reviewed

From the paper

Abstract

Mushrooms are distinguished as important food containing immunomodulating and anticancer agents. These compounds belong mostly to polysaccharides especially β-d-glucans. Among them, β-1,3-glucan with side chain β-1,6-glucose residues have more important roles in immunomodulating and antitumor activities. In this review, we have introduced polysaccharide mainly from Lentinula edodes and Agaricus blazei Murill with immunomodulating and antitumor activities. In addition, the mechanism of activation of immune response and signal cascade are also reviewed.

Citation

Masashi Mizuno Yosuke Nishitani (2013). Immunomodulating compounds in Basidiomycetes. Journal of Clinical Biochemistry and Nutrition https://doi.org/10.3164/jcbn.13-3

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