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Niu-Chang-Chih · 2012 · Research Support, Non U.S. Gov'T

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An efficient total synthesis of a potent anti-inflammatory agent, benzocamphorin F, and its anti-inflammatory activity.

Antrodia camphorata

OncologyCognition & nervesLiver support
SpeciesNiu-Chang-Chih
JournalInternational journal of molecular sciences
Year2012

Key points

  • A naturally occurring enynyl-benzenoid, benzocamphorin F (1), from the edible fungus Taiwanofungus camphoratus (Antrodia camphorata) was characterized by comprehensive spectral analysis
  • It displays anti-inflammatory bioactivity and is valuable for further biological studies
  • The present study is the first total synthesis of benzocamphorin F and the developed strategy described is a more efficient procedure that allowe the large-scale production of benzocamphorin F for further research of the biological activity both in vitro and in vivo

Metadata-grounded summary

Citation abstract

A naturally occurring enynyl-benzenoid, benzocamphorin F (1), from the edible fungus Taiwanofungus camphoratus (Antrodia camphorata) was characterized by comprehensive spectral analysis. It displays anti-inflammatory bioactivity and is valuable for further biological studies. The present study is the first total synthesis of benzocamphorin F and the developed strategy described is a more efficient procedure that allowe the large-scale production of benzocamphorin F for further research of the biological activity both in vitro and in vivo.

Citation

Liao YR, Kuo PC, Liang JW, Shen YC, Wu TS (2012). An efficient total synthesis of a potent anti-inflammatory agent, benzocamphorin F, and its anti-inflammatory activity. International journal of molecular sciences https://doi.org/10.3390/ijms130810432 PMID: 22949872

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