Mesima, Sanghwang · 2006 · Research Article
High relevanceAntitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus.
Phellinus linteus
Key points
- Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods
- Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively
- Amino acid pattern showed that two extracts contained large amount of aspartic acid and alanine
- Two extracts showed characteristic IR absorption pattern for glycosidic bond at 890 cm(-1)
- PL-H was divided two fractions by gel filtration chromatography and the molecular weights of each fraction were estimated to be about 10 kD and 225 kD, respectively and also PL-A was estimated 10 kD. Two extracts showed strong antitumor, immunomodulating and antioxidant activities, and were compared with commercialized glycopeptide anticancer drugs
Metadata-grounded summary
Citation abstract
Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively. Amino acid pattern showed that two extracts contained large amount of aspartic acid and alanine. Two extracts showed characteristic IR absorption pattern for glycosidic bond at 890 cm(-1). PL-H was divided two fractions by gel filtration chromatography and the molecular weights of each fraction were estimated to be about 10 kD and 225 kD, respectively and also PL-A was estimated 10 kD. Two extracts showed strong antitumor, immunomodulating and antioxidant activities, and were compared with commercialized glycopeptide anticancer drugs.
Citation
Lee JW, Baek SJ, Bae WC, Park JM, Kim YS (2006). Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus. Mycobiology https://doi.org/10.4489/MYCO.2006.34.4.230 PMID: 24039504
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