Niu-Chang-Chih · 2010 · Patent
High relevanceCYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL FOR TREATING AUTOIMMUNE DISEASES
Antrodia camphorata
Key points
- The present invention relates to a compound of Antrodia camphorata used to treat autoimmune diseases, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, isolated from Antrodia camphorata, and its use in alleviating symptoms of autoimmune diseases such as systemic lupus erythematosus (SLE)
- The cyclohexenone compound according to the present invention helps to decrease proteinuria levels and antinuclear antibody titers in SLE mammals in order to alleviate kidney inflammation and disease, as well as the self-damage caused by antinuclear antibodies
- The purpose for prevention and treatment of autoimmune diseases and kidney diseases by the natural, side-effect free substance can then be accomplished
From the paper
Abstract
The present invention relates to a compound of Antrodia camphorata used to treat autoimmune diseases, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, isolated from Antrodia camphorata, and its use in alleviating symptoms of autoimmune diseases such as systemic lupus erythematosus (SLE). The cyclohexenone compound according to the present invention helps to decrease proteinuria levels and antinuclear antibody titers in SLE mammals in order to alleviate kidney inflammation and disease, as well as the self-damage caused by antinuclear antibodies. The purpose for prevention and treatment of autoimmune diseases and kidney diseases by the natural, side-effect free substance can then be accomplished.
Citation
LIU SHENG-YUN, WEN WU-CHE, KUO MAO-TIEN (2010). CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL FOR TREATING AUTOIMMUNE DISEASES.
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