Niu-Chang-Chih · 2008 · Patent
Medium relevance4-hydroxy-2,3-disubstituted-cyclohex-2-en-1-on-5-yl isoprenoids, extractable from Antrodia camphorata, as anti-tumour & cardiovascular agents, & antioxidant
Antrodia camphorata
Key points
- Compounds of formula (1): '''wherein: X and Y are O or S R' are independently H or C1-13 linear alkyl and n is 1-12 can be isolated and purified from an extract of Antrodia camphorata, and used to inhibit the growth of cancer cells (such as breast cancer, hepatic cancer and prostate cancer), to prevent heart disease and blood vessel disease, and used as an antioxidant dietary supplement
- The preferred compound of formula (1) is 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone
From the paper
Abstract
Compounds of formula (1): '''wherein: X and Y are O or S R' are independently H or C1-13 linear alkyl and n is 1-12 can be isolated and purified from an extract of Antrodia camphorata, and used to inhibit the growth of cancer cells (such as breast cancer, hepatic cancer and prostate cancer), to prevent heart disease and blood vessel disease, and used as an antioxidant dietary supplement. The preferred compound of formula (1) is 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone.
Citation
LIU SHENG-YUN, WEN WU-CHE, TSOU WAN-LING, KUO MAO-TIEN, HUANG CHUN-HUNG, FOK KA-HANG, et al. (2008). 4-hydroxy-2,3-disubstituted-cyclohex-2-en-1-on-5-yl isoprenoids, extractable from Antrodia camphorata, as anti-tumour & cardiovascular agents, & antioxidant.
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