METHOD FOR PREPARING SUBMERGED LIQUID CULTURE OF MUSHROOM MYCELIA HAVING BLOOD GLUCOSE LEVEL LOWERING ACTIVITY

From the paper

Abstract

PURPOSE: A method for preparing submerged liquid culture of mushroom mycelia having blood glucose level lowering activity is provided, which submerged liquid culture of mushroom mycelia inhibits the activity of [alpha]-glucosidase and prevents and treats diabetes.

CONSTITUTION: The method for preparing submerged liquid culture of mushroom mycelia having blood glucose level lowering activity comprises the steps of: treating grains such as soybean meals with protease and cellulase and adding saccharides such as sugar and inorganic salts such as magnesium sulfate or potassium phosphate into the enzyme treated grains to prepare a medium for mushroom mycelia and inoculating mushroom mycelia into the medium and culturing it with stirring or aeration, wherein the mushroom mycelium is selected from Agaricus blazei, Pleurotus ostreatus, Tricholoma matsutake, Flammulina velutipes, Phellinus linteus, Lentinus edodes and Cordyceps militaris.