A new extraction method and application of antrodia camphorata to reduce the damage from chemotherapy for cancer and enhance the erythropoiesis in bone marrow

From the paper

Abstract

We found a new extraction method and application of Antrodia camphorata in promoting and protecting the Erythropoiesis after the chemotherapy of cyclophosphamide. We extracted the Antrodia camphorata with the following procedure: 3 gram powder dissolved in water with 121 DEG C for 10-30 minutes, then centrifuge to discard the precipitates, add the same volume of 95% ethanol, then shaking for 8 hours, centrifuge again with 4000 rpm for 10 minutes, discard the precipitates, keep the supernatant do the following experiments. In the in vivo experiment, we found the peripheral blood cell number increase from 2.7000 +- 1.0801x10 /ul to 4.6250 +- 4.2161x10 /ul after the cyclophosphamide injection in the water and Antrodia camphorata treatment, respectively. In the in vitro experiment, we scarified the mice with cyclophosphamide injection after 6 days feeding with Antrodia camphorata, took out of mice bone marrow cells and cultivated to count the colony numbers, the number increase from 23.7500 +- 5.9090 to 42.0000 +- 4.9666 in the positive and negative control, respectively.