Maitake, Hen of the Woods · 2010 · Patent
Low relevanceBeta-Glucan Enhances Hematopoietic Progenitor Cells Engraftment and Promotes Recovery from Chemotoxicity
Grifola frondosa
Key points
- Methods to use beta glucans in the culture of cell populations containing CD34+ cells in order to expand the numbers of CD34+ subsets of progenitor and stem cells are provided
- Methods to improve homing and engraftment of stem and progenitor cells by first culturing the cells with beta glucans, or co-administering with beta glucans, are also provided
- Additionally, methods to ameliorate chemotherapy toxicity and promote development of functionally active neutrophils by administering beta glucans are presented
- The beta glucans are preferably extracted from maitake mushroom (Grifola frondosa)
From the paper
Abstract
Methods to use beta glucans in the culture of cell populations containing CD34+ cells in order to expand the numbers of CD34+ subsets of progenitor and stem cells are provided. Methods to improve homing and engraftment of stem and progenitor cells by first culturing the cells with beta glucans, or co-administering with beta glucans, are also provided. Additionally, methods to ameliorate chemotherapy toxicity and promote development of functionally active neutrophils by administering beta glucans are presented. The beta glucans are preferably extracted from maitake mushroom (Grifola frondosa).
Citation
CUNNINGHAM-RUNDLES SUSANNA, SMITH-JONES HONG LIN (2010). Beta-Glucan Enhances Hematopoietic Progenitor Cells Engraftment and Promotes Recovery from Chemotoxicity.
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