Proteoglucan and antidiabetic drug thereof

From the paper

Abstract

This Invention is to provide a proteoglucan and an antidiabetes drug containing the proteoglucan, as an active ingredient, which possess an excellent effect against non-insulin dependent diabetes mellitus. The proteoglucan under this Invention has beta -1,6 main chain with alpha -1,4 branched, with the average molecular weight of 2x105, acting positive both in anthrone-sulfuric acid method and Lowry's method, having the chemical structure as indicated in the following general formula. +TR The above proteoglucan is obtained easily through the hot-water extraction from fruit body and/or mycellium of Maitake and/or Chorei Maitake. This proteoglucan has an activity to ameliorate the glucose transport and bioavailability at myocardium, skeltal muscles and fat tissue cells, etc. of the patient with non-insulin dependent diabetes mellitus, and is very useful as a pharmaceutical composition to treat and/or prevent from non-insulin dependent diabetes mellitus.