Snow Fungus, Silver Ear · 1992 · English Abstract
Low relevance[Effect of Tremella polysaccharide on IL-2 production by mouse splenocytes].
Tremella fuciformis
Key points
- Tremella polysaccharide (TP) is an important component isolated from Tremella fuciformis Berk
- In this study, the in vitro effect of TP on IL-2 production was examined in activated mouse splenocytes
- TP (1, 5, 10 and 50 micrograms/ml) significantly increased mouse splenocyte IIL-2 production
- In aged mice, the level of IL-2 production is much lower than that in young controls
- Furthermore, TP (0.05, 0.5 and 5 micrograms/ml) was found to partly antagonize the suppressive effect of hydrocortisone on IL-2 production
- The antagonistic effect of TP (5 micrograms/ml) on the inhibitory activity of cyclosporin A was also observed
Metadata-grounded summary
Citation abstract
Tremella polysaccharide (TP) is an important component isolated from Tremella fuciformis Berk. In this study, the in vitro effect of TP on IL-2 production was examined in activated mouse splenocytes. TP (1, 5, 10 and 50 micrograms/ml) significantly increased mouse splenocyte IIL-2 production. In aged mice, the level of IL-2 production is much lower than that in young controls. TP (0.05, 0.5 and 5 micrograms/ml) restored the IL-2 production to normal level as the young control. Furthermore, TP (0.05, 0.5 and 5 micrograms/ml) was found to partly antagonize the suppressive effect of hydrocortisone on IL-2 production. The antagonistic effect of TP (5 micrograms/ml) on the inhibitory activity of cyclosporin A was also observed.
Citation
Ma L, Lin ZB (1992). [Effect of Tremella polysaccharide on IL-2 production by mouse splenocytes]. Yao xue xue bao = Acta pharmaceutica Sinica PMID: 1529707
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