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Chaga · 2015 · English Abstract

Medium relevance

[Antiviral activity of aqueous extracts of the birch fungus Inonotus obliquus on the human immunodeficiency virus].

Inonotus obliquus

Metabolic healthSkin & hydrationRespiratory
SpeciesChaga
JournalVoprosy virusologii
Year2015

Key points

  • Fractions of aqueous and water-alcohol extracts of the birch fungus Inonotus obliquus have antiviral effect against the human immunodeficiency virus type 1 (HIV-1)
  • Antiviral properties of low toxic extracts were manifested in the concentration of 5.0 μg/ml upon simultaneous application with the virus in the lymphoblastoid cells culture MT-4
  • The extract of the birch fungus can be used for development of new antiviral drugs, inhibitors of HIV-replication when used both in the form of individual drugs and as a part of complex therapy

Metadata-grounded summary

Citation abstract

Fractions of aqueous and water-alcohol extracts of the birch fungus Inonotus obliquus have antiviral effect against the human immunodeficiency virus type 1 (HIV-1). Antiviral properties of low toxic extracts were manifested in the concentration of 5.0 μg/ml upon simultaneous application with the virus in the lymphoblastoid cells culture MT-4. The extract of the birch fungus can be used for development of new antiviral drugs, inhibitors of HIV-replication when used both in the form of individual drugs and as a part of complex therapy.

Citation

Shibnev VA, Garaev TM, Finogenova MP, Kalnina LB, Nosik DN (2015). [Antiviral activity of aqueous extracts of the birch fungus Inonotus obliquus on the human immunodeficiency virus]. Voprosy virusologii PMID: 26182655

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