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Almond Mushroom, ABM · 2023 · Review

Medium relevance

Increased intracranial pressure in acute bacterial meningitis.

Agaricus blazei

Immune support
SpeciesAlmond Mushroom, ABM
JournalUgeskrift for laeger
Year2023

Key points

  • Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection
  • Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality
  • The ICP increase may have a rapid course and death due to herniation is most often seen within the first week
  • Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM

Metadata-grounded summary

Citation abstract

Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week. Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM.

Citation

Hvas CL, Andersen ÅB, Møller K, Hansen K, Poulsen FR, Overgaard-Steensen C (2023). Increased intracranial pressure in acute bacterial meningitis. Ugeskrift for laeger PMID: 38105735

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