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Articles under this record
2024 · Review · Frontiers in pharmacology
Current and further outlook on the protective potential of Antrodia camphorata against neurological disorders.
Prevalent neurological disorders such as Alzheimer's disease, Parkinson's disease, and stroke are increasingly becoming a global burden as society ages. It is well-known that degeneration and loss of neurons are the fundamental underlying processes, but there are still no effective therapies for these neurological….
Open article2025 · Review · ACS omega
Biological Functions and Synthesis of the Active Components in Antrodia camphorata.
As a fungus endemic to Taiwan, Antrodia camphorata contains a variety of medicinally active substances, such as polysaccharides, triterpenoids, maleic acid and succinic acid derivatives, and ubiquinone derivatives. A..
Open article2023 · Journal Article · Environmental toxicology
Antrodia camphorata and coenzyme Q0, a novel quinone derivative of Antrodia camphorata, impede HIF-1α and epithelial-mesenchymal transition/metastasis in human glioblastoma cells.
Antrodia camphorata (AC) and Coenzyme Q0 (CoQ0 ), a novel quinone derivative of AC, exhibits antitumor activities. The present study evaluated EMT/metastasis inhibition and autophagy induction aspects of AC and CoQ0 in human glioblastoma (GBM8401) cells..
Open article2022 · Research Article · Frontiers in pharmacology
Clinical Benefits of Golden-Antrodia Camphorata Containing Antroquinonol in Liver Protection and Liver Fat Reduction After Alcoholic Hepatitis.
Objective: It has been reported that antroquinonol extracted from Golden-Antrodia camphorate exerts protective effects on liver function both in vitro and in vivo. However, the protective effects of Golden-Antrodia camphorata on liver function have not been fully investigated in human clinical studies..
Open article2022 · Research Article · EFSA journal. European Food Safety Authority
Safety of freeze-dried mycelia of Antrodia camphorata as a novel food pursuant to regulation (EU) 2015/2283.
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on freeze-dried mycelia of Antrodia camphorata as a novel food (NF) pursuant to Regulation (EU) 2015/2283..
Open article2021 · Journal Article · Journal of ethnopharmacology
Antrodia camphorata extract (ACE)-induced apoptosis is associated with BMP4 expression and p53-dependent ROS generation in human colon cancer cells.
ETHNOPHARMACOLOGICAL RELEVANCE: Antrodia camphorata (AC) is a rare functional fungus in Taiwan and is known as traditional Chinese medicine. It has been reported to inhibit proliferation and promote apoptosis in human cancer cells..
Open article2026 · Journal Article · Angewandte Chemie (International ed. in English)
A Unique CYP450 Enzyme Unlocks Antrodia Camphorata Lanostane Triterpenoid Diversity Through Oxidation and Skeletal Rearrangement.
Lanostane triterpenoids, key therapeutic components of medicinal mushrooms, such as rare Antrodia camphorata, face heterologous biosynthesis barriers due to the lack of enzymes for essential C21/C15 oxidation and skeletal rearrangement, limiting access to these rare therapeutics..
Open article2025 · Journal Article · Journal of functional foods
Coenzyme Q0, a quinone derivative from Antrodia camphorata, triggered ROS-mediated cytoprotective autophagy in human promyelocytic leukemia cells
Our previous investigation revealed that Coenzyme Q₀ (CoQ₀), a quinone derivative from Antrodia camphorata, triggered ROS-dependent voltage-dependent anion channel 1 (VDAC-1)-mediated apoptosis in human promyelocytic leukemia (HL-60) cells..
Open article