MycoData

Reishi · 2024 · Research Article · Current research in food science

Understanding the characteristic changes of retrogradation behavior and edible quality of brown rice modified with inhibiting retrogradation enzymes of Ganoderma lucidum.

Brown rice (BR) has gradually become a new choice for consumers due to its exceptionally nutritional value. Whereas starch retrogradation profoundly reduces its edibility, shelf-life and consumer acceptance, limiting the development of BR and even other starch-based food products..

Almond Mushroom · 2023 · Clinical Trial Protocol · Contemporary clinical trials

Combining antidepressants and attention bias modification in primary health care (DEPTREAT): Protocol for a pragmatic randomized controlled trial.

BACKGROUND: Major depressive disorder (MDD) is a highly prevalent psychiatric condition associated with significant disability, mortality and economic burden. A large proportion of MDD patients are treated in primary health care in the local community..

Immune supportCognition & nervesEnergy & fatigue

Nameko · 2022 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Chemical properties and anti-fatigue effect of polysaccharide from Pholiota nameko.

The aim of this study was to explore the primary chemical properties and anti-fatigue effect in vivo of Pholiota nameko polysaccharide (PNP). Through UV-visible spectrum, the absorption peaks of proteins, nucleic acids and pigments were not found..

Cognition & nervesLiver support

Almond Mushroom · 2021 · Clinical Trial Protocol · Trials

Protocol for the methamphetamine approach-avoidance training (MAAT) trial, a randomised controlled trial of personalised approach bias modification for methamphetamine use disorder.

BACKGROUND: Globally, methamphetamine use has increased in prevalence in recent years. In Australia, there has been a dramatic increase in numbers of people seeking treatment, including residential rehabilitation, for methamphetamine use disorder (MUD)..

Lion's Mane · 2026 · Systematic Review · Medical sciences (Basel, Switzerland)

Application of Medicinal Mushrooms for the Treatment of Peripheral Nerve Injury: A Systematic Review.

Background/Objective: Current treatments for peripheral nerve injury (PNI) lack robust evidence to suggest complete recovery; hence, alternative therapeutics offer new opportunities to develop more effective protocols..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2026 · Review · Die Naturwissenschaften

Research advances on Cordyceps sinensis and its components in relation to omics biomarkers for the neurological disorders.

Cordyceps is a traditional medicinal fungus belonging to the species Ophiocordyceps sinensis. It grows in the alpine ecological zone of the Tibetan Plateau and exhibits dual characteristics of both insects and fungi.

OncologyImmune supportCognition & nervesMetabolic health

Reishi · 2025 · Systematic Review · Carbohydrate research

Structural basis of immunomodulation by edible fungal polysaccharides: From molecular characteristics to action mechanisms.

Edible Fungal polysaccharides as Immunomodulators: A Systematic Review at the Crossroads of Immunology, Natural Products Chemistry, and Microbiology. The chemical structure-specifically molecular weight, branching degree, and functional group modifications-directly dictates immunological activity..

Almond Mushroom · 2024 · Review · Biomimetics (Basel, Switzerland)

Review of the Brain's Behaviour after Injury and Disease for Its Application in an Agent-Based Model (ABM).

The brain is the most complex organ in the human body and, as such, its study entails great challenges (methodological, theoretical, etc.). Nonetheless, there is a remarkable amount of studies about the consequences of pathological conditions on its development and functioning..

Cognition & nervesMetabolic healthGut & microbiome

King Oyster · 2023 · Research Article · Microorganisms

In Vitro Fermentation of Edible Mushrooms: Effects on Faecal Microbiota Characteristics of Autistic and Neurotypical Children.

Children with autism spectrum disorder (ASD) often suffer gastrointestinal disturbances consistent with gut microbiota (GM) alterations. Treatment with pro/prebiotics may potentially alleviate gut symptoms, but the evidence for prebiotics is scarce..

Immune supportCognition & nervesMetabolic health

King Oyster · 2022 · Journal Article · International journal of medicinal mushrooms

Suppressive Effect of Fruiting Bodies of Medicinal Mushrooms on Demyelination and Motor Dysfunction in a Cuprizone-Induced Multiple Sclerosis Mouse Model.

Epidemiologic studies have shown a high prevalence of multiple sclerosis (MS) in Europe and North America, and a low prevalence in East Asia. Mushrooms contain various biological response modifiers (BRMs) and are widely used in traditional Chinese medicine in East Asian countries..

Cognition & nervesMetabolic health

Almond Mushroom · 2020 · Preprint · journal metadata

Effects of Transcranial Direct Current Stimulation (tDCS) and Approach Bias Modification training (ABM) on food cravings in people taking antipsychotic medication

Abstract Background Antipsychotic drug induced weight gain puts individuals with schizophrenia at increased cardiometabolic risk. As a potential intervention for this problem we describe the theoretical background and a protocol for a feasibility randomised controlled trial (RCT) of approach bias modification training….

Cognition & nervesSkin & hydration

Lion's Mane · 2020 · Research Article · Frontiers in aging neuroscience

Prevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study.

OBJECTIVE: To investigate the efficacy and safety of three H. erinaceus mycelia (EAHE) capsules (350 mg/capsule; containing 5 mg/g erinacine A active ingredient) per day for the treatment of patients with mild Alzheimer's Disease (AD)..

Cordyceps · 2019 · Abstract · Current developments in nutrition

A Systematic Review of in-vivo Studies on Dietary Mushroom Supplementation for Cognitive Impairment (P14-021-19)

Abstract Objectives A systematic review was undertaken of the evidence on the use of Hericium erinaceus (Reishi), Ganoderma lucidum (Lion's Mane), Ophiocordyceps sinensis (Cordyceps) and Cordyceps militaris (Cordyceps), dietary supplementation on cognitive impairment outcomes..

Lion's Mane · 2018 · Journal Article · Journal of Health Psychology Research

Application of the active ingredients extracted from Hericium Erinaceus to mental health

Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Journal of Health Psychology Research in 2018. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..

OncologyImmune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2016 · Research Article · Immunity & ageing: I & A

Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer's disease pathogenesis.

BACKGROUND: There has been a recent upsurge of interest in complementary medicine, especially dietary supplements and foods functional in delaying the onset of age-associated neurodegenerative diseases..

Almond Mushroom · 2022 · Systematic Review · International journal of environmental research and public health

Agent-Based Modelling of Health Inequalities following the Complexity Turn in Public Health: A Systematic Review.

There is an increasing focus on the role of complexity in public health and public policy fields which has brought about a methodological shift towards computational approaches..

Almond Mushroom · 2021 · Systematic Review · Psychophysiology

A systematic review of event-related potentials as outcome measures of attention bias modification.

Attention bias modification (ABM) was initially developed with the goal of reducing attentional bias to threat-and subsequently anxious symptoms-in individuals with heightened anxiety. Although controversial, ABM appears to be generally effective in achieving this goal..

Almond Mushroom · 2021 · Meta-Analysis · Psychiatry research

Attention bias modification for anxiety disorders in children and adolescents: A systematic review and meta-analysis.

Despite accumulating evidence suggesting the effectiveness of Attention Bias Modification (ABM) in adults, little is known about its efficacy in children and adolescents..

Almond Mushroom · 2021 · Meta-Analysis · Psychiatry research

Can attention bias modification augment the effect of CBT for anxiety disorders? A systematic review and meta-analysis.

Attention Bias Modification (ABM) is a novel computerized therapy for anxiety disorders and is thought to augment the effect of Cognitive Behavior Therapy (CBT) as it may target different mechanisms..

OncologyImmune supportCognition & nervesLiver support

Niu-Chang-Chih · 2005 · Research Support, Non U.S. Gov'T · FEMS microbiology letters

Antrodia camphorata prevents rat pheochromocytoma cells from serum deprivation-induced apoptosis.

Antrodia camphorata (A. camphorata) is a rare medicinal fungus with antioxidative, vasorelaxtative, anti-inflammatory and anti-hepatitive effects.

Mesima · 2004 · Research Support, Non U.S. Gov'T · Planta medica

A beta-secretase (BACE1) inhibitor hispidin from the mycelial cultures of Phellinus linteus.

In the course of screening for anti-dementia agents from natural products, a beta-secretase (BACE1) inhibitor was isolated from the culture broth of Phellinus linteus and identified as hispidin. It showed an IC (50) value of 4.9 x 10 (-6) M and a Ki value of 8.4 x 10 (-6) M..

OncologyImmune supportCognition & nerves

Mesima · 2004 · Research Support, Non U.S. Gov'T · International journal of molecular medicine

Induction of apoptotic cell death by mycelium extracts of Phellinus linteus in human neuroblastoma cells.

Phellinus linteus is a well-known Oriental medicinal fungus that has various biological activities, including immunomodulatory and anti-tumor activities, the mechanisms of which are poorly understood. In the present study, we investigated the effects of mycelium extracts of P..

Cognition & nervesLiver support

Niu-Chang-Chih · 2003 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Antioxidative and hepatoprotective effects of Antrodia camphorata extract.

Antrodia camphorata (A. camphorata) is well-known in Taiwan as a traditional Chinese medicine.

Enoki · 2002 · Research Support, Non U.S. Gov'T · Protein science: a publication of the Protein Society

Active site geometry of oxalate decarboxylase from Flammulina velutipes: Role of histidine-coordinated manganese in substrate recognition.

Oxalate decarboxylase (OXDC) from the wood-rotting fungus Flammulina velutipes, which catalyzes the conversion of oxalate to formic acid and CO(2) in a single-step reaction, is a duplicated double-domain germin family enzyme. It has agricultural as well as therapeutic importance..

Cognition & nervesEnergy & fatigue

Enoki · 2000 · Research Support, Non U.S. Gov'T · FEMS microbiology letters

Basidiomycetous fungus Flammulina velutipes harbors two linear mitochondrial plasmids encoding DNA and RNA polymerases.

Basidiomycetous fungus Flammulina velutipes R15 strain had two linear plasmids in its mitochondria designated pFV1 and pFV2. They were double-stranded DNAs, whose sizes were 8.3 and 8.9 kb, respectively..

Enoki · 1995 · Research Support, Non U.S. Gov'T · European journal of cell biology

Actin filaments are involved in cellular graviperception of the basidiomycete Flammulina velutipes.

Inhibitor studies demonstrate a major role of the actin cytoskeleton in cellular graviperception of the basidiomycete Flammulina velutipes. Treatment of explanted fruiting body stipes with 10(-4) M of the actin filament-disrupting agent cytochalasin D causes specific suppression of gravitropic curvature to 21% of the….

Cognition & nervesRespiratory

Almond Mushroom · 2025 · Review · Journal of intensive care medicine

Lumbar Puncture and Brain Herniation in Acute Bacterial Meningitis: An Updated Narrative Review.

The risk of lumbar puncture (LP) to precipitate brain herniation in acute bacterial meningitis (ABM) was reviewed in this journal in 2007. We report the case of an infant with ABM who had acute apnea requiring intubation and tonic posturing (mistaken for seizure), and then had brain herniation within four hours of an….

Oyster Mushroom · 2024 · Data Paper · Data in brief

A novel dataset of annotated oyster mushroom images with environmental context for machine learning applications.

State-of-the-art technologies such as computer vision and machine learning, are revolutionizing the smart mushroom industry by addressing diverse challenges in yield prediction, growth analysis, mushroom classification, disease and deformation detection, and digital twinning..

Almond Mushroom · 2024 · Review · Genes

Assessing the Impact and Cost-Effectiveness of Exposome Interventions on Alzheimer's Disease: A Review of Agent-Based Modeling and Other Data Science Methods for Causal Inference.

Background: The exposome (e.g., totality of environmental exposures) and its role in Alzheimer's Disease and Alzheimer's Disease and Related Dementias (AD/ADRD) are increasingly critical areas of study..

Cognition & nervesEnergy & fatigue

Lion's Mane · 2024 · Scoping Review · Journal of the American Nutrition Association

The Role of Dietary Ingredients in Mental Energy - A Scoping Review of Randomized Controlled Trials.

Low mental energy can contribute to decreased productivity, altered life balance, decreased physical performance, and ultimately affect quality of life. As such, there is a great demand for food and beverage products that positively impact mental energy..

Cognition & nervesRespiratory

Almond Mushroom · 2023 · Research Article · Procedia computer science

An Intelligent ABM-based Framework for Developing Pandemic-Resilient Urban Spaces in Post-COVID Smart Cities.

As of August 2022, the COVID-19 pandemic has accounted for over six million deaths globally. The urban population has been severely affected by this viral pandemic and the ensuing lockdowns, resulting in increased poverty and inequality, slowed economic growth, and a general decline in quality of life..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2023 · Research Article · Nutrients

Cordyceps cicadae NTTU 868 Mycelia Fermented with Deep Ocean Water Minerals Prevents D-Galactose-Induced Memory Deficits by Inhibiting Oxidative Inflammatory Factors and Aging-Related Risk Factors.

Cordyceps cicadae, a medicinal fungus that is abundant in bioactive compounds such as N6-(2-hydroxyethyl)-adenosine (HEA) and polysaccharides, possesses remarkable anti-inflammatory, antioxidant, and nerve damage recovery properties..

Immune supportCognition & nervesEnergy & fatigue

Shiitake · 2023 · Journal Article · Journal of food composition and analysis

Determination of polysaccharide content in shiitake mushroom beverage by NIR spectroscopy combined with machine learning: A comparative analysis

A comprehensive comparative analysis of the performance of near-infrared (NIR) spectroscopy combined with various chemometrics and machine learning methods was performed to quantitatively determine polysaccharide content in shiitake mushroom beverages..

Immune supportCognition & nervesEnergy & fatigueSkin & hydration

Cordyceps · 2023 · Research Article · Nutrients

Preventative Effects of Cordyceps cicadae Mycelial Extracts on the Early-Stage Development of Cataracts in UVB-Induced Mice Cataract Model.

Cataracts, a prevalent age-related eye condition, pose a significant global health concern, with rising rates due to an aging population and increased digital device usage. In Taiwan, cataract prevalence is particularly high, reaching up to 90% among individuals aged 70 and above..

Cognition & nervesMetabolic health

Wood Ear · 2023 · Research Article · BioMed research international

The Polyherbal Functional Ingredient Containing Ginger, Chinese Date, and Wood Ear Mushroom Protects against Dementia following Metabolic Syndrome.

The anti-dementia effect following ischemic stroke with metabolic syndrome (MetS) of the polyherbal functional ingredient comprising ginger, Chinese date, and wood ear mushroom (GCJ) was hypothesized due to its neuroprotective effect against stroke..

Cognition & nervesEnergy & fatigue

Cordyceps · 2022 · Journal Article · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Identification of Cordyceps cicadae and Tolypocladium dujiaolongae based on ITS sequences and chemical pattern recognition method].

Based on ITS sequences, the molecular identification of Cordyceps cicadae and Tolypocladium dujiaolongae was carried out, and high-performance liquid chromatography(HPLC) fingerprint combined with chemical pattern recognition method was established to differentiate C. cicadae from its adulterant T.

Cognition & nervesLiver support

Cordyceps · 2022 · Journal Article · International journal of clinical pharmacology and therapeutics

Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis.

The use of herbal and dietary supplements is increasing worldwide. Consumers consider it as a natural, and therefore safe and healthy alternative to conventional synthetic drugs and do not expect adverse effects..

Immune supportCognition & nervesMetabolic health

Wood Ear · 2022 · Research Article · BioMed research international

Neuroprotective Effect of Polyherbal Recipe Containing Ginger, Chinese Date, and Wood Ear Mushroom against Ischemic Stroke with Metabolic Syndrome Condition via Epigenetic Modification of Inflammation and Oxidative Stress.

Currently, the prevalence of stroke with metabolic syndrome (MetS) is increasing and the current therapeutic efficiency is still limited. Therefore, the applications of herbal recipes have gained much attention..

Cordyceps · 2022 · Journal Article · International journal of medicinal mushrooms

Neuroprotective Effects of Cordyceps cicadae (Ascomycetes) Mycelium Extract in the Rat Model of Optic Nerve Crush.

Cordyceps cicadae mycelium is an herbal medicine used to provide anti-inflammatory and antiapoptotic actions. However, little is known about the role of C.

Almond Mushroom · 2020 · Randomized Controlled Trial · Journal of behavior therapy and experimental psychiatry

A pilot study augmenting cognitive behavioral therapy for panic disorder with attention bias modification: Clinical and psychophysiological outcomes.

BACKGROUND AND OBJECTIVES: Studies show that attentional bias towards threat is a key maintenance factor for panic disorder (PD). Attentional bias may be an important mechanism of symptom reduction, and thus, a useful target for optimizing outcomes..

Almond Mushroom · 2020 · Randomized Controlled Trial · Brain and behavior

Time course of pupillary response to threat words before and after attention bias modification for transdiagnostic anxiety disorders: A randomized controlled trial.

INTRODUCTION: Altered attention to threatening stimuli at initial and sustained stages of processing may be dissociable dimensions that influence the development and maintenance of transdiagnostic symptoms of anxiety, such as vigilance, and possibly require distinct intervention..

Almond Mushroom · 2019 · Randomized Controlled Trial · Child psychiatry and human development

Efficacy of Attention Bias Training for Child Anxiety Disorders: A Randomized Controlled Trial.

A growing evidence base supports attention bias modification (ABM) as a novel intervention for anxiety. However, research has been largely conducted with adults and analogue samples, leaving the impact of ABM for child anxiety be fully elucidated..

OncologyImmune supportCognition & nervesMetabolic health

Enoki · 2016 · Review · Frontiers in pharmacology

Golden Needle Mushroom: A Culinary Medicine with Evidenced-Based Biological Activities and Health Promoting Properties.

Flammulina velutipes (enoki, velvet shank, golden needle mushroom or winter mushroom), one of the main edible mushrooms on the market, has long been recognized for its nutritional value and delicious taste..

Immune supportCognition & nervesEnergy & fatigueLiver support

Cordyceps · 2025 · Research Article · Scientific reports

Cordycepin combined with antioxidant effects improves fatigue caused by excessive exercise.

Excessive exercise can lead to physical fatigue and disruption of the antioxidant system, resulting in neurological damage and cognitive decline. Cordycepin, the main component of Cordyceps militaris, has anti-inflammatory, antioxidant and neuroprotective effects..

Immune supportCognition & nervesEnergy & fatigueGut & microbiome

Cordyceps · 2025 · Journal Article · Molecular neurobiology

Cordycepin Mitigates Sepsis-Associated Encephalopathy by Promoting Microglial M2 Polarization via the IL-17a/IL-17RA/NF-κB Axis.

Sepsis-associated encephalopathy (SAE) is a serious neurological complication of systemic infection, marked by cognitive deficits, neuroinflammation, and increased mortality. Microglial activation and proinflammatory signaling pathways, particularly involving IL-17a and NF-κB, are key contributors to SAE pathogenesis..

Cordyceps · 2025 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Evaluation of antidepressant and sleep-promoting effects of cordycepin in a menopause-like stress model.

The menopausal transition is often accompanied by mood disturbances and sleep disorders, exacerbated by estrogen deficiency and chronic stress. Although hormone replacement therapy (HRT) is effective, its use is limited by safety concerns, underscoring the need for non-hormonal alternatives..

Cordyceps · 2025 · Journal Article · Current biology: CB

Neuroparasitology: Fungal effectors induce feeding in zombie silkworms.

Some entomopathogenic fungi hijack host behavior to increase their pathogenicity, but how they do so has largely remained a mystery. A recent paper shows that Cordyceps militaris fungi produce insect-like trehalase enzymes to induce perceived starvation in silkworms, leading to increased feeding and greater production….

Cordyceps · 2024 · Research Article · Neural regeneration research

3'-Deoxyadenosin alleviates methamphetamine-induced aberrant synaptic plasticity and seeking behavior by inhibiting the NLRP3 inflammasome.

JOURNAL/nrgr/04.03/01300535-202410000-00028/figure1/v/2024-02-06T055622Z/r/image-tiff Methamphetamine addiction is a brain disorder characterized by persistent drug-seeking behavior, which has been linked with aberrant synaptic plasticity..