MycoData

Recent studies highlight the immunomodulatory properties of Chaga mushrooms. Atopic dermatitis (AD) is a multifactorial skin disorder involving interactions between innate and adaptive immune responses..

Immune supportSkin & hydration

High relevance

Cordyceps · 2026 · Research Article · Life (Basel, Switzerland)

Cordyceps militaris Enhances Wound Repair Through Regulation of HIF-1α, TGF-β1, and SIRT1/Nrf2/HO-1 Signaling in Diabetic Skin.

Chronic diabetic wounds are characterized by persistent inflammation, impaired angiogenesis, oxidative stress, and defective tissue remodeling, leading to delayed healing..

Immune supportMetabolic healthSkin & hydration

High relevance

Shiitake · 2026 · Research Article · Journal of cosmetic dermatology

Cosmeceutical and Dermatological Potential of Shiitake Mushroom (Lentinula edodes) Extract.

BACKGROUND: Shiitake mushroom (Lentinula edodes) contains polysaccharides, phenolics, and β-glucans known for their antioxidant and nutraceutical properties; however, its dermatological applications remain limited..

OncologyImmune supportSkin & hydration

High relevance

Reishi · 2026 · Journal Article · International journal of cosmetic science

Cosmetic potential of Ganoderma lucidum (Reishi) extract in a topical cream formulation.

OBJECTIVE: The primary objective of this study was to investigate the biological activities of freeze-dried Ganoderma lucidum (Reishi) extract obtained from hazelnut pruning waste and to compare its antioxidant, tyrosinase inhibitory and cytotoxic properties with two widely used cosmetic actives-argireline peptide and….

OncologyEnergy & fatigueSkin & hydration

High relevance

King Oyster · 2026 · Journal Article · Journal of food engineering

Dual role of reusable Zingiber officinale in microwave synergistic drying of Pleurotus eryngii: Dielectric regulation and composite flavor formation

Microwave drying dehydrates rapidly but is limited by uneven heating and quality loss. To tackle this challenge, a mixed material system was designed by combining Pleurotus eryngii with reusable Zingiber officinale, where Z..

Skin & hydration

High relevance

Chaga · 2026 · Journal Article · Photochemical & photobiological sciences: Official journal of the European Photochemistry Association and the European Society for Photobiology

Inonotus obliquus polysaccharides alleviate UVB-irradiated skin photodamage by regulating calcium homeostasis through endoplasmic reticulum-mitochondria crosstalk.

Skin photodamage is closely related to mitochondrial dysfunction, and endoplasmic reticulum (ER) stress can induce excessive mitochondrial reactive oxygen species (ROS) accumulation, triggering inflammation, and inducing cell apoptosis..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Lion's Mane · 2026 · Preprint · journal metadata

Methyl viologen boosts Erinacine A biosynthesis in Hericium erinaceus fermentation: Multi-omics insights

Abstract Erinacine A, a critical secondary metabolite of Hericium erinaceus, has garnered significant interest due to its bioactive properties. This study aimed to investigate the effects of methyl viologen (MV) on the synthesis of Erinacine A during liquid fermentation of Hericium erinaceus, employing a multi-omics….

Cognition & nervesEnergy & fatigueMetabolic healthSkin & hydration

High relevance

Oyster Mushroom · 2026 · Journal Article · Burns: journal of the International Society for Burn Injuries

Oral Pleurotus ostreatus supplementation modulates systemic inflammation and enhances collagen density in a full-thickness burn rat model.

Severe burn injuries cause hypermetabolic and inflammatory responses characterized by hypoalbuminemia and elevated cytokines that delay wound healing. Pleurotus ostreatus, known for its bioactive compounds and high-quality protein, may support recovery by improving systemic nutritional and inflammatory balance..

OncologyImmune supportMetabolic healthSkin & hydration

High relevance

Reishi · 2026 · Journal Article · Experimental eye research

Protective effects of topical and oral Ganoderma lucidum extracts against ultraviolet B-induced cataract development and chemical ocular surface injury in a rat model.

PURPOSE: To evaluate protective and therapeutic effects of oral and topical Ganoderma lucidum in a rat model of ultraviolet B (UVB)- and sodium hydroxide (NaOH)-induced ocular injury. METHODS: Twenty-eight male Sprague-Dawley rats were allocated to sham, injury, oral G.

Skin & hydration

High relevance

Chaga · 2026 · Journal Article · Planta medica

Quantitative Analysis and Simultaneous Characterization of Triterpenoids and Phenolics in Inonotus obliquus (Chaga) Using LC-PDA-ELSD and LC-DAD-QToF.

Inonotus obliquus is widely recognized as the Chaga mushroom. Chaga contains various bioactive compounds, including polysaccharides, triterpenoids, polyphenols, and melanin..

Immune supportSkin & hydration

High relevance

King Oyster · 2026 · Journal Article · Food research international (Ottawa, Ont.)

Synergistic regulation of P. eryngii quality and protein properties by dielectric-guided gradient conversion drying and ultrasound-assisted functional rehydration of by-products.

Quality deterioration and underutilization of by-products (Pleurotus eryngii root wastes) limit the industrial drying and protein valorization of Pleurotus eryngii (P. eryngii)..

Skin & hydration

High relevance

Cordyceps · 2025 · Journal Article · Microbial Pathogenesis

Bovine serum albumin-chitosan nanoparticles loaded with Cordyceps militaris extract: A novel approach to combat MDR bacteria

The application of Bovine Serum Albumin (BSA) nanoparticles in the medical field has gained substantial attention due to their biocompatibility and multifunctionality as drug delivery systems..

OncologyLiver supportSkin & hydration

High relevance

Cordyceps · 2025 · Journal Article · Microbial pathogenesis

Bovine serum albumin-chitosan nanoparticles loaded with Cordyceps militaris extract: A novel approach to combat MDR bacteria.

The application of Bovine Serum Albumin (BSA) nanoparticles in the medical field has gained substantial attention due to their biocompatibility and multifunctionality as drug delivery systems..

OncologyLiver supportSkin & hydration

High relevance

King Oyster · 2025 · Journal Article · Carbohydrate polymers

Carboxymethyl chitosan-induced modification of the structure and regulation of the thermal aggregation of Pleurotus eryngii protein fractions to improve gel properties

In recent years, interactions between polysaccharides and proteins have been widely considered for use to improve protein gel performances. We previously found carboxymethyl chitosan (CMCS) can increase Pleurotus eryngii protein (PEP) gel properties, but the contributions of different key PEP fractions to overall gel….

Immune supportEnergy & fatigueSkin & hydration

High relevance

King Oyster · 2025 · Journal Article · Carbohydrate polymers

Carboxymethyl chitosan-induced modification of the structure and regulation of the thermal aggregation of Pleurotus eryngii protein fractions to improve gel properties.

Immune supportEnergy & fatigueSkin & hydration

High relevance

Cordyceps · 2025 · Research Article · International journal of molecular sciences

Chitosan Nanoparticle-Encapsulated Cordyceps militaris Grown on Germinated Rhynchosia nulubilis Reduces Type II Alveolar Epithelial Cell Apoptosis in PM2.5-Induced Lung Injury.

Chitosan nanoparticles (CNPs) were synthesized in this study to enhance the limited bioactivity and stability of Cordyceps militaris grown on germinated Rhynchosia nulubilis (GRC) and effectively deliver it to target tissues..

OncologyEnergy & fatigueLiver supportSkin & hydration

High relevance

Reishi · 2025 · Journal Article · South African journal of botany

Cold atmospheric plasma is a potent tool to improve cosmetic bioactive compounds in Ganoderma lucidum suspension cultures

In the current decade, biological researchers have explored the use of cold plasma elicitors to increase the production of secondary metabolites in laboratory settings because of limitations in the natural harvesting of medicinal plants and fungi..

Immune supportSkin & hydration

High relevance

King Oyster · 2025 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Comparative analysis of electrohydrodynamic, hot air, and natural air drying techniques on quality attributes and umami enhancement in king oyster mushroom (Pleurotus eryngii)

This study systematically examined the impacts of three distinct drying techniques (Electrohydrodynamics, Hot air and Natural air) on the physicochemical characteristics of king oyster mushroom..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Cordyceps · 2025 · Review · Gels (Basel, Switzerland)

Cordyceps militaris-Derived Bioactive Gels: Therapeutic and Anti-Aging Applications in Dermatology.

Cordyceps militaris is a medicinal mushroom widely utilized in traditional East Asian medicine, recognized for its diverse therapeutic properties. This review explores the potential of C..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Cordyceps · 2025 · Journal Article · Journal of functional foods

Cultivated Cordyceps militaris exerts anti-allergic effects in a cockroach-induced allergic dermatitis mouse model by suppressing inflammation and enhancing epidermal homeostasis

The study evaluated the anti-allergic effects of ethanol extract derived from laboratory-cultivated Cordyceps militaris (ECM) using the HaCaT cells and cockroach allergen Per a 2-induced allergic dermatitis mouse model..

Immune supportSkin & hydration

High relevance

Enoki · 2025 · Review · Journal of the science of food and agriculture

Effects of Flammulina velutipes powder on the emulsion properties of chicken myofibrillar protein under low-salt conditions.

This study aimed to investigate the influence of varying concentrations of Flammulina velutipes powder (FVP) (0, 4, 8, 12, 16, and 20 g L-1, based on FVP weight per liter of emulsion) on the stability, rheological properties, microstructure, and interfacial protein content of chicken myofibrillar protein (MP)….

Skin & hydration

High relevance

Reishi · 2025 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Enhancement of grindability and physicochemical properties of Ganoderma lucidum through steam explosion and its impact on quality characteristics of wheat dough

Steam explosion (SE) was applied to enhance the grinding performance and physicochemical properties of Ganoderma lucidum (GL), and the effects of steam-exploded Ganoderma lucidum powders (SGL) on quality characteristics of wheat dough were investigated..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Reishi · 2025 · Journal Article · Fitoterapia

Ganoderma lucidum extract reduces skin aging by reducing mitochondrial stress and controlling mitochondrial numbers.

Mitochondrial dysfunction is one of the important signs of cellular and even individual aging. Ganoderma lucidum is a common edible and medicinal mushroom, widely used as a functional food in Asia.

Energy & fatigueSkin & hydration

High relevance

Reishi · 2025 · Journal Article · Journal of ethnopharmacology

Ganoderma lucidum sporoderm-broken spore powder alleviates kidney aging by modulating gut microbiota.

ETHNOPHARMACOLOGICAL RELEVANCE: Ganoderma lucidum (G. lucidum), a revered medicinal mushroom in traditional Chinese medicine (TCM), has been historically documented for its anti-aging properties and nephroprotective effects..

Immune supportGut & microbiomeSkin & hydration

High relevance

Turkey Tail · 2025 · Journal Article · International journal of medicinal mushrooms

Green Synthesis of Silver Nanoparticles by Aqueous Extract of Turkey Tail Medicinal Mushroom Trametes versicolor (Agaricomycetes).

The turkey tail mushroom (Trametes versicolor) is one of the most important medicinal mushrooms because it contains a variety of effective bioactive compounds. This study aimed to produce a novel biomaterial to combat microbial infections without any harmful effects..

Skin & hydration

High relevance

King Oyster · 2025 · Journal Article · International journal of biological macromolecules

High internal phase Pickering emulsions stabilized by Pleurotus eryngii protein-polysaccharide conjugates.

In this work, Pleurotus eryngii protein-polysaccharide conjugates (PE-PPCs) were used as the only stabilizer for the preparation of high internal phase emulsions (HIPEs)..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Shiitake · 2025 · Review · Chemistry & biodiversity

Holistic Evaluation of Shiitake mushrooms (Lentinula edodes): Unraveling Its Medicinal and Therapeutic Potentials.

Lentinula edodes (Shiitake mushroom [SM]), a Basidiomycete with extensive ethnomedicinal use, exhibits significant nutraceutical and pharmaceutical potential. This review critically discusses findings from multidisciplinary sources, including ScienceDirect, PubMed, Scopus, Web of Science, Google Scholar, and classical….

OncologyImmune supportMetabolic healthSkin & hydration

High relevance

Oyster Mushroom · 2025 · Research Article · Molecules (Basel, Switzerland)

Impact of Drying Methods on β-Glucan Retention and Lipid Stability in Oyster Mushroom (Pleurotus ostreatus) Enriched Carp (Cyprinus carpio, L.) Fish Burgers.

BACKGROUND: The incorporation of edible mushrooms into fish-based products offers a promising approach to enhance nutritional quality and oxidative stability. Oyster mushrooms (Pleurotus ostreatus) are valued for their β-glucans and bioactive compounds..

Skin & hydration

High relevance

Cordyceps · 2025 · Journal Article · Sugar tech

Improvement of Cordyceps militaris Polysaccharides Production by a Sole Corn Steep Liquor Medium, and its Antioxidant Activity

The production of polysaccharides through submerged fermentation using a sole corn steep liquor (CSL) medium with Cordyceps militaris (C. militaris GDMCC 5270) has been successfully demonstrated.

Immune supportSkin & hydration

High relevance

Reishi · 2025 · Journal Article · Phytotherapy research: PTR

Inhibition of Hepatoblastoma by Ganoderma Lucidum Polysaccharide via the Induction of HDAC4-p16-RB Axis-Mediated Cellular Senescence.

Hepatoblastoma (HB), the most common primary malignant liver tumor in children, is characterized by high metastatic potential and poor prognosis. Ganoderma lucidum polysaccharide (GLP), the main bioactive compound of Ganoderma lucidum, has not been fully investigated for its therapeutic effects on HB..

OncologyImmune supportLiver supportSkin & hydration

High relevance

Chaga · 2025 · Research Article · Frontiers in pharmacology

Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequencing.

BACKGROUND: Renal fibrosis, characterized by the abnormal accumulation of extracellular matrix in renal tissue and progressive loss of kidney function, is posing a significant challenge in clinical treatment. While several therapeutic options exist, effective treatments remain limited..

Immune supportSkin & hydration

High relevance

Cordyceps · 2025 · Research Article · BMC complementary medicine and therapies

Laboratory cultivated Cordyceps militaris modulates cockroach allergen-induced inflammation in keratinocytes and macrophages dual cell platforms.

BACKGROUND: Cordyceps militaris (CM) is noted for its anti-inflammatory properties and potential efficacy in treating allergic diseases. This research aimed to investigate the anti-inflammatory effect of ethanolic and aqueous extracts from laboratory-cultivated specific Cordyceps militaris on Per a 2-induced….

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Shiitake · 2025 · Journal Article · Food Research International

Mechanisms of formation and consumption of VSCs in thermal dehydration of Lentinula edodes: A transcriptomic analysis utilizing WGCNA

The aroma of Lentinula edodes, primarily attributed to volatile sulfur compounds (VSCs), is a crucial factor influencing its commercial and culinary quality. This study investigated cellular activity and transcriptomic changes during gradient hot-air drying (40–60 °C) at various stages..

Skin & hydration

High relevance

Shiitake · 2025 · Journal Article · Food research international (Ottawa, Ont.)

Mechanisms of formation and consumption of VSCs in thermal dehydration of Lentinula edodes: A transcriptomic analysis utilizing WGCNA.

Skin & hydration

High relevance

Snow Fungus · 2025 · Research Article · Foods (Basel, Switzerland)

Non-Animal Hyaluronic Acid from Tremella fuciformis: A New Source with a Structure and Chemical Profile Comparable to Hyaluronic Acid.

Tremella fuciformis is high in polysaccharides, which have a structure made up of a straight chain of (1→3) α-D-mannan and side chains of glucuronic acid, xylose, and fucose..

Immune supportSkin & hydration

High relevance

Cordyceps · 2025 · Research Article · Journal of cosmetic dermatology

Potential Cosmetic Applications of the Combined Extract of Panax ginseng, Ganoderma lucidum, Cordyceps militaris, and Several Asian Plants.

OBJECTIVE: Although bioactive compounds from single herbs are extensively explored in cosmetics, the synergistic potential of herbal combinations remains understudied..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Reishi · 2025 · Journal Article · Food Bioscience

Preparation of novel Ganoderma lucidum protein-derived bioactive peptides and their oxidation resistance, melanin synthesis inhibition and anti-inflammatory functions

As a key active component in Ganoderma lucidum, the preparation and biological activities of Ganoderma lucidum immunomodulatory protein (rFIP-glu) have been reported, but its deep utilization, such as the preparation of bioactive peptides, has not been explored..

Immune supportGut & microbiomeSkin & hydration

High relevance

Reishi · 2025 · Review · Pharmaceutics

Recent Advances in the Use of Ganoderma lucidum and Coriolus versicolor Mushrooms to Enhance the Anticancer Efficacy of EGFR-Targeted Drugs in Lung Cancer.

Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) is the major subtype, accounting for more than 85% of all lung cancer cases..

OncologyImmune supportSkin & hydrationRespiratory

High relevance

Turkey Tail · 2025 · Research Article · Microbial cell factories

Studies on the treatment of anaerobically digested sludge by white-rot fungi: evaluation of the effect of Phanerochaete chrysosporium and Trametes versicolor.

BACKGROUND: The composition of anaerobically digested sludge is inherently complex, enriched with structurally complex organic compounds and nitrogenous constituents, which are refractory to biodegradation. These characteristics limit the subsequent rational utilization of resources from anaerobically digested sludge..

Energy & fatigueGut & microbiomeSkin & hydration

High relevance

Reishi · 2025 · Research Article · Discover oncology

Systematic network pharmacology and experimental validation reveal anti-glioma mechanisms of ganoderma lucidum via multi-target regulation.

BACKGROUND: Glioma is the most common and lethal primary brain tumor with limited therapeutic options and poor prognosis. Traditional Chinese medicine (TCM) offers a promising avenue for discovering multi-target agents against complex diseases..

OncologyCognition & nervesGut & microbiomeSkin & hydration

High relevance

Chaga · 2025 · Journal Article · Food Biophysics

Ultrasound-Assisted Treatment from Inonotus obliquus Polysaccharides: Extraction Optimization, Structures and Antioxidant Activity

This study examined the effect of sonication conditions on the extraction rate of Inonotus obliquus polysaccharides (IOPs) through a single-factor experiment. Meanwhile, the Box-Behnken design was utilized to optimize the sonication-assisted extraction technology..

Immune supportSkin & hydration

High relevance

Reishi · 2025 · Review · 3 Biotech

Unlocking the therapeutic potential of bioactive compounds in Ganoderma lucidum: a new frontier in natural medicine.

Ganoderma lucidum (Reishi), a valued medicinal fungus used in traditional medicine for over 2000 years, has sparked widespread scientific attention due to its extensive range of bioactive ingredients and therapeutic promise in modern medicine. This study presents a detailed and up-to-date examination of G..

OncologyImmune supportCognition & nervesSkin & hydration

High relevance

Maitake · 2024 · Journal Article · International journal of biological macromolecules

A novel angiotensin I-converting enzyme inhibitory peptide APPLRP from Grifola frondosa ameliorated the Ang II-induced vascular modeling in zebrafish model by mediating smooth muscle cells.

Grifola frondosa has garnered significant popularity as an edible mushroom attributable to its exceptional taste and nutritional benefits. This study isolated APPLRP, a potent ACE-inhibitory peptide, from the alcohol-soluble fraction of Grifola frondosa..

Energy & fatigueMetabolic healthGut & microbiomeSkin & hydration

High relevance

Almond Mushroom · 2024 · Research Article · International journal of molecular sciences

Anti-Photodamage Effect of Agaricus blazei Murill Polysaccharide on UVB-Damaged HaCaT Cells.

UVB radiation is known to induce photodamage to the skin, disrupt the skin barrier, elicit cutaneous inflammation, and accelerate the aging process. Agaricus blazei Murill (ABM) is an edible medicinal and nutritional fungus..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

King Oyster · 2024 · Journal Article · International journal of biological macromolecules

Antibacterial and hemostatic chitin sponge directly constructed from Pleurotus Eryngii via top-down approach.

Chitin, the second most abundant polysaccharide on earth, possesses unique characteristics, including biosafety, biodegradability, and procoagulant activity, making it an attractive material for hemostasis. However, the conventional bottom-up construction of chitin-based materials is intricate and time-consuming..

Immune supportCognition & nervesLiver supportSkin & hydration

High relevance

Cordyceps · 2024 · Research Article · Journal of microbiology and biotechnology

Characterization, Antioxidant Capacity and Protective Effect of Peptides from Cordyceps militaris Cultivated with Tussah Pupa on Oxidative Injured HepG2 Cells.

The antioxidant capacity and protective effect of peptides from protein hydrolysate of Cordyceps militaris cultivated with tussah pupa (ECPs) on H2O2-injured HepG2 cells were studied. Results indicated ECP1 (<3 kDa) presented the strongest antioxidant activity compared with other molecular weight peptides..

OncologySkin & hydration

High relevance

Cordyceps · 2024 · Research Article · BMC genomics

Combined metabolome and transcriptome analysis reveal the mechanism of water stress in Ophiocordyceps sinensis.

BACKGROUND: Ophiocordyceps sinensis (O. sinensis) is the dominant bacterium in the asexual stage of Chinese cordyceps, and its growth usually suffers from water stress.

Energy & fatigueMetabolic healthSkin & hydration

High relevance

Oyster Mushroom · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Comparative Analysis of Freeze-Dried Pleurotus ostreatus Mushroom Powders on Probiotic and Harmful Bacteria and Its Bioactive Compounds.

Pleurotus ostreatus (oyster mushroom) holds excellent promise worldwide, bringing several opportunities and augmenting the tool sets used in the biotechnology field, the food industry, and medicine. Our study explores the antimicrobial and probiotic growth stimulation benefits of freeze-dried P..

Immune supportGut & microbiomeSkin & hydration

High relevance

Shiitake · 2024 · Journal Article · Journal of the science of food and agriculture

Effect of postharvest storage time on quality characteristics of explosion puffing dried whole shiitake mushroom (Lentinula edodes) crisps.

BACKGROUND: Non-fried shiitake mushroom (Lentinula edodes) crisps fabricated by explosion puffing drying (EPD) are receiving worldwide attention because of their crispness, convenience, nutrition and health functions. The quality of mushroom crisps varies with storage time of fresh L.

Skin & hydration

High relevance

Shiitake · 2024 · Research Article · Foods (Basel, Switzerland)

Effects of Balsa Fish Skin Gelatin, Lentinula edodes Mushrooms, Soy Protein Isolate, and Starch on the Sensory Quality and Characterization of Physicochemical and Antioxidant Properties of New Sausage.

Sausages are loved by people for their unique texture, satisfying chewiness, and pleasant flavor. However, in the production of sausages, red meat and a large amount of fat are mainly used, and long-term consumption will increase the risk of diseases such as obesity, heart disease, hypertension, and cancer..

OncologyEnergy & fatigueMetabolic healthSkin & hydration