MycoData

OncologyImmune supportSkin & hydration

Reishi · 2024 · Journal Article · International journal of molecular sciences

Exploring Senolytic and Senomorphic Properties of Medicinal Plants for Anti-Aging Therapies.

Senolytic and senomorphic therapies have gained more and more attention in the last decade. This kind of therapy is based on the killing of cellular senescent cells without harming the "normal" cells.

Immune supportMetabolic healthLiver supportSkin & hydration

Shiitake · 2024 · Journal Article · International journal of biological macromolecules

Lentinan-loaded GelMA hydrogel accelerates diabetic wound healing through enhanced angiogenesis and immune microenvironment modulation.

Diabetic wound healing is a substantial clinical challenge, characterized by delayed angiogenesis and unresolved inflammation. Lentinan, a polysaccharide extracted from shiitake mushrooms, has the potential to regulate both macrophage polarization and angiogenesis, though this aspect remains inadequately explored..

OncologyImmune supportGut & microbiomeSkin & hydration

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Structural clarification of mannoglucan GSBP-2 from Ganoderma sinense and its effects on triple-negative breast cancer migration and invasion.

Ganoderma sinense, known as Lingzhi in China, is a medicinal fungus with anti-tumor properties. Herein, crude polysaccharides (GSB) extracted from G.

Lion's Mane · 2023 · Preprint · journal metadata

Eco-friendly Oxidized Microcrystalline Cellulose/Quaternized Chitosan/Gelatin Hydrogels based on Schiff-base Reaction as Wound Dressing and Naringin Release Kinetic

Abstract Use of by-product waste from farm products to prepare clinical dressings is a resource-saving and eco-friendly approach. In this research, a series of pH-sensitive hydrogels composited with oxidized microcrystalline celluloseisolated from pineapple peel, quaternized chitosan isolated from hericium erinaceus….

Shiitake · 2023 · Letter · International journal of dermatology

Shiitake dermatitis: a case report of a rare mushroom-induced dermatitis in the United States.

Metadata-grounded summary: This letter indexes research on Lentinula edodes in International journal of dermatology in 2023. MycoData maps the paper to skin & hydration based on its title, species context, article metadata, and study classification..

Shiitake · 2023 · Letter · International journal of dermatology

Shiitake dermatitis: clinical forms of presentation.

Shiitake · 2023 · Case Reports · The New England journal of medicine

Shiitake Dermatitis.

Metadata-grounded summary: This case reports indexes research on Lentinula edodes in The New England journal of medicine in 2023. MycoData maps the paper to skin & hydration based on its title, species context, article metadata, and study classification..

Turkey Tail · 2022 · Preprint · journal metadata

Investigation of the Usage Potential of Enzyme-linked Polymers in Different Morphological Structures for the Removal of Micropollutant From Leather Waste Water

Abstract Increasing numbers of chemical elements that are presenting very important problems, are threaten for the environmental health today. The big part of the pollution load in aquatic systems occurred from industrial wastes..

Shiitake · 2021 · Case Reports · Atencion primaria

Flagellate dermatitis secondary to intake shiitake mushrooms.

Metadata-grounded summary: This case reports indexes research on Lentinula edodes in Atencion primaria in 2021. MycoData maps the paper to skin & hydration based on its title, species context, article metadata, and study classification..

Shiitake · 2021 · Case Reports · Dermatitis: contact, atopic, occupational, drug

Lentinan Dermatitis: Time to Rename Shiitake Dermatitis.

Metadata-grounded summary: This case reports indexes research on Lentinula edodes in Dermatitis: contact, atopic, occupational, drug in 2021. MycoData maps the paper to skin & hydration based on its title, species context, article metadata, and study classification..

OncologyImmune supportCognition & nervesSkin & hydration

Cordyceps · 2021 · Review · Molecules (Basel, Switzerland)

The Role of Autophagy in Anti-Cancer and Health Promoting Effects of Cordycepin.

Cordycepin is an adenosine derivative isolated from Cordyceps sinensis, which has been used as an herbal complementary and alternative medicine with various biological activities..

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Comparing the Cosmetic Effects of Liquid-Fermented Culture of Some Medicinal Mushrooms Including Antioxidant, Moisturizing, and Whitening Activities.

There have been few studies on the cosmetic efficacy of Coprinus comatus, Cordyceps militaris, and Pleurotus geesteranus. This article aims to compare the cosmetic effects of the mycelium, fermentation broth, and mycelium and fermentation broth mixture of liquid-fermented C.

Metabolic healthGut & microbiomeLiver supportSkin & hydration

Shiitake · 2018 · Journal Article · Food & function

Effect of traditional and modern culinary processing, bioaccessibility, biosafety and bioavailability of eritadenine, a hypocholesterolemic compound from edible mushrooms.

Eritadenine is a hypocholesterolemic compound that is found in several mushroom species such as Lentinula edodes, Marasmius oreades, and Amanita caesarea (1.4, 0.7 and 0.6 mg per g dry weight, respectively)..

Immune supportGut & microbiomeLiver supportSkin & hydration

King Oyster · 2016 · Journal Article · ACS applied materials & interfaces

Prolonged Three-Dimensional Co-Delivery of Yamanaka Factors for Cell Reprogramming.

Reprogramming somatic cells into a pluripotent state has been widely investigated in two-dimensional (2D) systems but not described in the more biologically faithful three-dimensional (3D) scaffolds..

Lion's Mane · 2025 · Data Paper · Data in brief

Data-driven high-performance liquid chromatography method for the simultaneous analysis of disodium guanylate and disodium inosinate in mushrooms.

With the growing demand for high-throughput analyses that can detect diverse molecules with varying physicochemical properties in shorter times, researchers are increasingly focused on developing or modifying analytical methods..

Lion's Mane · 2025 · Brief Report · Biophysical reports

Scanning electron microscopy of hyphal ectobiont bacteria within mycelial extracellular matrices.

Fungi and bacteria are found living in a wide variety of environments, and their interactions are important in many processes including soil health, human and animal physiology, and in biotechnological applications..

Immune supportCognition & nervesSkin & hydration

Lion's Mane · 2024 · Research Support, Non U.S. Gov'T · Biochemical and biophysical research communications

Hericenone C attenuates the second phase of formalin-induced nociceptive behavior by suppressing the accumulation of CD11c-positive cells in the paw epidermis via phosphorylated P65.

Hericenone C is one of the most abundant secondary metabolites derived from Hericium erinaceus, under investigation for medicinal properties. Here, we report that Hericenone C inhibits the second phase of formalin-induced nociceptive behavior in mice..

Reishi · 2024 · Brief Report · Pharmaceuticals (Basel, Switzerland)

Selective Antineoplastic Potential of Fractionated Caribbean Native Ganoderma Species Extracts on Triple-Negative Breast Cancer Cells.

Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by the absence of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor type 2 expression..

Turkey Tail · 2023 · Journal Article · Enzyme and microbial technology

Enzymatic route for selective glycerol oxidation using covalently immobilized laccases.

Glycerol is an important starting material for the synthesis of many chemical compounds and its selective oxidation represents an efficient way to produce value-added compounds..

OncologyImmune supportSkin & hydration

Reishi · 2023 · Journal Article · Molecules (Basel, Switzerland)

Evaluating the Application Potential of a Recombinant Ganoderma Protein as Bioactive Ingredients in Cosmetics.

The aim of this study was to evaluate the application potential of a recombinant fungal immunomodulatory protein from Ganoderma lucidum (rFIP-glu). First, a recombinant plasmid pPIC9K::FIP-glu-His was transferred into Pichia pastoris for the production of protein..

Turkey Tail · 2023 · Research Article · 3 Biotech

Fusel oil reaction in pressurized water: characterization and antimicrobial activity.

UNLABELLED: This work aimed to investigate the reaction of fusel oil (FO) with pressurized water in a continuous flow reactor, in order to verify the effect of operating conditions (temperature and alcohol to water ratio) on the formation of reaction products, as well as to potentiate the antimicrobial activity of FO..

OncologyEnergy & fatigueSkin & hydration

Reishi · 2023 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Ganoderenic acid D-loaded functionalized graphene oxide-based carrier for active targeting therapy of cervical carcinoma.

Ganoderenic acid D (GAD), extracted from the Chinese herb Ganoderma lucidum, was loaded onto a graphene oxide-polyethylene glycol-anti-epidermal growth factor receptor (GO-PEG-EGFR) carrier to develop a targeting antitumor nanocomposite (GO-PEG@GAD)..

Metabolic healthSkin & hydration

Reishi · 2023 · Journal Article · International journal of medicinal mushrooms

Mushroom-Related Ethnomycological, Ethnomedical, and Socio-Economic Practices in Nigeria.

Native mushrooms are valuable non-timber forest products used worldwide, although they are under-exploited in Africa. This study focused on evaluating ethnomycological practices in Nigeria.

Reishi · 2023 · Journal Article · Frontiers in bioengineering and biotechnology

Mycelium-based biomaterials as smart devices for skin wound healing.

Introduction: Recently, mycelia of Ganoderma lucidum and Pleurotus ostreatus, edible fungi, have been characterized in vitro as self-growing biomaterials for tissue engineering since they are constituted of interconnected fibrous networks resembling the dermal collagen structure..

Oyster Mushroom · 2023 · Journal Article · International journal of medicinal mushrooms

Phenolic Content, Antibacterial and Antioxidant Potential of Several Edible Agaricomycetes Mushrooms Sold in Public Bazaar in Bolu, Turkey.

Edible mushrooms are important natural foods that have been used since ancient times due to their delicious taste, high nutritional value, and various biological activities..

Energy & fatigueGut & microbiomeSkin & hydration

Lion's Mane · 2023 · Research Article · Polymers

Physicochemical Characterization and Antimicrobial Analysis of Vegetal Chitosan Extracted from Distinct Forest Fungi Species.

The main goal of this investigation is to conduct a thorough analysis of the physical, chemical, and morphological characteristics of chitosan derived from various forest fungi. Additionally, the study aims to determine the effectiveness of this vegetal chitosan as an antimicrobial agent..

Gut & microbiomeSkin & hydration

Reishi · 2023 · Journal Article · Nature materials

Three-dimensional printing of mycelium hydrogels into living complex materials.

Biological living materials, such as animal bones and plant stems, are able to self-heal, regenerate, adapt and make decisions under environmental pressures. Despite recent successful efforts to imbue synthetic materials with some of these remarkable functionalities, many emerging properties of complex adaptive….

Turkey Tail · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Biological Synthesis of Monodisperse Uniform-Size Silver Nanoparticles (AgNPs) by Fungal Cell-Free Extracts at Elevated Temperature and pH.

Fungi's ability to convert organic materials into bioactive products offers environmentally friendly solutions for diverse industries. In the nanotechnology field, fungi metabolites have been explored for green nanoparticle synthesis..

Reishi · 2022 · Journal Article · Journal of fungi (Basel, Switzerland)

Fungal-Modified Lignin-Enhanced Physicochemical Properties of Collagen-Based Composite Films.

Renewable and biodegradable materials have attracted broad attention as alternatives to existing conventional plastics, which have caused serious environmental problems. Collagen is a potential material for developing versatile film due to its biosafety, renewability, and biodegradability..

Reishi · 2022 · Journal Article · Aging cell

Ganoderic acid D prevents oxidative stress-induced senescence by targeting 14-3-3ε to activate CaM/CaMKII/NRF2 signaling pathway in mesenchymal stem cells.

Stem cell senescence is an important cause of aging. Delaying senescence may present a novel way to combat aging and age-associated diseases.

OncologyEnergy & fatigueLiver supportSkin & hydration

Chaga · 2022 · Research Article · Experimental and therapeutic medicine

Inonotsuoxide B suppresses hepatic stellate cell activation and proliferation via the PI3K/AKT and ERK1/2 pathway.

Hepatic stellate cells (HSCs) serve a pivotal role in the formation and degradation of the extracellular matrix during liver fibrosis. Inonotsuoxide B is a tetracyclic triterpenoid that can be extracted from Inonotus obliquus and has been previously reported to inhibit the growth of liver and gastric cancer cells..

Turkey Tail · 2022 · Research Article · International journal of molecular sciences

Laccase Mediator Cocktail System as a Sustainable Skin Whitening Agent for Deep Eumelanin Decolorization.

The overproduction of eumelanin leads to a panel of unaesthetic hyper-pigmented skin diseases, including melasma and age spots. The treatment of these diseases often requires the use of tyrosinase inhibitors, which act as skin whitening agents by inhibiting the synthesis of eumelanin, with harmful side effects..

Oyster Mushroom · 2021 · Journal Article · Scientific reports

Advanced mycelium materials as potential self-growing biomedical scaffolds.

Mycelia, the vegetative part of fungi, are emerging as the avant-garde generation of natural, sustainable, and biodegradable materials for a wide range of applications..

Immune supportCognition & nervesSkin & hydration

Niu-Chang-Chih · 2021 · Research Article · Molecules (Basel, Switzerland)

Ergosta-7,9(11),22-trien-3β-ol Rescues AD Deficits by Modulating Microglia Activation but Not Oxidative Stress.

Ergosta-7,9(11),22-trien-3β-ol (EK100) was isolated from the Taiwan-specific medicinal fungus Antrodia camphorata, which is known for its health-promotion and anti-aging effects in folk medicine. Alzheimer's disease (AD) is a major aging-associated disease..

Shiitake · 2021 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Harnessing the potential of UVB irradiation for improving the nutraceutical properties of edible xylotrophic mushroom dried powder

The present study aimed at optimizing the parameters for increasing vitamin D₂ content along with other nutraceutical properties (β-glucans, antioxidants, total phenols, flavonoids, and amino acid contents) in dried mushroom Lentinula edodes (L. edodes) powder using ultraviolet B (UVB) irradiation..

Mesima · 2021 · Research Article · Molecules (Basel, Switzerland)

Hispolon Induces Apoptosis, Suppresses Migration and Invasion of Glioblastoma Cells and Inhibits GBM Xenograft Tumor Growth In Vivo.

Hispolon, a polyphenol compound isolated from Phellinus linteus, has been reported to exhibit antioxidant, antiproliferative, and antitumor activities. This study aimed to explore the antitumor effects of hispolon on glioblastoma multiforme (GBM) cells in vitro and in vivo..

Turkey Tail · 2021 · Research Article · Polymers

Laccase-Mediator System Using a Natural Mediator as a Whitening Agent for the Decolorization of Melanin.

In this study, a laccase-mediator system (LMS) using a natural mediator was developed as a whitening agent for melanin decolorization. Seven natural mediators were used to replace synthetic mediators and successfully overcome the low redox potential of laccase and limited access of melanin to the active site of….

Turkey Tail · 2021 · Journal Article · Biotechnology letters

Mycelial culture extracts of selected wood-decay mushrooms as a source of skin-protecting factors

OBJECTIVES: This study analyzed the content of substances with cosmetologic properties in the extracts obtained from the mycelial cultures of Ganoderma applanatum, Laetiporus sulphureus, and Trametes versicolor..

Turkey Tail · 2021 · Research Article · Biotechnology letters

Mycelial culture extracts of selected wood-decay mushrooms as a source of skin-protecting factors.

Oyster Mushroom · 2021 · Journal Article · Molecules (Basel, Switzerland)

On the Identification and Quantification of Ergothioneine and Lovastatin in Various Mushroom Species: Assets and Challenges of Different Analytical Approaches.

In recent years, mushrooms have drawn the attention of agro-industries and food-industries as they were considered to be valuable natural sources of health promoting compounds such as β-glucans, ergothioneine, and lovastatin..

Immune supportMetabolic healthSkin & hydration

Almond Mushroom · 2023 · Research Support, Non U.S. Gov'T · Stem cells and development

Effect of Insulin on Bone Formation Ability of Rat Alveolar Bone Marrow Mesenchymal Stem Cells.

The alveolar bone marrow mesenchymal stem cells (ABM-MSCs) play an important role in oral bone healing and regeneration. Insulin is considered to improve impaired oral bones due to local factors, systemic factors and pathological conditions..

Skin & hydrationRespiratory

Almond Mushroom · 2023 · Research Support, Non U.S. Gov'T · Acta biomaterialia

Epithelial folding of alveolar cells derived from human induced pluripotent stem cells on artificial basement membrane.

Epithelial folding depends on mechanical properties of both epithelial cells and underlying basement membrane (BM). While folding is essential for tissue morphogenesis and functions, it is difficult to recapitulate features of a growing epithelial monolayer for in vitro modeling due to lack of in vivo like BM..

OncologyImmune supportMetabolic healthSkin & hydration

Almond Mushroom · 2023 · Research Support, Non U.S. Gov'T · Cancer communications (London, England)

Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.

BACKGROUND: Trastuzumab is a first-line targeted therapy for human epidermal growth factor receptor-2 (HER2)-positive gastric cancer. However, the inevitable occurrence of acquired trastuzumab resistance limits the drug benefit, and there is currently no effective reversal measure..

Skin & hydrationRespiratory

Almond Mushroom · 2022 · Research Support, Non U.S. Gov'T · Advanced healthcare materials

Generation of Alveolar Epithelium Using Reconstituted Basement Membrane and hiPSC-Derived Organoids.

In vitro modeling of alveolar epithelium needs to recapitulate features of both cellular and noncellular components of the lung tissues. Herein, a method is presented to generate alveolar epithelium by using human induced pluripotent stem cells (hiPSCs) and reconstituted or artificial basement membrane (ABM)..

Immune supportGut & microbiomeSkin & hydration

Almond Mushroom · 2021 · Research Support, Non U.S. Gov'T · Stem cells and development

Effects of rhBMP-2 on Bone Formation Capacity of Rat Dental Stem/Progenitor Cells from Dental Follicle and Alveolar Bone Marrow.

Dental stem/progenitor cells are a promising cell sources for alveolar bone (AB) regeneration because of their same embryonic origin and superior osteogenic potential. However, their molecular processes during osteogenic differentiation remain unclear..

Almond Mushroom · 2021 · Research Support, Non U.S. Gov'T · PloS one

The multivariate approach identifies relationships between pre-slaughter factors, body lesions, ham defects and carcass traits in pigs.

Abattoir meat inspection has been proposed for the collection of welfare outcomes. The identification of suitable animal-based measures (ABM) is still a critical point that needs to be implemented to avoid collinearity among measures..

Shiitake · 2020 · Journal Article · Internal medicine (Tokyo, Japan)

Shiitake Dermatitis.

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Internal medicine (Tokyo, Japan) in 2020. MycoData maps the paper to skin & hydration based on its title, species context, article metadata, and study classification..

Shiitake · 2018 · Journal Article · La Revue du praticien

[Shiitake dermatitis].

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in La Revue du praticien in 2018. MycoData maps the paper to skin & hydration based on its title, species context, article metadata, and study classification..

Shiitake · 2018 · Journal Article · International journal of medicinal mushrooms

Purification and Antithrombotic Potential of a Fibrinolytic Enzyme from Shiitake Culinary- Medicinal Mushroom, Lentinus edodes GNA01 (Agaricomycetes).

We purified Lentinus edodes GNA01 fibrinolytic enzyme (LEFE) and identified it as a novel metalloprotease. LEFE was purified to homogeneity through a 2-step procedure, with an 8.28-fold increase in specific activity and 5.3% recovery..