MycoData

Cognition & nervesRespiratory

Almond Mushroom · 2022 · Journal Article · Advanced theory and simulations

When Do We Need Massive Computations to Perform Detailed COVID-19 Simulations?

The COVID-19 pandemic has infected over 250 million people worldwide and killed more than 5 million as of November 2021. Many intervention strategies are utilized (e.g., masks, social distancing, vaccinations), but officials making decisions have a limited time to act..

Cognition & nervesEnergy & fatigueLiver support

Almond Mushroom · 2021 · Research Article · Learning health systems

A collaborative learning health system agent-based model: Computational and face validity.

INTRODUCTION: Improving the healthcare system is a major public health challenge. Collaborative learning health systems (CLHS) - network organizations that allow all healthcare stakeholders to collaborate at scale - are a promising response..

Almond Mushroom · 2021 · Journal Article · International journal of behavioral medicine

A Cross-sectional Study of Attention Bias for Facial Expression Stimulation in Patients with Stroke at the Convalescence Stage.

BACKGROUND: Post-stroke depression increases the likelihood of adverse physical symptoms. Attentional bias (AB) for negative stimuli is important in depression onset, maintenance, and remission.

OncologyImmune supportCognition & nervesRespiratory

Almond Mushroom · 2021 · Journal Article · Cancers

An Agent-Based Model of Combination Oncolytic Viral Therapy and Anti-PD-1 Immunotherapy Reveals the Importance of Spatial Location When Treating Glioblastoma.

Oncolytic viral therapies and immunotherapies are of growing clinical interest due to their selectivity for tumor cells over healthy cells and their immunostimulatory properties..

Cognition & nervesEnergy & fatigueMetabolic health

Almond Mushroom · 2021 · Research Article · Frontiers in microbiology

Application of Machine Learning Techniques to an Agent-Based Model of Pantoea.

Agent-based modeling (ABM) is a powerful simulation technique which describes a complex dynamic system based on its interacting constituent entities. While the flexibility of ABM enables broad application, the complexity of real-world models demands intensive computing resources and computational time; however, a….

Almond Mushroom · 2021 · Research Article · Proceedings. Mathematical, physical, and engineering sciences

Bayesian uncertainty quantification for data-driven equation learning.

Equation learning aims to infer differential equation models from data. While a number of studies have shown that differential equation models can be successfully identified when the data are sufficiently detailed and corrupted with relatively small amounts of noise, the relationship between observation noise and….

Almond Mushroom · 2021 · Research Article · Frontiers in bioengineering and biotechnology

Development and Characterization of a Biomimetic Totally Implantable Artificial Basilar Membrane System.

Cochlear implants (CIs) have become the standard treatment for severe-to-profound sensorineural hearing loss. Conventional CIs have some challenges, such as the use of extracorporeal devices, and high power consumption for frequency analysis..

Almond Mushroom · 2021 · Journal Article · Frontiers in robotics and AI

Drivers of Automation and Consequences for Jobs in Engineering Services: An Agent-Based Modelling Approach.

New technology is of little use if it is not adopted, and surveys show that less than 10% of firms use Artificial Intelligence. This paper studies the uptake of AI-driven automation and its impact on employment, using a dynamic agent-based model (ABM)..

Almond Mushroom · 2021 · Research Article · Current opinion in behavioral sciences

Improving autobiographical memory in Alzheimer's disease by transcranial alternating current stimulation.

We review the latest evidence from animal models, studies in humans using electrophysiology, experimental memory paradigms, and non-invasive brain stimulation (NIBS), in the form of transcranial alternating current stimulation (tACS), suggesting that the altered activity in networks that contribute to the….

Almond Mushroom · 2021 · Journal Article · BMC psychiatry

Influence of established and subjectively perceived as well as evaluated individual characteristics on the utilization of mental health services among individuals with depressive disorders: protocol of a longitudinal study examining how to supplement the "behavioral model of health services use" and on need-congruent use of mental health services.

BACKGROUND: Approximately one out of every three people in Germany who meets the diagnostic criteria for major depression has contact with mental health services. Therefore, according to treatment guidelines, two thirds of all individuals with depression are insufficiently treated..

Cognition & nervesEnergy & fatigueLiver support

Almond Mushroom · 2021 · Research Article · Neuroimage. Reports

No change in electrocortical measures of performance monitoring in high trait anxious individuals following multi-session attention bias modification training.

Heightened attentional bias to threat and enhanced performance monitoring have been linked to higher levels of anxiety. Attentional bias modification (ABM) was developed to reduce attentional bias to threat and thus reduce anxiety..

Cognition & nervesMetabolic healthRespiratory

Almond Mushroom · 2021 · Journal Article · European journal of pediatrics

Pediatric subdural empyema as a complication of meningitis: could CSF protein/CSF glucose ratio be used to screen for subdural empyema?

Subdural empyema (SDE) is a rare condition which can appear secondary to meningitis in childhood, especially in infants. This study was planned to evaluate and compare clinical and laboratory features, treatment, and outcome of children with SDE to those with acute bacterial meningitis (ABM) without SDE..

OncologyCognition & nervesRespiratory

Almond Mushroom · 2021 · Journal Article · Therapeutic advances in medical oncology

Phase III randomized study of carboplatin pemetrexed with or without bevacizumab with initial versus "at progression" cerebral radiotherapy in advanced non squamous non-small cell lung cancer with asymptomatic brain metastasis.

BACKGROUND: The role and timing of whole or stereotaxic brain radiotherapy (BR) in patients with advanced non-small cell lung cancer (aNSCLC) and asymptomatic brain metastases (aBMs) are not well established..

Almond Mushroom · 2021 · Journal Article · Infectious diseases (London, England)

Serum levels of neurofilament light chain, neuron-specific enolase and S100 calcium-binding protein B during acute bacterial meningitis: a prospective cohort study.

PURPOSE: Acute bacterial meningitis (ABM) is a severe disease with an overall poor outcome. Neurofilament (NFL) has shown to be a promising biomarker of neuroaxonal injury in various neurological disorders but has not been investigated in ABM..

Almond Mushroom · 2021 · Journal Article · Frontiers in physiology

The Use of Artificial Neural Networks to Forecast the Behavior of Agent-Based Models of Pathophysiology: An Example Utilizing an Agent-Based Model of Sepsis.

Introduction: Disease states are being characterized at finer and finer levels of resolution via biomarker or gene expression profiles, while at the same time. Machine learning (ML) is increasingly used to analyze and potentially classify or predict the behavior of biological systems based on such characterization..

Almond Mushroom · 2021 · Research Article · Frontiers in physiology

Utilizing the Heterogeneity of Clinical Data for Model Refinement and Rule Discovery Through the Application of Genetic Algorithms to Calibrate a High-Dimensional Agent-Based Model of Systemic Inflammation.

Introduction: Accounting for biological heterogeneity represents one of the greatest challenges in biomedical research. Dynamic computational and mathematical models can be used to enhance the study and understanding of biological systems, but traditional methods for calibration and validation commonly do not account….

Almond Mushroom · 2021 · Research Article · Cognitive therapy and research

What's in a Face? Amygdalar Sensitivity to an Emotional Threatening Faces Task and Transdiagnostic Internalizing Disorder Symptoms in Participants Receiving Attention Bias Modification Training.

BACKGROUND: Altered amygdala activation in response to the emotional matching faces (EMF) task, a task thought to reflect implicit emotion detection and reactivity, has been found in some patients with internalizing disorders; mixed findings from the EMF suggest individual differences (within and/or across diagnoses)….

OncologyImmune supportCognition & nervesMetabolic health

Almond Mushroom · 2011 · Research Article · Journal of clinical biochemistry and nutrition

Ipomoea batatas and Agarics blazei ameliorate diabetic disorders with therapeutic antioxidant potential in streptozotocin-induced diabetic rats

Ipomoea batatas, Agaricus blazei and Smallanthus sonchifolius are known to favorably influence diabetes mellitus. To clarify their antidiabetic efficacy and hypoglycemic mechanisms, we treated streptozotocin-induced diabetic rats with daily oral feeding of powdered Ipomoea batatas (5 g kg(-1) d(-1)), Agaricus blazei….

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Developmental and comparative immunology

Immulectin-2 from the ghost moth, Thitarodes xiaojinensis (Lepidoptera: Hepialidae), modulates cellular and humoral responses against fungal infection.

C type-lectins constitute a large family of pattern recognition receptors, playing important roles in insect immune defenses. Thitarodes xiaojinensis larvae showed distinct immune features after Ophiocordyceps sinensis, Cordyceps militaris, or Beauveria bassiana infection..

Immune supportCognition & nervesEnergy & fatigue

Cordyceps · 2021 · Research Support, Non U.S. Gov'T · Neurotoxicology

Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission.

Accumulating evidences suggest that inflammation-mediated neurons dysfunction participates in the initial and development of Parkinson's disease (PD), whereas mitochondria have been recently recognized as crucial regulators in NLRP3 inflammasome activation..

Cognition & nervesMetabolic healthGut & microbiome

Oyster Mushroom · 2021 · Research Support, Non U.S. Gov'T · Toxins

Dissecting Out the Molecular Mechanism of Insecticidal Activity of Ostreolysin A6/Pleurotolysin B Complexes on Western Corn Rootworm.

Ostreolysin A6 (OlyA6) is a protein produced by the oyster mushroom (Pleurotus ostreatus). It binds to membrane sphingomyelin/cholesterol domains, and together with its protein partner, pleurotolysin B (PlyB), it forms 13-meric transmembrane pore complexes..

Lion's Mane · 2005 · Patent · journal metadata

METHOD FOR WATER EXTRACTS OF HERICIUM ERINACEUS, AND SOUP THEREOF

Metadata-grounded summary: This patent indexes research on Hericium erinaceus in 2005. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..

OncologyCognition & nervesLiver support

Niu-Chang-Chih · 2005 · Patent · journal metadata

NEW MIXTURE AND COMPOUND OBTAINED FROM MYCELIUM OF ANTRODIA CAMPHORATA, AND USE THEREOF

Metadata-grounded summary: This patent indexes research on Antrodia camphorata in 2005. MycoData maps the paper to oncology, cognition & nerves, liver support based on its title, species context, article metadata, and study classification..

OncologyCognition & nervesLiver support

Niu-Chang-Chih · 2005 · Patent · journal metadata

NOVEL MIXTURE AND COMPOUNDS FROM MYCELIA OF ANTRODIA CAMPHORATA AND USE THEREOF

OncologyCognition & nervesLiver support

Niu-Chang-Chih · 2005 · Patent · journal metadata

Process for producing a culture of antrodia camphorata and product obtained thereby

Almond Mushroom · 2026 · Preprint · journal metadata

Awareness-Based Meaning System (ABMS): A Valuation-Driven Model of Meaning as Messaging

The question of how meaning arises from communication, cognition, and experience remains unresolved across philosophy and cognitive science. Existing theories variously attribute meaning to intention, linguistic structure, interpretation, or subjective valuation, yet fail to integrate these dimensions into a unified….

Almond Mushroom · 2026 · Preprint · journal metadata

Governing the Mind of the Market: A Yuan Intelligence Framework for Financial Stability in the Age of AI—A Chinese Philosophical Contribution to Global Governance

Abstract This paper introduces “Yuan Intelligence,” a governance paradigm rooted in Chinese generative philosophy, as a novel framework for ensuring financial stability in algorithm‑driven markets..

Cognition & nervesSkin & hydration

Shiitake · 2026 · Preprint · journal metadata

Mimicry of Symptomatic Dermographism: A Case Series of Atypical Presentations

Symptomatic dermographism (SD) is the most common form of chronic inducible urticaria, typically presenting with pruritic, linear wheals that appear within minutes after stroking the skin and resolve within 30 minutes. However, not every linear urticarial eruption following friction or scratching is true SD..

Almond Mushroom · 2026 · Preprint · journal metadata

Simulating Ideological Deadlock: Persona Stability and Conflict Resolution in LLM-Based Multi-Agent Frameworks

Abstract The integration of Large Language Models (LLMs) into Agent-Based Modeling (ABM) has revolutionized the capacity to simulate complex sociopolitical dynamics..

Almond Mushroom · 2025 · Preprint · journal metadata

A Priori recognition for biological phenomena prior to empirical understanding

Biological phenomena include unrecognized events. These unrecognized events often unknowingly increase observer bias, which inhibits open and reproducible science.

OncologyCognition & nerves

Almond Mushroom · 2025 · Preprint · bioRxiv: the preprint server for biology

Astrocyte reprogramming drives tumor progression and chemotherapy resistance in agent-based models of breast cancer brain metastases.

Breast cancer brain metastases (BCBM) affect nearly 90,000 patients annually in the United States and carry a significant risk of mortality. As metastatic lesions develop, the unique milieu of the brain microenvironment shapes disease progression and therapeutic response..

Almond Mushroom · 2025 · Preprint · journal metadata

Leveraging agent-based models and deep reinforcement learning to predict taxis in cell migration: Insights from barotaxis

We present a novel computational framework that combines Agent-Based Modeling (ABM) with Reinforcement Learning (RL) using the Double Deep Q-Network (DDQN) algorithm to determine cellular behavior in response to environmental signals..

Almond Mushroom · 2025 · Preprint · journal metadata

License to Simulate: When Agent-Based Models Are More Fiction Than Function

Agent-based models (ABMs) are increasingly used to study supply chain (SC) systems due to their capacity to capture decentralised behaviour, heterogeneity, and emergent dynamics. However, the mere use of agent-based simulation platforms does not necessarily imply that the models fully exploit the agent-based paradigm..

Almond Mushroom · 2025 · Preprint · journal metadata

Tokenized Incentives and Loyalty: Leveraging Blockchain-Based Smart Contracts for Enhancing Eco-Tourism Behavioral Engagement

Abstract This research investigates ways in which blockchain smart contracts and gamified token rewards can increase eco-tourists' engagement and loyalty to online sustainability practices..

Almond Mushroom · 2024 · Preprint · journal metadata

An Agent-based Modeling Framework for Learning Progression Research in Middle School Mathematics Curriculum

Abstract Large-scale experimental studies on Learning Progression (LP) in middle school mathematics face challenges, such as resource limitations and ethical considerations..

Almond Mushroom · 2024 · Preprint · journal metadata

Attention bias at baseline does not moderate the effect of attention bias modification for depressive symptoms

Background Clinical trials of Attention Bias Modification for depressive symptoms have consistently produced small effect sizes and mixed results. Therefore, identifying subpopulations for whom this intervention works has been called for..

Cognition & nervesRespiratory

Almond Mushroom · 2024 · Preprint · journal metadata

Cost-benefit of Influenza Vaccinations in Frontline Workers: A Dynamic Modelling Study

Influenza significantly impacts public health, particularly among the elderly and those with underlying health conditions, but it also imposes substantial economic and operational burdens on the working-age population..

Immune supportCognition & nervesMetabolic healthLiver support

Chaga · 2024 · Preprint · journal metadata

Liver-X receptor β-selective agonist CE9A215 regulates Alzheimer’s disease- associated pathology in a 3xTg-AD mouse model

Abstract Background In Alzheimer's disease (AD), tau pathology is more closely associated with disease progression. Therefore, the development of agents that alleviate tau pathology is essential..

Immune supportCognition & nervesRespiratory

Almond Mushroom · 2020 · Review · Infection and drug resistance

Management of Acute Bacterial Meningitis in Children.

Acute community-acquired bacterial meningitis (ABM) in children continues to have high rates of neurological morbidity and mortality despite the overall declining rates of infection attributed to the use of vaccines and intrapartum Group B Streptococcus prophylaxis..

OncologyImmune supportCognition & nerves

Maitake · 2017 · Research Support, Non U.S. Gov'T · Journal of evidence-based complementary & alternative medicine

Induction Effect to Apoptosis by Maitake Polysaccharide: Synergistic Effect of Its Combination With Vitamin C in Neuroglioma Cell.

Polysaccharide extracted from the Maitake mushroom (MP) is considered as a potential anticancer agent. The present study was performed to investigate the cytotoxic effects of MP and vitamin C (VC) alone and in combination on the viability of human neuroglioma M059 K cells in vitro..

Maitake · 2016 · Research Support, Non U.S. Gov'T · Scientific reports

The Prefrontal Dectin-1/AMPA Receptor Signaling Pathway Mediates The Robust and Prolonged Antidepressant Effect of Proteo-β-Glucan from Maitake.

Proteo-β-glucan from Maitake (PGM) is a strong immune regulator, and its receptor is called Dectin-1. Cumulative evidence suggests that AMPA receptors are important for the treatment of depression..

OncologyCognition & nerves

Lion's Mane · 2014 · Journal Article · Journal of neurosurgery

The lion's mane sign: surgical results using the bilateral fronto-orbito-nasal approach in large and giant anterior skull base meningiomas.

OBJECT: Concerns about extreme peritumoral edema and its ensuing surgical and perioperative complications led the authors to use the bilateral fronto-orbito-nasal approach to remove midline anterior skull base meningiomas that were larger than 4 cm..

Immune supportCognition & nervesMetabolic healthGut & microbiome

Maitake · 2009 · Research Article · Experimental biology and medicine (Maywood, N.J.)

Maitake beta-glucan enhances umbilical cord blood stem cell transplantation in the NOD/SCID mouse.

Beta glucans are cell wall constituents of yeast, fungi and bacteria, as well as mushrooms and barley. Glucans are not expressed on mammalian cells and are recognized as pathogen-associated molecular patterns (PAMPS) by pattern recognition receptors (PRR)..

Cognition & nervesEnergy & fatigue

Almond Mushroom · 2026 · Research Article · Digital health

A mechanism-based digital intervention for alexithymia: Design, development, and validation of a multi-modal approach.

OBJECTIVE: Alexithymia, characterized by difficulty identifying and describing feelings, coupled with an externally-oriented thinking style, is a transdiagnostic trait associated with various disorders. Despite its prevalence, targeted interventions remain limited..

Almond Mushroom · 2026 · Journal Article · Scientific reports

Enhancing rabies epidemic modeling with neural networks and fractional calculus.

Rabies remains a major public health concern, particularly in regions where dog-mediated transmission sustains human infection risk. Classical rabies models often rely on integer-order dynamics and overlook the long incubation periods and delayed behavioral responses that characterize the disease..

Cognition & nervesEnergy & fatigue

Almond Mushroom · 2026 · Journal Article · Neural networks: the official journal of the International Neural Network Society

Fine-tuning large language models in federated learning with fairness-aware prompt selection.

Large language models (LLMs) require domain-specific fine-tuning for real-world deployment, yet face critical barriers of data privacy and computational constraints..

Cognition & nervesRespiratory

Almond Mushroom · 2026 · Journal Article · Scientific reports

Fixed-point topology meets fractal memory: a Kutumba-stabilized framework for nonlocal fractal-fractional dynamics.

This paper presents an innovative synthesis of generalised fixed-point theory, advanced topological degree methodologies, and high-order computational frameworks for memory-driven dynamical systems..

Cognition & nervesLiver support

Shiitake · 2026 · Journal Article · Environmental monitoring and assessment

Health risk assessment of cadmium exposure via multiple pathways in preschool children from the inland region of Northwest China.

Cadmium (Cd) is a toxic heavy metal that is important to consider because of its health risks to humans. Prolonged exposure to Cd in humans presents significant health hazards, including renal, hepatic, and neurological damage, and may also result in carcinogenic effects..

Reishi · 2026 · Journal Article · IEEE transactions on medical imaging

Intervention-Based Mixup Augmentation for Multiple Instance Learning in Whole-Slide Image Survival Analysis.

In the field of computational pathology, multiple instance learning (MIL) has become a critical modeling framework for analyzing gigapixel whole-slide images (WSIs)..