MycoData

BACKGROUND: PD-L1 blockade has been found to be effective in treating multiple malignancies. Combined therapy is proposed to provide better therapeutic effects.

OncologyImmune supportGut & microbiome

Medium relevance

Cordyceps · 2024 · Journal Article · Viruses

Cordycepin Inhibits Enterovirus A71 Replication and Protects Host Cell from Virus-Induced Cytotoxicity through Adenosine Action Pathway.

Enterovirus A71 (EV-A71) infection typically causes mild illnesses, such as hand-foot-and-mouth disease (HFMD), but occasionally leads to severe or fatal neurological complications in infants and young children. Currently, there is no specific antiviral treatment available for EV-A71 infection..

OncologyCognition & nervesGut & microbiomeRespiratory

Medium relevance

Cordyceps · 2024 · Journal Article · Journal of biochemical and molecular toxicology

Cordycepin inhibits kidney injury by regulating GSK-3β-mediated Nrf2 activation.

We explored the role and mechanism of cordycepin (COR) in inhibiting kidney injury. A mouse model of kidney injury was established using cisplatin (CDDP), and the kidney function, histopathology, and ferroptosis indices in mice were detected after intervening with COR..

Medium relevance

Shiitake · 2024 · Journal Article · Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Cu(II) detection by a fluorometric probe based on thiazoline-amidoquinoline derivative and its application to water and food samples.

Two novel fluorescent probes for Cu2+ detection have been developed based on thiazoline-quinoline conjugates bearing a 4-ethynyl-N,N-dimethylaniline unit (QT1 and QT2)..

Medium relevance

Almond Mushroom · 2024 · Journal Article · International journal of women's health

Current Situation and Mental Health of Pregnant Women During the Prevention and Control of Novel Coronavirus Infection: A Cross-Sectional Study on the Investigation of Influencing Factors.

BACKGROUND: COVID-19 is a highly contagious respiratory infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which became a global public health crisis..

Cognition & nervesRespiratory

Medium relevance

Shiitake · 2024 · Research Article · Gels (Basel, Switzerland)

Development and Characterization of Hybrid Meat Analogs from Whey Protein-Mushroom Composite Hydrogels.

There is a need to reduce the proportion of animal-derived food products in the human diet for sustainability and environmental reasons. However, it is also important that a transition away from animal-derived foods does not lead to any adverse nutritional effects..

Medium relevance

Cordyceps · 2024 · Journal Article · Journal of fungi (Basel, Switzerland)

Development of SCAR Markers for Genetic Authentication of Metarhizium acridum.

In this study, molecular typing using Randomly Amplified Polymorphic DNA (RAPD-PCR) was conducted on 16 original isolates of Metarhizium acridum obtained from locusts (Schistocerca piceifrons ssp. piceifrons.) in Mexico (MX)..

Medium relevance

Shiitake · 2024 · Journal Article · Chemical & pharmaceutical bulletin

Discovery of a Novel Lidocaine Metabolite by Human Liver Microsome and Identification of Microbial Species Which Produces the Same Metabolite.

Preparation of drug metabolites at the milligram scale is essential for determining the structure and toxicity of drug metabolites. However, their preparation using recombinant proteins and human liver microsomes (HLM) is often difficult because of technical and ethical issues..

Metabolic healthLiver support

Medium relevance

Cordyceps · 2024 · Research Article · Nature communications

Early warning of trends in commercial wildlife trade through novel machine-learning analysis of patent filing.

Unsustainable wildlife trade imperils thousands of species, but efforts to identify and reduce these threats are hampered by rapidly evolving commercial markets. Businesses trading wildlife-derived products innovate to remain competitive, and the patents they file to protect their innovations also provide an….

Cognition & nerves

Medium relevance

Shiitake · 2024 · Journal Article · Carbohydrate polymers

Effect of polydimethylsiloxane on the structure and barrier properties of starch/PBAT composite films

This study aimed to investigate the effects of polydimethylsiloxane (PDMS) with a low surface energy on the structure and physicochemical properties of starch/poly (butylene adipate-co-terephthalate) (PBAT) blown films. The film's appearance was not significantly changed after the addition of PDMS..

Energy & fatigue

Medium relevance

Shiitake · 2024 · Journal Article · Carbohydrate polymers

Effect of polydimethylsiloxane on the structure and barrier properties of starch/PBAT composite films.

Energy & fatigue

Medium relevance

Maitake · 2024 · Journal Article · Molecules (Basel, Switzerland)

Effects of a β-Glucan-Rich Blend of Medicinal Mushrooms and Botanicals on Innate Immune Cell Activation and Function Are Enhanced by a Very Low Dose of Bovine Colostrum Peptides.

Nutraceutical immune support offers potential for designing blends with complementary mechanisms of action for robust support of innate immune alertness. We documented enhanced immune activation when bovine colostrum peptides (BC-Pep) were added to an immune blend (IB) containing β-glucans from yeast, shiitake,….

OncologyImmune supportRespiratory

Medium relevance

Cordyceps · 2024 · Journal Article · Veterinary parasitology

Efficacy of cordycepin against Neospora caninum infection in vitro and in vivo.

Neospora caninum (N. caninum) is an obligate intracellular Apicomplexa parasite that causes abortions in dairy cows and incurs substantial to significant economic losses in the global dairy farming industry..

Immune supportMetabolic healthLiver support

Medium relevance

Wood Ear · 2024 · Journal Article · Environmental pollution (Barking, Essex: 1987)

Enhanced immobilization of cadmium and lead in contaminated soil using calcium alginate-modified HAP biochar: Improvements in soil health and microbial diversity.

A novel adsorbent, calcium alginate-modified HAP (Hydroxyapatite)-wood ear mushroom sticks biochar (CA-HAPMB), was synthesized to enhance the immobilization of Cd and Pb in soil..

Medium relevance

Cordyceps · 2024 · Journal Article · Biological control

Enhancement of sporeś dissemination in the combination of entomopathogenic nematodes and fungus

Entomopathogenic nematodes and fungi are organisms that cause epizootics in insect and are therefore important bioagents. Many studies focus on the effectiveness of either entomopathogenic nematodes or fungi for controlling pests, though it has been shown that a combination of the two entomopathogens may enhance their….

Medium relevance

Cordyceps · 2024 · Journal Article · World J Microbiol Biotechnol

Entomopathogenic fungi in crops protection with an emphasis on bioactive metabolites and biological activities

Plant pathogens with their abundance are harmful and cause huge damage to different agricultural crops and economy of a country as well as lead towards the shortage of food for humans..

Medium relevance

Cordyceps · 2024 · Research Article · Insects

Evaluation of Biopesticides for Management of Bemisia tabaci Middle East-Asia Minor 1 (Hemiptera: Aleyrodidae) in Florida.

The sweetpotato whitefly, Bemisia tabaci MEAM1, is a pest known to significantly impact tomato development and yields through direct damage and virus transmission. To manage this pest, the current study compared the effectiveness of various insecticide rotations..

Respiratory

Medium relevance

Reishi · 2024 · Journal Article · International journal of molecular sciences

Exploring Senolytic and Senomorphic Properties of Medicinal Plants for Anti-Aging Therapies.

Senolytic and senomorphic therapies have gained more and more attention in the last decade. This kind of therapy is based on the killing of cellular senescent cells without harming the "normal" cells.

OncologyImmune supportSkin & hydration

Medium relevance

Almond Mushroom · 2024 · Research Article · Children (Basel, Switzerland)

Exploring the Effectiveness and Challenges of Community Rehabilitation Service Programs for Children with Developmental Delays: A Qualitative Study from the Perspective of Early Intervention Service Providers in Taiwan.

This qualitative study aimed to investigate the effectiveness of community rehabilitation programs for children with developmental delays from the perspective of early intervention service providers in Taiwan..

Medium relevance

Nameko · 2024 · Research Article · International journal of molecular sciences

Exploring the Potential of Fungal Biomass for Bisphenol A Removal in Aquatic Environments.

Bisphenol A is a plastic component, which shows endocrine activity that is detrimental to humans and aquatic ecosystems. The elimination of BPA from the environment is one of the solutions for BPA contaminant management..

Immune support

Medium relevance

Almond Mushroom · 2024 · Research Article · Entropy (Basel, Switzerland)

Exploring the Role of Genetic and Environmental Features in Colorectal Cancer Development: An Agent-Based Approach.

The complexity of issues in cancer research has led to the introduction of powerful computational tools to help experimental in vivo and in vitro methods. These tools, which typically focus on studying cell behavior and dynamic cell populations, range from systems of differential equations that are solved numerically….

OncologyGut & microbiome

Medium relevance

Shiitake · 2024 · Research Article · Food chemistry: X

Formulation of functional noodles by adding Lentinus edodes mushroom powder: Physiochemical attributes, cellular mineral uptake and improved glycemic index.

This study investigated the physicochemical, low glycemic index, and mineral uptake of functional noodles added with varying concentrations (0-10 %) of Lentinus edodes (also known as shiitake) powder. Noodles with 4 % mushroom powder (L3) exhibited comparable sensory attributes in comparison with control noodles..

Metabolic health

Medium relevance

Reishi · 2024 · Journal Article · Scientific reports

Ganoderma tsuage promotes pain sensitivity in aging mice.

Advances in modern medicine have extended human life expectancy, leading to a world with a gradually aging society. Aging refers to a natural decline in the physiological functions of a species over time, such as reduced pain sensitivity and reaction speed..

OncologyImmune supportMetabolic healthLiver support

Medium relevance

Cordyceps · 2024 · Journal Article · Journal of the Chinese Medical Association: JCMA

Hirsutella sinensis intensifies testicular function and spermatogenesis in male mice with high-fat diet-induced obesity.

BACKGROUND: Hirsutella sinensis (HS) is a mycelium isolated from the fruiting body of the medicinal mushroom Cordyceps sinensis. This study explored whether HS treatment affects reproductive dysfunction in a high-fat diet (HFD)-induced mouse model and regulates various mechanisms, focusing on oxidative stress,….

OncologyImmune supportMetabolic healthLiver support

Medium relevance

Cordyceps · 2024 · Journal Article · Mycoscience

Identification of the oosporein biosynthesis gene cluster in an entomopathogenic fungus Blackwellomyces cardinalis

Blackwellomyces cardinalis (≡ Cordyceps cardinalis) is an entomopathogenic fungus that hosts lepidopteran insect larvae. Oosporein, produced by Bl.

Immune support

Medium relevance

Cordyceps · 2024 · Research Article · Scientific reports

Improved control of Trialeurodes vaporariorum using mixture combinations of entomopathogenic fungi and the chemical insecticide spiromesifen.

Greenhouse whitefly (Trialeurodes vaporariorum) is a major global pest, causing direct damage to plants and transmitting viral plant diseases. Management of T.

Respiratory

Medium relevance

Cordyceps · 2024 · Journal Article · Environmental science and pollution research international

Investigating fungal community characteristics in co-composted cotton stalk and various livestock manure products.

Agricultural wastes, comprising cotton straw and livestock manure, can be effectively managed through aerobic co-composting. Nevertheless, the quality and microbial characteristics of co-composting products from different sources remain unclear..

Cognition & nerves

Medium relevance

Cordyceps · 2024 · Journal Article · Journal of applied microbiology

Isolation and identification of entomopathogenic fungi strains for Colorado potato beetle (Leptinotarsa decemlineata) control.

AIMS: The Colorado potato beetle, Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae) is the most widespread insect pest that causes major economic losses, especially on potatoes. Due to heavy insecticide use, this species now resists most pesticides, posing a significant control challenge..

Medium relevance

Shiitake · 2024 · Journal Article · Cell biochemistry and biophysics

Lentinan mitigates pemetrexed chemoresistance by the PI3K/Akt pathway in non-small cell lung cancer.

Pemetrexed is a folate analog metabolic inhibitor that is given for therapy of non-small cell lung cancer (NSCLC). Drug resistance affects the efficacy of pemetrexed in NSCLC.

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Shiitake · 2024 · Journal Article · International journal of biological macromolecules

Lentinan-loaded GelMA hydrogel accelerates diabetic wound healing through enhanced angiogenesis and immune microenvironment modulation.

Diabetic wound healing is a substantial clinical challenge, characterized by delayed angiogenesis and unresolved inflammation. Lentinan, a polysaccharide extracted from shiitake mushrooms, has the potential to regulate both macrophage polarization and angiogenesis, though this aspect remains inadequately explored..

Immune supportMetabolic healthLiver supportSkin & hydration

Medium relevance

Almond Mushroom · 2024 · Journal Article · Journal of environmental management

Long-term resilience in wastewater management: Optimizing treated wastewater allocation with a dynamic multi-agent approach.

Water scarcity poses a significant challenge to sustainable development, necessitating innovative approaches to manage limited resources efficiently. Effective water resource management involves not just the conservation and distribution of freshwater supplies but also the strategic reuse of treated wastewater (TWW)..

Medium relevance

Almond Mushroom · 2024 · Research Article · Scientific reports

Measuring network dynamics of opioid overdose deaths in the United States.

The US opioid overdose epidemic has been a major public health concern in recent decades. There has been increasing recognition that its etiology is rooted in part in the social contexts that mediate substance use and access; however, reliable statistical measures of social influence are lacking in the literature..

Cognition & nerves

Medium relevance

Almond Mushroom · 2024 · Journal Article · Journal of environmental management

Modeling spatiotemporal domestic wastewater variability: Implications for measuring treatment efficiency.

Continuously measuring the efficiency of wastewater treatment plants is crucial to progress in sanitation management. Regulations for decentralized wastewater treatment plants (WWTP) can include rudimentary specifications for sporadic sampling, unencouraging continuous monitoring, and missing crucial domestic….

Energy & fatigue

Medium relevance

Cordyceps · 2024 · Research Article · Scientific reports

Multi-omics analysis of soil microbiota and metabolites in dryland wheat fields under different tillage methods.

No-tillage and subsoiling can improve soil aggregate structure and realize a synergistic effect of soil carbon and nitrogen retention compared with deep tillage. This study aimed to investigate the effects of different tillage methods on the microbiome and metabolites in wheat rhizosphere..

Gut & microbiome

Medium relevance

Cordyceps · 2024 · Journal Article · Microorganisms

Mycophagous Mite, Tyrophagus putrescentiae, Prefers to Feed on Entomopathogenic Fungi, except Metarhizium Generalists.

(1) Background: The mycophagous mite, Tyrophagus putrescentiae, was found to feed on entomopathogenic fungi (EPF) in our previous experiments, which seriously impacted the culture and preservation of fungal strains..

Gut & microbiome

Medium relevance

Cordyceps · 2024 · Journal Article · RSC advances

Naphthoquinone derivatives as potential immunomodulators: prospective for COVID-19 treatment.

Inflammation plays a crucial role in COVID-19, and when it becomes dysregulated, it can lead to severe outcomes, including death. Naphthoquinones, a class of cyclic organic compounds widely distributed in nature, have attracted significant interest due to their potential biological benefits..

Immune supportRespiratory

Medium relevance

Shiitake · 2024 · Research Article · Frontiers in chemistry

Nitrogen-doped mesoporous activated carbon from Lentinus edodes residue: an optimized adsorbent for pharmaceuticals in aqueous solutions.

In this study, phosphoric acid activation was employed to synthesize nitrogen-doped mesoporous activated carbon (designated as MR1) from Lentinus edodes (shiitake mushroom) residue, while aiming to efficiently remove acetaminophen (APAP), carbamazepine (CBZ), and metronidazole (MNZ) from aqueous solutions..

Medium relevance

King Oyster · 2024 · Journal Article · Zootaxa

On the taxonomy of some South American and Australo-Pacific Anthicidae Latreille, 1819 (Coleoptera) with new subfamily and tribe-rank synonymies.

A monotypic South American genus Micreurygenius Pic, 1942 (hitherto in Eurygeniinae LeConte, 1862) is synonymized with Ischyropalpus La Ferté-Sénectère, 1849 (Anthicini Latreille, 1819) and, accordingly, moved to Anthicinae Latreille, 1819..

Medium relevance

Almond Mushroom · 2024 · Journal Article · European journal of nuclear medicine and molecular imaging

Optimizing the pharmacokinetics of an 211At-labeled RGD peptide with an albumin-binding moiety via the administration of an albumin-binding inhibitor.

PURPOSE: A probe for targeted alpha therapy (TAT) using the RGD peptide (Ga-DOTA-K([211At]APBA)-c(RGDfK) ([211At]1)) with albumin-binding moiety (ABM) was recently developed. [211At]1 highly accumulated in tumors and significantly inhibited tumor growth in U-87 MG tumor-bearing mice..

Oncology

Medium relevance

Cordyceps · 2024 · Journal Article · Biocontrol Science and Technology

Persistence of three biopesticides containing entomopathogenic fungi under tree canopy conditions in Florida, USA

Fungal propagule persistence on avocado bolts (small logs) under fruit tree canopies in Florida, USA was assessed for three entomopathogenic fungus-based biopesticides containing Cordyceps javanica, Metarhizium brunneum, or Beauveria bassiana..

Gut & microbiome

Medium relevance

Almond Mushroom · 2024 · Journal Article · Journal of environmental quality

Pig manure degradation and carbon emission: Measuring and modeling combined aerobic-anaerobic transformations.

Greenhouse gas emissions from liquid livestock manure storage significantly contribute to global warming. Accurate farm-scale models are essential for predicting these emissions and evaluating manure management strategies, but they rely on multiple parameters describing carbon loss dynamics..

Energy & fatigueGut & microbiome

Medium relevance

Oyster Mushroom · 2024 · Journal Article · Environmental pollution (Barking, Essex: 1987)

Porous red mud ceramsite for aquatic phosphorus removal: Application in constructed wetlands.

Red mud (RM) and spent oyster mushroom substrate (SOMS), by-products of industrial and agricultural production, can be recycled for polluted freshwater purification, bringing about a win-win situation..

Energy & fatigue

Medium relevance

Cordyceps · 2024 · Journal Article · Environmental microbiology reports

Pyricularia oryzae enhances Streptomyces griseus growth via non-volatile alkaline metabolites.

Chemical compounds that affect microbial interactions have attracted wide interest. In this study, Streptomyces griseus showed enhanced growth when cocultured with the rice blast fungus Pyricularia oryzae on potato dextrose agar (PDA) medium.

Medium relevance

Cordyceps · 2024 · Journal Article · Journal of economic entomology

Residual effect of commonly used insecticides on key predatory mites released for biocontrol in strawberry.

Florida is the second largest producer of strawberries in the United States. However, the production system faces numerous challenges, especially Scirtothrips dorsalis Hood (Thysanoptera: Thripidae) infestations..

Medium relevance

Shiitake · 2024 · Research Article · Plants (Basel, Switzerland)

Responses of Crop Yield, Soil Fertility, and Heavy Metals to Spent Mushroom Residues Application.

Waste mushroom residues are often returned to fields as organic amendments. Here, we estimated the effects of the continuous applications of different spent mushroom substrates for 2 years on crop yields, soil nutrients, and heavy metals in paddy fields..

Medium relevance

Chaga · 2024 · Research Article · Open forum infectious diseases

Risk Factors for Spotted Fever Group Rickettsioses in Kilimanjaro Region, Tanzania.

BACKGROUND: Knowledge gaps exist on risk factors for spotted fever group rickettsioses (SFGR) in sub-Saharan Africa. We sought to identify SFGR risk factors in Kilimanjaro Region, Tanzania.

Immune support

Medium relevance

Almond Mushroom · 2024 · Journal Article · The Lancet regional health. Southeast Asia

Routine immunization against Streptococcus pneumoniae and Haemophilus influenzae type B and antibiotic consumption in India: a dynamic modeling analysis.

BACKGROUND: Childhood vaccinations can reduce disease burden and associated antibiotic use, in turn reducing the risk of antimicrobial resistance (AMR). We retrospectively estimated the population-level reductions in antibiotic use in India following the introduction of vaccines against Streptococcus pneumoniae and….

Immune supportRespiratory

Medium relevance

Oyster Mushroom · 2024 · Journal Article · International journal of medicinal mushrooms

Size Matters: Influence of Particle Size on Antioxidant, β-Glucan, and Anti-Inflammatory Potential in Pleurotus floridanus (Agaricomycetes).

Cellular damage resulting from elevated levels of free radicals can lead to persistent health issues. Pleurotus floridanus, an edible white oyster mushroom, is rich in β-glucans with potent antioxidant and anti-inflammatory properties..

OncologyImmune support

Medium relevance

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Structural clarification of mannoglucan GSBP-2 from Ganoderma sinense and its effects on triple-negative breast cancer migration and invasion.

Ganoderma sinense, known as Lingzhi in China, is a medicinal fungus with anti-tumor properties. Herein, crude polysaccharides (GSB) extracted from G.

OncologyImmune supportGut & microbiomeSkin & hydration

Medium relevance

Almond Mushroom · 2024 · Journal Article · ArXiv

Surrogate modeling and control of medical digital twins.

The vision of personalized medicine is to identify interventions that maintain or restore a person's health based on their individual biology. Medical digital twins, computational models that integrate a wide range of health-related data about a person and can be dynamically updated, are a key technology that can help….