MycoData

Immune supportEnergy & fatigue

Cordyceps · 2018 · Research Article · 3 Biotech

Proteomic identification of marker proteins and its application to authenticate Ophiocordyceps sinensis.

Ophiocordyceps sinensis (O. sinensis) is a highly valuable fungus because of its nutritious and medicinal properties.

Energy & fatigueGut & microbiome

Enoki · 2026 · Published Erratum · Frontiers in microbiology

Correction: Effects of Flammulina velutipes mushroom residues on growth performance, apparent digestibility, serum biochemical indicators, rumen fermentation and microbial of Guizhou black goat.

[This corrects the article DOI: 10.3389/fmicb.2024.1347853.]..

Almond Mushroom · 2024 · Letter · Asian journal of surgery

Agaricus blazei extract FA-2-b-β inhibits rat C6 glioma cell proliferation by the mitochondrial dysfunction-induced ferroptosis pathway.

Metadata-grounded summary: This letter indexes research on Agaricus blazei in Asian journal of surgery in 2024. MycoData maps the paper to energy & fatigue based on its title, species context, article metadata, and study classification..

Almond Mushroom · 2024 · Letter · Asian journal of surgery

Agaricus blazei Murill extract FA-2-b-β inhibits gastric cancer cell proliferation through the mechanisms of cell-cycle blocking and apoptosis by the mitochondrial pathway.

Metadata-grounded summary: This letter indexes research on Agaricus blazei in Asian journal of surgery in 2024. MycoData maps the paper to oncology, energy & fatigue based on its title, species context, article metadata, and study classification..

Almond Mushroom · 2024 · Letter · Asian journal of surgery

Correlation of the apoptosis in the mitochondrial pathway with the JAK2/STAT3 signaling pathway regarding the effect of Agaricus blazei Murill extract FA-2-b-β in inhibiting the proliferation of gastric cancer cells.

OncologyImmune supportEnergy & fatigueMetabolic health

Reishi · 2023 · Journal Article · International journal of biological macromolecules

A Ganoderma lucidum polysaccharide F31 alleviates hyperglycemia through kidney protection and adipocyte apoptosis.

In this paper, we reported an excellent hypoglycemic effect of a Ganoderma lucidium polysaccharide F31 with efficacies between 45 and 54 %, approaching to that of liraglutide (52 %). Significantly, F31 reduced the body weight gains and food intakes..

Immune supportEnergy & fatigueGut & microbiome

Reishi · 2023 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Fermentation of Ganoderma lucidum and Raphani Semen with a probiotic mixture attenuates cyclophosphamide-induced immunosuppression through microbiota-dependent or -independent regulation of intestinal mucosal barrier and immune responses.

BACKGROUND: Probiotic fermentation is a promising strategy for improving the nutritional and functional properties of traditional Chinese medicines (TCMs). Ganoderma lucidum and Raphani Semen are famous TCMs that have been shown to help alleviate immune system disorders..

OncologyImmune supportEnergy & fatigueGut & microbiome

Maitake · 2023 · Preprint · journal metadata

Influence of Dried Maitake and Enoki Mushroom Addition on Antioxidant, Potentially Anti-inflammatory, and Anti-cancer Properties of Enriched Pasta

The influence of the addition of 2.5, 5, 7.5, and 10.0% of dried Enoki and Maitake mushrooms on the content of bioactive compounds and some pro-health properties of pasta was studied..

Immune supportEnergy & fatigue

Oyster Mushroom · 2023 · Research Article · Foods (Basel, Switzerland)

Optimization of Plasma Activated Water Extraction of Pleurotus ostreatus Polysaccharides on Its Physiochemical and Biological Activity Using Response Surface Methodology.

This study focused on optimizing the extraction of P. ostreatus polysaccharides (POPs) using plasma-activated water (PAW).

Turkey Tail · 2023 · Research Article · International journal of molecular sciences

Studies on the Oxidation of Aromatic Amines Catalyzed by Trametes versicolor Laccase.

The bio-oxidation of a series of aromatic amines catalyzed by T. versicolor laccase has been investigated exploiting either commercially available nitrogenous substrates [(E)-4-vinyl aniline and diphenyl amine] or ad hoc synthetized ones [(E)-4-styrylaniline, (E)-4-(prop-1-en-1-yl)aniline and….

Energy & fatigueMetabolic health

Almond Mushroom · 2023 · Preprint · journal metadata

The role of LRP5-LRP6 gene-gene and gene-environment interactions on the risk of ABM in postmenopausal women with type 2 diabetes mellitus

Background: A previous work has discovered that LRP5 and LRP6 locus are linked to the risk of ABM in postmenopausal women with type 2 diabetes mellitus (T2DM). This study aimed to investigate the role of LRP5-LRP6 SNP and gene-gene and gene-environment interactions in the development of ABM in postmenopausal women….

Energy & fatigueMetabolic health

Shiitake · 2023 · Research Article · Food chemistry. Molecular sciences

Transcriptome analysis provides insight into gamma irradiation delaying quality deterioration of postharvest Lentinula edodes during cold storage.

To better determine how gamma irradiation (GI) improves abiotic stress resistance, a transcriptome analysis of postharvest L. edodes in response to 1.0 kGy GI was conducted, and further the underlying mechanism of GI in delaying quality deterioration over 20 d of cold storage was explored..

Energy & fatigueGut & microbiome

Shiitake · 2022 · Research Article · Animals: an open access journal from MDPI

Effect of Two Feed Additives-One Multicomponent Based on Nanosilica and the Second Containing Mycelium of Lentinula edodes Fortified with Selenium-On Production Parameters and Histological Analysis of Calves' Duodenum and Abdominal Rumen.

With this study, we aimed to evaluate the effect of two multicomponent feed additives given to animals from 10 to 70 d with milk replacer on the production parameters of reared calves: serum selenium level and histology of duodenum and rumen..

OncologyImmune supportEnergy & fatigueRespiratory

Shiitake · 2022 · Research Article · Infection and drug resistance

In vitro Anti SARS-CoV-2 Activity and Docking Analysis of Pleurotus ostreatus, Lentinula edodes and Agaricus bisporus Edible Mushrooms.

BACKGROUND: Fungi are rich source of biologically active metabolites aimed for the improvement of human health through the prevention of various diseases, including infections and inflammatory disorders..

Turkey Tail · 2022 · Journal Article · Environmental science and pollution research international

Kinetics and mechanisms for sulfamethoxazole transformation in the phenolic acid-laccase (Trametes versicolor) system.

Oxidation of phenolic acids (PCs) by laccase could produce various kinds of reactive oxygen species (ROS), which is expected to have substantial impact on the transformation of antibiotics like sulfamethoxazole (SMX) in soil and aquatic environments..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2021 · Journal Article · British poultry science

Agaricus subrufescens and Pleurotus ostreatus mushrooms as alternative additives to antibiotics in diets for broilers challenged with Eimeria spp.

1. The effect of A.

Shiitake · 2021 · Journal Article · Journal of agricultural and food chemistry

Biosynthetic Mechanism of Key Volatile Biomarkers of Harvested Lentinula edodes Triggered by Spore Release.

In this study, headspace solid-phase microextraction-gas chromatography-mass spectrometry, multivariate analyses, and transcriptomics were used to explore the biosynthesis of key volatiles and the formation of spores in Lentinula (L.) edodes..

Cordyceps · 2021 · Preprint · journal metadata

Comparative analysis of the complete mitochondrial genomes of four cordyceps fungi

Cordyceps is a large group of entomogenous, medicinally important fungi. In this study, we sequenced, assembled, and annotated the entire mitochondrial genome of O.

Immune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2021 · Research Article · International journal of molecular sciences

Neuroprotective Metabolites of Hericium erinaceus Promote Neuro-Healthy Aging.

Frailty is a geriatric syndrome associated with both locomotor and cognitive decline, typically linked to chronic systemic inflammation, i.e., inflammaging. In the current study, we investigated the effect of a two-month oral supplementation with standardized extracts of H..

Energy & fatigueGut & microbiome

Shiitake · 2021 · Preprint · journal metadata

Shiitake mycelium fermentation improves digestibility, nutritional value, flavor and functionality of plant proteins

ABSTRACT Plant proteins can serve as inexpensive and environmentally friendly meat-replacements. However, poor taste characteristics and relatively low nutritional value prevent their full acceptance as meat substitutes.

King Oyster · 2021 · Research Support, Non U.S. Gov'T · Biodegradation

The optimization of enzymatic oxidation of levofloxacin, a fluoroquinolone antibiotic for wastetwater treatment.

The global presence of antibiotics in the environment has created concerns about the emergence of antibiotic resistance bacteria and potential hazard to humans and the ecosystem..

Turkey Tail · 2020 · Comparative Study · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Acetylsalicylic acid-like analgesic effects of Trametes versicolor in Wistar rats.

The aim of the present study was to investigate the analgesic effects and mechanism of action of Trametes versicolor (Tv) mycelium powder. Wistar rats were randomly divided into the following three or four groups: i) Saline group, fed saline; ii) Tv 500 group, fed 500 mg/kg Tv; iii) ASA 50 group, fed 50 mg/kg….

OncologyImmune supportCognition & nervesEnergy & fatigue

Niu-Chang-Chih · 2020 · Research Support, Non U.S. Gov'T · Brain and behavior

Antrodia camphorata polysaccharide resists 6-OHDA-induced dopaminergic neuronal damage by inhibiting ROS-NLRP3 activation.

INTRODUCTION: Parkinson's disease (PD) is a common degenerative disease of the central nervous system (CNS). The main pathological change is the apoptosis of dopaminergic neurons in the substantia nigra pars compacta (SNPc), thereby leading to dopamine reduction in nigral striatum..

Snow Fungus · 2020 · Comparative Study · BMC genomics

Intra-specific comparison of mitochondrial genomes reveals host gene fragment exchange via intron mobility in Tremella fuciformis.

BACKGROUND: Mitochondrial genomic sequences are known to be variable. Comparative analyses of mitochondrial genomes can reveal the nature and extent of their variation.

Energy & fatigueMetabolic healthGut & microbiome

Shiitake · 2020 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Structure characterization of soluble dietary fiber fractions from mushroom Lentinula edodes (Berk.) Pegler and the effects on fermentation and human gut microbiota in vitro.

Aimed to evaluate the changes of three soluble dietary fibers from Lentinula edodes by-products (LESDF) with different molecular weights in the digestive system and their effects on large intestinal fermentation, fermentation products and the types of gut microbiota were determined..

OncologyImmune supportEnergy & fatigueMetabolic health

Maitake · 2020 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy.

Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G.

Turkey Tail · 2020 · Comparative Study · Bioprocess and biosystems engineering

Trametes versicolor laccase production using agricultural wastes: a comparative study in Erlenmeyer flasks, bioreactor and tray.

Laccases are very interesting biocatalysts of recognized importance for several industrial applications. Its production by Trametes versicolor, a white-rot fungus, was induced by a combination of cotton gin wastes (1%), a lignocellulosic waste, and vinasse (15%), an industrial by-product from sugarcane industry..

Shiitake · 2020 · Research Support, Non U.S. Gov'T · PloS one

Transcriptome analysis of the edible mushroom Lentinula edodes in response to blue light.

Lentinula edodes is one of the most popular edible mushrooms worldwide and contains important medicinal components such as lentinan, ergosterol, and eritadenine. Mushroom metabolism is regulated by the mycelia and fruit body using light; however, in mushrooms, the underlying molecular mechanisms controlling this….

Almond Mushroom · 2019 · Comparative Study · Food research international (Ottawa, Ont.)

A comparative study between conventional and non-conventional extraction techniques for the recovery of ergosterol from Agaricus blazei Murrill.

Response surface methodology was applied to optimize the recovery of ergosterol from an agroindustrial residue of Agaricus blazei Murrill, by comparing conventional (heat-assisted extraction, HAE) and more sustainable non-conventional approaches (ultrasound and microwave-assisted extractions, UAE and MAE,….

Shiitake · 2019 · Research Support, Non U.S. Gov'T · Scientific reports

Mitogenome types of two Lentinula edodes sensu lato populations in China.

China has two populations of Lentinula edodes sensu lato as follows: L. edodes sensu stricto and an unexcavated morphological species respectively designated as A and B..

Cordyceps · 2019 · Research Support, Non U.S. Gov'T · Zoology (Jena, Germany)

Phylogeographic structures of the host insects of Ophiocordyceps sinensis.

A fungus-insect complex, known as DongChong XiaCao, is formed from the infection of the hepialid larvae by the fungus Ophiocordyceps sinensis, which is endemic to the Qinghai-Tibetan Plateau (QTP)..

Shiitake · 2019 · Research Support, Non U.S. Gov'T · Genes

Variable Number Tandem Repeats in the Mitochondrial DNA of Lentinula edodes.

Variable number tandem repeats (VNTRs) in mitochondrial DNA (mtDNA) of Lentinula edodes are of interest for their role in mtDNA variation and their application as genetic marker. Sequence analysis of three L.

Energy & fatigueMetabolic health

Enoki · 2018 · Comparative Study · Journal of agricultural and food chemistry

A Comparative Proteome Approach Reveals Metabolic Changes Associated with Flammulina velutipes Mycelia in Response to Cold and Light Stress.

In some industrial processes, cold and light stresses are recognized as two important environmental triggers for the transformation of mycelia into fruit-bodies via intermediate primordia in Flammulina velutipes cultivation. To gain insights into the mechanism of regulation of F..

Shiitake · 2018 · Comparative Study · Scientific reports

Comparative transcriptome analysis of dikaryotic mycelia and mature fruiting bodies in the edible mushroom Lentinula edodes.

Lentinula edodes is a popular cultivated edible mushroom with high nutritional and medicinal value. To understand the regulation of gene expression in the dikaryotic mycelium and mature fruiting body in the commercially important Korean L..

Almond Mushroom · 2018 · Research Support, Non U.S. Gov'T · Biotechnology progress

High-performance of Agaricus blazei fungus for the biological pretreatment of elephant grass.

Biological pre-treatment seems to be promising being an eco-friendly process, with no inhibitor generated during the process. The potential for elephant grass pre-treatment with white degradation fungi Pleurotus ostreatus, Agaricus blazei, Lentinula edodes, Pleurotus citrinopileatus, and Pleurotus djamor, in isolated….

OncologyImmune supportEnergy & fatigueGut & microbiome

Lion's Mane · 2018 · Research Support, Non U.S. Gov'T · The Journal of nutritional biochemistry

Polysaccharide of Hericium erinaceus attenuates colitis in C57BL/6 mice via regulation of oxidative stress, inflammation-related signaling pathways and modulating the composition of the gut microbiota.

Inflammatory bowel disease (IBD) is a disease caused by a dysregulated immune with unknown etiology. Hericium erinaceus (H.

Immune supportEnergy & fatigueMetabolic health

Turkey Tail · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Proteomic analysis reveals large amounts of decomposition enzymes and major metabolic pathways involved in algicidal process of Trametes versicolor F21a.

A recent algicidal mode indicates that fungal mycelia can wrap and eliminate almost all co-cultivated algal cells within a short time span. However, the underlying molecular mechanism is rarely understood..

OncologyImmune supportEnergy & fatigue

Niu-Chang-Chih · 2016 · Research Support, Non U.S. Gov'T · International immunopharmacology

4,7-Dimethoxy-5-methyl-1,3-benzodioxole from Antrodia camphorata inhibits LPS-induced inflammation via suppression of NF-κB and induction HO-1 in RAW264.7 cells.

Several benzenoid compounds have been isolated from Antrodia camphorata are known to have excellent anti-inflammatory activity. In this study, we investigated the anti-inflammatory potential of 4,7-dimethoxy-5-methyl-1,3-benzodioxole (DMB), one of the major benzenoid compounds isolated from the mycelia of A..

Immune supportEnergy & fatigueGut & microbiome

Almond Mushroom · 2016 · Research Support, Non U.S. Gov'T · PloS one

Effect of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan™, on Symptoms, Fatigue and Quality of Life in Patients with Ulcerative Colitis in a Randomized Single-Blinded Placebo Controlled Study.

BACKGROUND: Ingestion of AndoSan™, based on the mushroom Agaricus blazei Murill, has previously been shown to exhibit anti-inflammatory effects because of reduction of pro-inflammatory cytokines in healthy individuals and patients with ulcerative colitis..

Maitake · 2016 · Research Support, Non U.S. Gov'T · Nutrition and cancer

Grifola frondosa Glycoprotein GFG-3a Arrests S phase, Alters Proteome, and Induces Apoptosis in Human Gastric Cancer Cells.

GFG-3a is a novel glycoprotein previously purified from the fermented mycelia of Grifola frondosa with novel sugar compositions and protein sequencing. The present study aims to investigate its effects on the cell cycle, differential proteins expression, and apoptosis of human gastric cancer SGC-7901 cells..

OncologyImmune supportEnergy & fatigue

Lion's Mane · 2016 · Research Support, Non U.S. Gov'T · Oxidative medicine and cellular longevity

Hericium erinaceus Inhibits TNF-α-Induced Angiogenesis and ROS Generation through Suppression of MMP-9/NF-κB Signaling and Activation of Nrf2-Mediated Antioxidant Genes in Human EA.hy926 Endothelial Cells.

Hericium erinaceus (HE) is an edible mushroom that has been shown to exhibit anticancer and anti-inflammatory activities. We investigated the antiangiogenic and antioxidant potentials of ethanol extracts of HE in human endothelial (EA.hy926) cells upon tumor necrosis factor-α- (TNF-α-) stimulation (10 ng/mL)..

OncologyCognition & nervesEnergy & fatigue

Enoki · 2016 · Research Support, Non U.S. Gov'T · Food chemistry

Identification of flavonoids from Flammulina velutipes and its neuroprotective effect on pheochromocytoma-12 cells.

The flavonoids from Flammulina velutipes (FVF) were isolated and the chemical composition of FVF was identified by high-performance liquid chromatography/mass spectrometry (HPLC/MS)..

Zhu Ling · 2016 · Research Support, Non U.S. Gov'T · Molecular medicine reports

Induction of apoptosis in MCF‑7 human breast cancer cells by Khz (fusion of Ganoderma lucidum and Polyporus umbellatus mycelium).

Khz (fusion of Ganoderma lucidum and Polyporus umbellatus), isolated from the mycelia of G. lucidum and P.

OncologyCognition & nervesEnergy & fatigue

Mesima · 2016 · Research Support, Non U.S. Gov'T · Nutrition research (New York, N.Y.)

Neuroprotective effects of the Phellinus linteus ethyl acetate extract against H2O2-induced apoptotic cell death of SK-N-MC cells.

Numerous studies have suggested that neuronal cells are protected against oxidative stress-induced cell damage by antioxidants, such as polyphenolic compounds. Phellinus linteus (PL) has traditionally been used to treat various symptoms in East Asian countries..

Shiitake · 2016 · Brief Report · Mycobiology

Oxalic Acid from Lentinula edodes Culture Filtrate: Antimicrobial Activity on Phytopathogenic Bacteria and Qualitative and Quantitative Analyses.

The culture filtrate of Lentinula edodes shows potent antimicrobial activity against the plant pathogenic bacteria Ralstonia solanacearum. Bioassay-guided fractionation was conducted using Diaion HP-20 column chromatography, and the insoluble active compound was not adsorbed on the resin..

Immune supportEnergy & fatigue

Lion's Mane · 2015 · Research Article · Experimental and therapeutic medicine

Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus.

Hericium erinaceus (HEP) is a notable medicinal fungus grown in China and other oriental countries. Polysaccharides from HEP have recently attracted considerable attention due to their numerous physiological activities.

OncologyCognition & nervesEnergy & fatigueLiver support

Niu-Chang-Chih · 2015 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Antrodia camphorata Potentiates Neuroprotection against Cerebral Ischemia in Rats via Downregulation of iNOS/HO-1/Bax and Activated Caspase-3 and Inhibition of Hydroxyl Radical Formation.

Antrodia camphorata (A. camphorata) is a fungus generally used in Chinese folk medicine for treatment of viral hepatitis and cancer.

Mesima · 2015 · Research Article · Mycobiology

Chemical Constituents of the Culture Broth of Phellinus linteus and Their Antioxidant Activity.

The medicinal fungus Phellinus linteus, in the family Hymenochaetaceae, has been used as a traditional medicine for the treatment of various diseases. In this study, the chemical constituents of the culture broth of P.

Shiitake · 2015 · Journal Article · Brazilian journal of biology = Revista brasleira de biologia

Influence of nitrogen sources on the enzymatic activity and grown by Lentinula edodes in biomass Eucalyptus benthamii.

Lignocellulose is the most abundant environmental component and a renewable organic resource in soil. There are some filamentous fungi which developed the ability to break down and use cellulose, hemicellulose and lignin as an energy source..