MycoData

Shiitake mushroom cultivation could effectively reduce the recalcitrance of hardwood, facilitating cellulosic ethanol production. However, the shiitake pretreated spent mushroom substrates (SMS) have exhibited significant variations in enzymatic saccharification and fermentation efficiencies in previous studies..

Gut & microbiome

Medium relevance

Almond Mushroom · 2025 · Research Article · mSystems

MetaBiome: a multiscale model integrating agent-based and metabolic networks to reveal spatial regulation in gut mucosal microbial communities.

Mucosal microbial communities (MMCs) are complex ecosystems near the mucosal layers of the gut essential for maintaining health and modulating disease states. Despite advances in high-throughput omics technologies, current methodologies struggle to capture the dynamic metabolic interactions and spatiotemporal….

Energy & fatigueMetabolic healthGut & microbiome

Medium relevance

Almond Mushroom · 2025 · Journal Article · Environmental science and pollution research international

Sublethal pesticide exposure alters stress response, detoxification, and immunity gene expression in larvae of the stingless bee Frieseomelitta varia (Apidae: Meliponini).

During foraging, stingless bees are at risk of pesticide contamination from treated field crops. Frieseomellita varia workers, for example, frequently visit pepper plants that are often treated with the herbicide clomazone (CLZ), the fungicide difenoconazole (DFZ), and the insecticide abamectin (ABM)..

Immune supportGut & microbiome

Medium relevance

Almond Mushroom · 2025 · Journal Article · Archives of microbiology

Yeast's vacuole a privileged niche that protects intracellular bacteria against antibiotics.

Detection of Helicobacter pylori, Staphylococcus, Nocardia and Cyanobacteria inside the yeast Candida tropicalis raised the question whether treating yeast with antibiotics mix (ABM) eliminates intracellular bacteria. Live/Dead staining showed occurrence of viable bacteria inside the vacuole of C.

Metabolic healthGut & microbiome

Medium relevance

Almond Mushroom · 2024 · Research Article · NPJ biofilms and microbiomes

Metabolic interactions shape emergent biofilm structures in a conceptual model of gut mucosal bacterial communities.

The gut microbiome plays a major role in human health; however, little is known about the structural arrangement of microbes and factors governing their distribution. In this work, we present an in silico agent-based model (ABM) to conceptually simulate the dynamics of gut mucosal bacterial communities..

Metabolic healthGut & microbiome

Medium relevance

Agarikon · 2024 · Research Article · Frontiers in pharmacology

Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways.

INTRODUCTION: Colorectal cancer ranks as the third most common cancer in both men and women, with approximately 35% of cases being stage IV metastatic at diagnosis. Even with treatment advancements, the survival rates for these patients remain suboptimal..

OncologyImmune supportMetabolic healthGut & microbiome

Medium relevance

Shiitake · 2024 · Research Article · Foods (Basel, Switzerland)

Screening Traditional Foods for the Prevention of Enterotoxigenic Escherichia coli K88ac (F4ac) Attachment to IPEC-J2 Cells.

Enterotoxigenic Escherichia coli (ETEC) is the major diarrhoea-causing pathogen world-wide. Fimbria-receptor recognition is the primary step when attachment of ETEC to the intestine occurs..

Cognition & nervesGut & microbiome

Medium relevance

King Oyster · 2020 · Journal Article · Animal: an international journal of animal bioscience

A diet containing native or fermented wheat bran does not interfere with natural microbiota of laying hens.

Wheat bran (WB) is an important side product of the milling industry and can serve as dietary fiber compound for monogastric animals. The aim of this study was to evaluate the influence of native or fermented WB on the gut physiology and microbiology of laying hens..

Energy & fatigueGut & microbiome

Medium relevance

King Oyster · 2020 · Journal Article · Bioresource technology

High-potency white-rot fungal strains and duration of fermentation to optimize corn straw as ruminant feed.

Five white-rot fungi Pleurotus ostreatus, Lentinus edodes, Hericium erinaceus, Pleurotus eryngii and Flammulina filiformis were studied (solid-state incubation and in vitro gas production) to determine lignin degradation and optimal duration of fermentation of corn straw..

Gut & microbiome

Medium relevance

Maitake · 2010 · Research Support, Non U.S. Gov'T · Cancer immunology, immunotherapy: CII

Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity.

Bone marrow myelotoxicity is a major limitation of chemotherapy. While granulocyte colony stimulating factor (G-CSF) treatment is effective, alternative approaches to support hematopoietic recovery are sought..

OncologyImmune supportEnergy & fatigueGut & microbiome

Medium relevance

Maitake · 2007 · Research Support, Non U.S. Gov'T · Clinical and vaccine immunology: CVI

Enhancement of umbilical cord blood cell hematopoiesis by maitake beta-glucan is mediated by granulocyte colony-stimulating factor production.

Maitake beta-glucan (MBG) is an extract from the fruit body of the Grifola frondosa mushroom that is being widely used to treat cancer in Asia. We have previously reported that MBG enhances mouse bone marrow cell (BMC) hematopoiesis in vitro and protects BMC from doxorubicin (DOX) toxicity..

OncologyImmune supportGut & microbiome

Medium relevance

Cordyceps · 2025 · Research Support, Non U.S. Gov'T · Molecular nutrition & food research

Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional Implications.

This systematic review examines the antidepressant potential of edible medicinal fungi (EMFs), focusing on their bioactive compounds and mechanisms of action. EMFs modulate neurotransmitter systems, including serotonin (5-HT) and dopamine (DA), alleviating depressive symptoms..

Immune supportCognition & nervesGut & microbiome

Medium relevance

King Oyster · 2025 · Evaluation Study · Food chemistry

Successive fungal solid-state fermentation and UV-B irradiation: A novel strategy to boost bioactive potential and vitamin D2 levels of corn flour.

This study introduces a novel biofortification strategy that combines solid-state fermentation (SSF) using edible fungi Pleurotus eryngii and Hericium erinaceus, followed by UV-B irradiation of colonized corn flour, to enhance its vitamin D₂ content and functional properties..

Gut & microbiome

Medium relevance

King Oyster · 2024 · Research Support, Non U.S. Gov'T · Journal of hazardous materials

Bioremediation of petroleum hydrocarbons polluted soil by spent mushroom substrates: Microbiological structure and functionality.

Spent mushroom substrate (SMS) holds valuable microbiota that can be useful in remediating polluted soils with hydrocarbons. However, the microorganisms behind the bioremediation process remain uncertain..

Gut & microbiome

Medium relevance

King Oyster · 2023 · Journal Article · Preparative biochemistry & biotechnology

Agro-industrial wastes revalorization as feedstock: production of lignin-modifying enzymes extracts by solid-state fermentation using white rot fungi.

The purpose of the study was to evaluate the production of lignin-modifying enzyme extracts and delignified biomass from agro-industrial wastes using white rot fungi (Inonotus sp. Sp2, Stereum hirsutum Ru-104, Bjerkandera sp.

Gut & microbiome

Medium relevance

King Oyster · 2023 · Research Article · ACS omega

Cellulose Fiber Rejects as Raw Material for Integrated Production of Pleurotus spp. Mushrooms and Activated Biochar for Removal of Emerging Pollutants from Aqueous Media.

Cellulose fiber rejects from industrial-scale recycling of waste papers were dried and de-ashed using a combined cyclone-drying and sieving process. The upgraded fiber reject was used as a component of substrates for the cultivation of Pleurotus ostreatus and Pleurotus eryngii mushrooms..

Gut & microbiome

Medium relevance

Cordyceps · 2023 · Research Article · Journal of cancer research and clinical oncology

Cordycepin remodels the tumor microenvironment of colorectal cancer by down-regulating the expression of PD-L1.

PURPOSE: Colorectal cancer, as a common malignant tumor, poses a serious threat to human life. Cordycepin, derived from Cordyceps militaris extract, which was established as a capable inhibitor of tumor growth.

OncologyGut & microbiome

Medium relevance

Lion's Mane · 2023 · Research Article · Molecules (Basel, Switzerland)

Deacylated Derivative of Hericenone C Treated by Lipase Shows Enhanced Neuroprotective Properties Compared to Its Parent Compound.

Hericium erinaceus, a mushroom species commonly known as Yamabushitake in Japan, is known to have a stimulatory effect on neurotrophic factors, such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF)..

Cognition & nervesMetabolic healthGut & microbiome

Medium relevance

King Oyster · 2023 · Research Article · Animals: an open access journal from MDPI

Fermentation Quality, In Vitro Digestibility, and Aerobic Stability of Ensiling Spent Mushroom Substrate with Microbial Additives.

This experiment investigated the effects of lactic acid bacteria and cellulase on the fermentation quality, in vitro digestibility, and aerobic stability of Flammulina velutipes spent mushroom substrate silage (F-silage) and Pleurotus eryngii spent mushroom substrate silage (P-silage)..

Gut & microbiome

Medium relevance

King Oyster · 2023 · Research Article · Molecules (Basel, Switzerland)

Protection and Disinfection Activities of Oregano and Thyme Essential Oils Encapsulated in Poly(ε-caprolactone) Nanocapsules.

The biocolonization of building materials by microorganisms is one of the main causes of their degradation. Fungi and bacteria products can have an undesirable impact on human health.

Gut & microbiome

Medium relevance

King Oyster · 2023 · Research Article · Journal of fungi (Basel, Switzerland)

Solid-State Fermentation with White Rot Fungi (Pleurotus Species) Improves the Chemical Composition of Highland Barley Straw as a Ruminant Feed and Enhances In Vitro Rumen Digestibility.

Lignin degradation is important for enhancing the digestibility and improving the nutritive quality of ruminant feeds. White rot fungi are well known for their bioconversion of lignocellulosic biomass..

Metabolic healthGut & microbiome

Medium relevance

Oyster Mushroom · 2023 · Research Article · Heliyon

Zinc bioaccessibility in finger millet porridge blended with zinc-dense mushroom.

INTRODUCTION: Zinc deficiency is a common health problem among people who rely heavily on cereal-based foods. Consequently, most people from low-income families, particularly young children in Sub-Saharan Africa, who rely mainly on cereal-based meals, have suffered from Zinc deficiency-related health issues..

Cognition & nervesGut & microbiome

Medium relevance

Cordyceps · 2022 · Journal Article · International immunopharmacology

Cordycepin enhances anti-tumor immunity in colon cancer by inhibiting phagocytosis immune checkpoint CD47 expression.

Cordycepin, also known as 3'-deoxyadenosine, is an extract from Cordyceps militaris, which has been reported as an anti-inflammation and anti-tumor substance without toxicity. However, the pharmacological mechanism of Cordycepin on tumor immunity under its anti-tumor effect has not yet been elucidated..

OncologyImmune supportGut & microbiome

Medium relevance

Cordyceps · 2022 · Research Article · Cell journal

Cordycepin Suppresses The Malignant Phenotypes of Colon Cancer Cells through The GSK3ß/ß-catenin/cyclin D1 Signaling Pathway.

OBJECTIVE: Cordycepin, also known as 3'-deoxyadenosine, is the main bioactive ingredient of Cordyceps militaris and possesses various pharmacological effects. This study was performed to investigate the role of cordycepin in regulating the biological behaviors of colon cancer cells and the potential mechanism behind….

OncologyGut & microbiomeSkin & hydrationRespiratory

Medium relevance

Shiitake · 2022 · Journal Article · Journal of food composition and analysis

Facile extraction of nanosized β-glucans from edible mushrooms and their antitumor activities

It has been recently reported that, β-Glucans with globular small particle size confer a higher disease resistance due to its induced strong immunomodulating activity. Herein, this work was designed to directly extract the nano β-glucans (NGs) from mushrooms using an acid-base procedure..

OncologyImmune supportGut & microbiome

Medium relevance

Cordyceps · 2022 · Research Article · Royal Society open science

Language of fungi derived from their electrical spiking activity.

Fungi exhibit oscillations of extracellular electrical potential recorded via differential electrodes inserted into a substrate colonized by mycelium or directly into sporocarps..

Gut & microbiome

Medium relevance

Oyster Mushroom · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Phylogenesis of the Functional 1-Aminocyclopropane-1-Carboxylate Oxidase of Fungi and Plants.

The 1-aminocyclopropane-1-carboxylic acid (ACC) pathway that synthesizes ethylene is shared in seed plants, fungi and probably other organisms. However, the evolutionary relationship of the key enzyme ACC oxidase (ACO) in the pathway among organisms remains unknown..

Gut & microbiome

Medium relevance

King Oyster · 2022 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Physical, chemical, sensorial properties and in vitro digestibility of wheat bread enriched with yunnan commercial and wild edible mushrooms

A high glycaemic index diet would cause a rapid increase in blood sugar levels and lead to chronic metabolic disorders. In this study, wheat bread enriched with mushroom (Pleurotus eryngii and Cantharellus cibarius) powder at different content (0, 5, 10, and 15 g/100 g replacement based on total weight) was prepared..

Metabolic healthGut & microbiome

Medium relevance

Oyster Mushroom · 2021 · Journal Article · Food chemistry

Edible mushrooms dietary fibre and antioxidants: Effects on glycaemic load manipulation and their correlations pre-and post-simulated in vitro digestion.

In this study, mushroom stems were separated from the fruiting body of two edible mushrooms, white button mushroom (WB, Agaricus bisporus) and oyster mushroom (OY, Pleurotus ostreatus), and their functionalities were compared in wheat flour noodles at fortification levels of 5, 10, 15%..

Metabolic healthGut & microbiome

Medium relevance

King Oyster · 2021 · Research Article · Animal bioscience

Effects of mushroom waster medium and stalk residues on the growth performance and oxidative status in broilers.

OBJECTIVE: The study developed mushroom stalk residues as feed additives in the broiler diet for improving the growth performance and immunity of broilers as well as to increase the value of mushroom stalk residues..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Medium relevance

Cordyceps · 2021 · Journal Article · RSC advances

In silico and in vitro design of cordycepin encapsulation in liposomes for colon cancer treatment.

Cordycepin or 3'-deoxyadenosine is an interesting anti-cancer drug candidate that is found in abundance in the fungus Cordyceps militaris. It inhibits cellular growth of many cancers including lung carcinoma, melanoma, bladder cancer, and colon cancer by inducing apoptosis, anti-proliferation, anti-metastasis and by….

OncologyEnergy & fatigueMetabolic healthGut & microbiome

Medium relevance

King Oyster · 2021 · Research Article · Animals: an open access journal from MDPI

Intestinal Microbiota, Anti-Inflammatory, and Anti-Oxidative Status of Broiler Chickens Fed Diets Containing Mushroom Waste Compost By-Products.

This study investigated the effects of using mushroom waste compost as the residue medium for Pleurotus eryngii planting, which was used as a feed replacement; its consequent influence on broiler chickens' intestinal microbiota, anti-inflammatory responses, and anti-oxidative status was likewise studied..

Immune supportGut & microbiomeLiver support

Medium relevance

King Oyster · 2021 · Research Article · Nutrients

The Use of Mushrooms and Spirulina Algae as Supplements to Prevent Growth Inhibition in a Pre-Clinical Model for an Unbalanced Diet.

Today's eating patterns are characterized by the consumption of unbalanced diets (UBDs) resulting in a variety of health consequences on the one hand, and the consumption of dietary supplements in order to achieve overall health and wellness on the other..

Immune supportGut & microbiome

Medium relevance

Reishi · 2005 · Journal Article · The Journal of Japan Mibyou System Association

Decrease of Small Intestinal Damage Caused by 5FU Treated with a Water-soluble Extract from Cultured Medium of Ganoderma lucidum (Rei-shi) mycelia

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in The Journal of Japan Mibyou System Association in 2005. MycoData maps the paper to gut & microbiome based on its title, species context, article metadata, and study classification..

Gut & microbiome

Medium relevance

Shiitake · 2005 · Journal Article · Mushroom Science and Biotechnology

Influence of supplements in sawdust substrates on fruit body tastes of Lentinula edodes

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2005. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2004 · Journal Article · Mycoscience

Biological and inherited characteristics of a newly identified Lentinula edodes strain capable of forming a fruiting body without a shift to low temperature

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mycoscience in 2004. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2004 · Journal Article · Mycoscience

Estimation of viability of inner bark tissue of Quercus serrata, a substrate for log cultivation of Lentinula edodes, using the TTC assay method

Immune supportGut & microbiome

Medium relevance

Shiitake · 2003 · Journal Article · Mushroom science and biotechnology

Effect of Temperature and Moisture Content on Competition between Graphostroma platystoma and Lentinula edodes on Branch Segment in Container

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom science and biotechnology in 2003. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2003 · Journal Article · Mycoscience

Genetic differences in wild strains of Lentinula edodes collected from a single fallen tree

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mycoscience in 2003. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2002 · Journal Article · Mushroom science and biotechnology

Antagonistic Interactions between Trichoderma harzianum and Lentinula edodes

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom science and biotechnology in 2002. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2002 · Journal Article · Mushroom science and biotechnology

Comparison of defatted rice bran with raw rice bran as a supplement for Lentinula edodes sawdust-based cultivation

Immune supportGut & microbiome

Medium relevance

Shiitake · 2002 · Journal Article · Mycoscience

Inﬂuence of contamination by Penicillium brevicompactum and Trichoderma harzianum during Lentinula edodes spawn run on fruiting in sawdust-based substrates

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mycoscience in 2002. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2002 · Journal Article · Mushroom science and biotechnology

Influence of storage of raw and defatted rice brans as supplements for Lentinula edodes sawdust-based substrate on mycelial growth and fruit body production

Immune supportGut & microbiome

Medium relevance

Shiitake · 2001 · Journal Article · Applied Forest Science

Cultivation of Lentinula edodes using Quercus trees killed en masse.

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Applied Forest Science in 2001. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2001 · Journal Article · Mushroom science and biotechnology

Effect of electric impulse on fruit body production of Lentinula edodes in the sawdust-based substrate

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom science and biotechnology in 2001. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2001 · Journal Article · Mushroom science and biotechnology

Production of A and B incompatibility factor recombinants of Lentinula edodes by sexual reproduction

Immune supportGut & microbiome

Medium relevance

Shiitake · 2001 · Journal Article · Mycoscience

Purification and characterization of an extracellular acid trehalase from Lentinula edodes

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mycoscience in 2001. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Yellow Morel · 1999 · Journal Article · Journal of Yanan University (Natural Science Edition)

A findingss report on the resources of Morchella esculenta in Nanniwan of Northearn Shan^anxi

A restriction endonuclease cleavage map is presented for mouse mitochondrial DNA. This map was constructed by electron microscopic measurements on partial digests containing fixed D-loops, and by electrophoretic analysis of partial and complete single enzyme digests, and of double digests..

Energy & fatigueGut & microbiome

Medium relevance

Shiitake · 1999 · Journal Article · Mushroom science and biotechnology

Cultivation of Lentinula edodes using the steamed and hot water-extracted residue of bamboo grass leaves

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom science and biotechnology in 1999. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Medium relevance

Shiitake · 1999 · Journal Article · Mushroom science and biotechnology

Effect of moisture content for mycelial growth and primordial formation of Lentinula edodes in a sawdust-based substrate

Immune supportGut & microbiome