MycoData

RNase He1 from Hericium erinaceus, a member of the RNase T1 family, has high identity with RNase Po1 from Pleurotus ostreatus with complete conservation of the catalytic sequence..

Oncology

Medium relevance

Niu-Chang-Chih · 2015 · Research Support, Non U.S. Gov'T · BMC complementary and alternative medicine

Effects of Antrodia camphorata extracts on anti-oxidation, anti-mutagenesis and protection of DNA against hydroxyl radical damage.

BACKGROUND: Antrodia camphorata is a geographically special fungus and is one of the precious traditional medicines of Taiwan. A lot of reports have addressed its antioxidant activities and anticancer activities..

Oncology

Medium relevance

Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · Journal of natural products

Erinacerins C-L, isoindolin-1-ones with α-glucosidase inhibitory activity from cultures of the medicinal mushroom Hericium erinaceus.

The well-known edible and medicinal mushroom Hericium erinaceus produces various bioactive secondary metabolites. Ten new isoindolin-1-ones, named erinacerins C-L (1-10), together with (E)-5-(3,7-dimethylocta-2,6-dien-1-yl)-4-hydroxy-6-methoxy-2-phenethylisoindolin-1-one (11) were isolated from the solid culture of H..

Oncology

Medium relevance

Turkey Tail · 2015 · Research Support, Non U.S. Gov'T · Fitoterapia

Four new spiroaxane sesquiterpenes and one new rosenonolactone derivative from cultures of Basidiomycete Trametes versicolor.

Four new spiroaxane sesquiterpenes, tramspiroins A-D (1-4), one new rosenonolactone 15,16-acetonide (5), and the known drimane sesquiterpenes isodrimenediol (6) and funatrol D (7) have been isolated from the cultures of Basidiomycete Trametes versicolor..

Oncology

Medium relevance

Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Hericium erinaceus polysaccharide-protein HEG-5 inhibits SGC-7901 cell growth via cell cycle arrest and apoptosis.

HEG-5 is a novel polysaccharide-protein purified from the fermented mycelia of Hericium erinaceus CZ-2. The present study aims to investigate the effects of HEG-5 on proliferation, cell cycle and apoptosis of human gastric cancer cells SGC-7901..

OncologyImmune supportEnergy & fatigueGut & microbiome

Medium relevance

Almond Mushroom · 2015 · Research Support, Non U.S. Gov'T · BioMed research international

Immunomodulatory effects of the Agaricus blazei Murrill-based mushroom extract AndoSan in patients with multiple myeloma undergoing high dose chemotherapy and autologous stem cell transplantation: a randomized, double blinded clinical study.

Forty patients with multiple myeloma scheduled to undergo high dose chemotherapy with autologous stem cell support were randomized in a double blinded fashion to receive adjuvant treatment with the mushroom extract AndoSan, containing 82% of Agaricus blazei Murrill (19 patients) or placebo (21 patients)..

OncologyImmune support

Medium relevance

Turkey Tail · 2015 · Research Support, Non U.S. Gov'T · Chemosphere

Non conventional biological treatment based on Trametes versicolor for the elimination of recalcitrant anticancer drugs in hospital wastewater.

This work presents a study about the elimination of anticancer drugs, a group of pollutants considered recalcitrant during conventional activated sludge wastewater treatment, using a biological treatment based on the fungus Trametes versicolor..

OncologyEnergy & fatigue

Medium relevance

Mesima · 2015 · Research Support, Non U.S. Gov'T · Nutrition and cancer

Phellinus linteus extract induces autophagy and synergizes with 5-fluorouracil to inhibit breast cancer cell growth.

Phellinus linteus (PL) is a medicinal mushroom due to its several biological properties, including anticancer activity. However, the mechanisms of its anticancer effect remain to be elucidated..

Oncology

Medium relevance

Mesima · 2015 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Structural features and antitumor activity of a novel polysaccharide from alkaline extract of Phellinus linteus mycelia.

A novel high molecular weight polysaccharide (PL-N1) was isolated from alkaline extract of the cultured Phellinus linteus mycelia. The weight average molecular weight (Mw) of PL-N1 was estimated at 343,000kDa.

OncologyImmune supportMetabolic health

Medium relevance

Niu-Chang-Chih · 2015 · Research Support, Non U.S. Gov'T · BioMed research international

The Ethanolic Extract of Taiwanofungus camphoratus (Antrodia camphorata) Induces Cell Cycle Arrest and Enhances Cytotoxicity of Cisplatin and Doxorubicin on Human Hepatocellular Carcinoma Cells.

Taiwanofungus camphoratus (synonym Antrodia camphorata) is a widely used medicinal fungus in the folk medicine of Taiwan with several pharmacological features such as anti-inflammatory, liver protection, antihypertensive, and antioxidative activities. The ethanolic extract of T..

OncologyImmune supportMetabolic healthLiver support

Medium relevance

Maitake · 2014 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

A heteropolysaccharide, L-fuco-D-manno-1,6-α-D-galactan extracted from Grifola frondosa and antiangiogenic activity of its sulfated derivative.

The tumor growth and metastasis are angiogenesis dependent, thus blockade of angiogenesis is a promising approach for treatment of cancer. Herein we reported the structural and biological features of a novel water-soluble polysaccharide named GFPW from the fruit body of Grifola frondosa..

OncologyImmune support

Medium relevance

Enoki · 2014 · Research Support, Non U.S. Gov'T · Journal of immunology research

Activation effects of polysaccharides of Flammulina velutipes mycorrhizae on the T lymphocyte immune function.

Flammulina velutipes mycorrhizae have increasingly been produced with increasing of F. velutipes production.

OncologyImmune support

Medium relevance

Lion's Mane · 2014 · Research Support, Non U.S. Gov'T · Analytical and bioanalytical chemistry

Analysis of cyathane-type diterpenoids from Cyathus striatus and Hericium erinaceus by high-resolution MALDI MS imaging.

Fungal secondary metabolites in both fruiting bodies and pellets from submerged cultures of basidiomycetes were analyzed by atmospheric pressure matrix-assisted laser desorption/ionization-mass spectrometry imaging at a lateral resolution of 15 μm, a mass resolution of 140,000 at m/z 200 and a mass accuracy of better….

OncologyCognition & nerves

Medium relevance

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · Journal of natural products

Antcamphins A-L, ergostanoids from Antrodia camphorata.

Twelve ergostanoids, named antcamphins A-L (1-12), together with 20 known triterpenoids, were isolated from fruiting bodies of the medicinal fungus Antrodia camphorata. Compounds 1 and 2 represent the first examples of norergostanes isolated from A..

OncologyRespiratory

Medium relevance

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · Food & function

Anticancer effects on human pancreatic cancer cells of triterpenoids, polysaccharides and 1,3-β-D-glucan derived from the fruiting body of Antrodia camphorata.

Antrodia camphorata is a fungus native to Taiwan, and it is considered a precious medicinal agent. We analyzed triterpenoids, polysaccharides and 1,3-β-D-glucan, three major effective components in A.

OncologyImmune supportEnergy & fatigue

Medium relevance

Lion's Mane · 2014 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers.

ETHNOPHARMACOLOGICAL RELEVANCE: Hericium is a genus of mushrooms (fungus) in the Hericiaceae family. Hericium erinaceus (HE) has been used for the treatment of digestive diseases for over 2000 years in China..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · PloS one

Antimicrobial activity of Antrodia camphorata extracts against oral bacteria.

Antrodia camphorata (A. camphorata) is a unique, endemic and extremely rare mushroom species native to Taiwan, and both crude extracts of and purified chemical compounds from A.

OncologyImmune support

Medium relevance

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Antroquinonol D, isolated from Antrodia camphorata, with DNA demethylation and anticancer potential.

DNA methyltransferase 1 (DNMT1) catalyzes DNA methylation and is overexpressed in various human diseases, including cancer. A rational approach to preventing tumorigenesis involves the use of pharmacologic inhibitors of DNA methylation; these inhibitors should reactivate tumor suppressor genes (TSGs) in tumor cells….

OncologySkin & hydration

Medium relevance

Mesima · 2014 · Research Support, Non U.S. Gov'T · Journal of bioscience and bioengineering

Biological evaluation of Phellinus linteus-fermented broths as anti-inflammatory agents.

Phellinus linteus and its constituent hispolon induce potent anti-inflammatory activity in macrophages. Efficient production of the effective constituent and the biological function of P.

OncologyImmune support

Medium relevance

Enoki · 2014 · Research Support, Non U.S. Gov'T · Journal of the science of food and agriculture

Bioproduction of baccatin III, an advanced precursor of paclitaxol, with transgenic Flammulina velutipes expressing the 10-deacetylbaccatin III-10-O-acetyl transferase gene.

BACKGROUND: 10-Deacetylbaccatin III (10-DAB) and baccatin III are intermediates in the biosynthesis of Taxol (an anti-cancer drug) and useful precursors for semi-synthesis of the drug..

Oncology

Medium relevance

Chaga · 2014 · Research Support, Non U.S. Gov'T · Journal of natural products

Chemical constituents from Inonotus obliquus and their biological activities.

Seven new triterpenes, inonotusol A-G (1-7), one new diterpene, inonotusic acid (8), and 22 known compounds were isolated from Inonotus obliquus. Their structures were elucidated on the basis of spectroscopic analysis, including homonuclear and heteronuclear correlation NMR ((1)H-(1)H COSY, ROESY, HSQC, and HMBC)….

OncologyLiver support

Medium relevance

Niu-Chang-Chih · 2014 · Comparative Study · Phytomedicine: international journal of phytotherapy and phytopharmacology

Comparison of solid-state-cultured and wood-cultured Antrodia camphorata in anti-inflammatory effects using NF-κB/luciferase inducible transgenic mice.

PURPOSE: Antrodia camphorata (AC), a highly valued polypore mushroom native only to Taiwan, has been traditionally used as a medicine for the treatment of food and drug intoxication, diarrhea, abdominal pain, hypertension, skin itching, and cancer..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Wood Ear · 2014 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Dichlormethane extract of the jelly ear mushroom Auricularia auricula-judae (higher Basidiomycetes) inhibits tumor cell growth in vitro.

In this study, a dichloromethane fraction (DCMF) from 70% Auricularia auricula-judae ethanol extract showed the highest level of antitumor activity compared to other solvent fractions (ethyl acetate, butanol, and water)..

OncologyRespiratory

Medium relevance

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · TheScientificWorldJournal

Extract of Antrodia camphorata exerts neuroprotection against embolic stroke in rats without causing the risk of hemorrhagic incidence.

In this study, the neuroprotective effect of an extract of Antrodia camphorata (A. camphorata), a fungus commonly used in Chinese folk medicine for treatment of viral hepatitis and cancer, alone or in combination with aspirin was investigated in a rat embolic stroke model..

OncologyCognition & nervesLiver supportRespiratory

Medium relevance

Mesima · 2014 · Research Support, Non U.S. Gov'T · Chemico-biological interactions

Hispidin derived from Phellinus linteus affords protection against acrylamide-induced oxidative stress in Caco-2 cells.

Acrylamide (AA), a well-known toxicant, has attracted numerous attentions for its presumably carcinogenesis, neurotoxicity and cytotoxicity. Oxidative stress was considered to be associated with acrylamide cytotoxicity, but the link between oxidative stress and acrylamide cytotoxicity is still unclear..

OncologyCognition & nervesEnergy & fatigue

Medium relevance

Mesima · 2014 · Research Support, Non U.S. Gov'T · Phytomedicine: international journal of phytotherapy and phytopharmacology

Hispolon from Phellinus linteus possesses mediate caspases activation and induces human nasopharyngeal carcinomas cells apoptosis through ERK1/2, JNK1/2 and p38 MAPK pathway.

Hispolon, a phenol compound isolated from Phellinus linteus (PL), possesses anti-inflammatory, antiproliferative, and antioxidant effects. However, the effects of hispolon on human nasopharyngeal carcinomas have yet to be evaluated..

OncologyImmune support

Medium relevance

Chaga · 2014 · Research Support, Non U.S. Gov'T · International journal of oncology

Inonotus obliquus-derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9.

Polysaccharides isolated from the fruiting body of Inonotus obliquus (PFIO) are known to possess various pharmacological properties including antitumor activity. However, the anti-metastatic effect and its underlying mechanistic signaling pathway involved these polysaccharides in human non-small cell lung carcinoma….

OncologyImmune supportRespiratory

Medium relevance

Mesima · 2014 · Research Support, Non U.S. Gov'T · Journal of food science

Isolation, purification, and structural features of a polysaccharide from Phellinus linteus and its hypoglycemic effect in alloxan-induced diabetic mice.

Phellinus linteus is a medicinal mushroom that has been used in Oriental countries for centuries for its antitumor, antioxidant, immunomodulatory, and biological activity on hyperglycemia. A water-soluble crude polysaccharide was extracted using hot water from P.

OncologyImmune supportMetabolic health

Medium relevance

Zhu Ling · 2014 · Research Support, Non U.S. Gov'T · BMC complementary and alternative medicine

Khz-cp (crude polysaccharide extract obtained from the fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating P38 and NADPH oxidase-dependent generation of reactive oxygen species in SNU-1 cells.

BACKGROUND: Khz-cp is a crude polysaccharide extract that is obtained after nuclear fusion in Ganoderma lucidum and Polyporus umbellatus mycelia (Khz). It inhibits the growth of cancer cells.

OncologyImmune supportEnergy & fatigue

Medium relevance

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Methanol extract of Antrodia camphorata protects against lipopolysaccharide-induced acute lung injury by suppressing NF-κB and MAPK pathways in mice.

Antrodia camphorata (AC) has been used as a herbal medicine for drug intoxication for the treatment of inflammation syndromes and liver-related diseases in Taiwan. This study demonstrates the protective effect of the methanol extract of AC (MAC) on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice..

OncologyImmune supportEnergy & fatigueLiver support

Medium relevance

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · Molecules (Basel, Switzerland)

New and Cytotoxic Components from Antrodia camphorata.

The solid-state cultured products of Antrodia camphorata as health foods has been blooming for the past few decades in Taiwan. In continuing our studies on the chemical constituents of the solid-state cultured products of this fungus, 6-methoxy-4-methyl-2,3-(methylenedioxy)phenol (1) and….

Oncology

Medium relevance

Chaga · 2014 · Research Support, Non U.S. Gov'T · Oncology reports

Polysaccharide from Inonotus obliquus inhibits migration and invasion in B16-F10 cells by suppressing MMP-2 and MMP-9 via downregulation of NF-κB signaling pathway.

Polysaccharides derived from Inonotus obliquus (PIO) are known to possess multiple pharmacological activities including antitumor activity. However, the possible molecular mechanisms of these activities are unknown..

OncologyImmune supportEnergy & fatigue

Medium relevance

Enoki · 2014 · Research Support, Non U.S. Gov'T · Organic & biomolecular chemistry

Total synthesis of an anticancer norsesquiterpene alkaloid isolated from the fungus Flammulina velutipes.

The first total synthesis of a norsesquiterpene alkaloid (R)-8-hydroxy-4,7,7-trimethyl-7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione, isolated from the mushroom-forming fungus Flammulina velutipes, in both racemic and enantiomeric pure forms, is reported..

Oncology

Medium relevance

Niu-Chang-Chih · 2013 · Research Support, Non U.S. Gov'T · Carcinogenesis

A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.

Lung cancer is the leading cause of cancer deaths worldwide and current therapies fail to treat this disease in majority of cases. Antrodia camphorata is a medicinal mushroom being widely used as food dietary supplement for cancer prevention..

OncologyImmune supportGut & microbiomeSkin & hydration

Medium relevance

Mesima · 2013 · Research Support, Non U.S. Gov'T · Chemico-biological interactions

Activation of P27kip1-cyclin D1/E-CDK2 pathway by polysaccharide from Phellinus linteus leads to S-phase arrest in HT-29 cells.

Our previous study showed that polysaccharide (P1) from Phellinus linteus exhibits a significant inhibitive activity on human colorectal carcinoma cells (HT-29). However its novel molecular mechanism remains unknown..

OncologyImmune supportMetabolic healthLiver support

Medium relevance

Niu-Chang-Chih · 2013 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from Antrodia camphorata on the inflammatory mediator expression in mice.

Eburicoic acid (TR1) and dehydroeburicoic acid (TR2), an active ingredient from Antrodia camphorata (AC) solid-state culture, were evaluated for analgesic and anti-inflammatory effects..

OncologyImmune support

Medium relevance

Chaga · 2013 · Research Support, Non U.S. Gov'T · Food chemistry

Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus.

Mushroom Inonotus obliquus (I. obliquus) has been used as functional food and traditional Chinese herbs for long time.

OncologyImmune support

Medium relevance

Niu-Chang-Chih · 2013 · Research Support, Non U.S. Gov'T · Journal of medicinal food

Antrodia camphorata grown on germinated brown rice inhibits HT-29 human colon carcinoma proliferation through inducing G0/G1 phase arrest and apoptosis by targeting the β-catenin signaling.

Antrodia camphorata (AC) has been used as a traditional medicine to treat food and drug intoxication, diarrhea, abdominal pain, hypertension, pruritis (skin itch), and liver cancer in East Asia..

OncologyEnergy & fatigueMetabolic healthGut & microbiome

Medium relevance

Chaga · 2013 · Research Support, Non U.S. Gov'T · Molecules (Basel, Switzerland)

Bioassay-guided isolation of DPP-4 inhibitory fractions from extracts of submerged cultured of Inonotus obliquus.

Inonotus obliquus is a medicinal mushroom used in Russian and Eastern European folk medicine for the treatment of gastrointestinal cancer, cardiovascular disease and diabetes. Previous studies in our laboratory have demonstrated that the mycelium powders of I..

OncologyMetabolic healthGut & microbiome

Medium relevance

Niu-Chang-Chih · 2013 · Research Support, Non U.S. Gov'T · The American journal of Chinese medicine

Cytotoxic effect and induction of apoptosis in human cervical cancer cells by Antrodia camphorata.

Antrodia camphorata is a Chinese herb indigenous to Taiwan. Previous reports demonstrated that it could induce apoptosis in some cancer cells.

Oncology

Medium relevance

Enoki · 2013 · Research Support, Non U.S. Gov'T · International journal of pharmaceutics

Cytotoxic effect of novel Flammulina velutipes sterols and its oral bioavailability via mixed micellar nanoformulation.

The aim of this study was to investigate the anti-tumor effect of sterols initially separated from Flammulina velutipes and the pharmacokinetics and tissue distribution after oral administration of F. velutipes sterol nanomicelles (FVSNs).

OncologyLiver support

Medium relevance

Enoki · 2013 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Enhanced oral bioavailability and tissue distribution of a new potential anticancer agent, Flammulina velutipes sterols, through liposomal encapsulation.

This study innovatively investigated the anticancer effect of Flammulina velutipes sterols (FVSs), the in vivo pharmacokinetics, and the tissue distribution of FVS-loaded liposomes..

OncologyLiver supportRespiratory

Medium relevance

Enoki · 2013 · Research Support, Non U.S. Gov'T · Journal of biotechnology

Functional expression of FIP-fve, a fungal immunomodulatory protein from the edible mushroom Flammulina velutipes in Pichia pastoris GS115.

FIP-fve is a bioactive protein isolated from the mushroom Flammulina velutipes, which belongs to the fungal immunomodulatory protein (FIP) family and demonstrates several kinds of biological activities including anti-allergy, anti-tumor and immunomodulation..

OncologyImmune support

Medium relevance

Niu-Chang-Chih · 2013 · Research Support, Non U.S. Gov'T · Food chemistry

Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury.

The hepatoprotective effects of eburicoic acid (TR1) and dehydroeburicoic acid (TR2) from Antrodia camphorata (AC) against carbon tetrachloride (CCl4)-induced liver damage were investigated in mice. TR1 and TR2 was administered intraperitoneally (i.p.) for 7 days prior to the administration of CCl4..

OncologyImmune supportEnergy & fatigueLiver support

Medium relevance

Mesima · 2013 · Research Support, Non U.S. Gov'T · The American journal of Chinese medicine

Hispolon from Phellinus linteus induces G0/G1 cell cycle arrest and apoptosis in NB4 human leukaemia cells.

Hispolon (a phenolic compound isolated from Phellinus linteus) has been shown to possess strong antioxidant, anti-inflammatory, anticancer, and antidiabetic properties..

OncologyImmune supportMetabolic healthLiver support

Medium relevance

Mesima · 2013 · Research Support, Non U.S. Gov'T · Asian Pacific journal of tropical biomedicine

Identification of an anticancer compound against HT-29 cells from Phellinus linteus grown on germinated brown rice.

OBJECTIVE: To isolate and identify the anticancer compound against proliferation of human colon cancer cells from ethyl acetate (EtOAc) extract of Phellinus linteus grown on germinated brown rice (PB). METHODS: EtOAc extract of PB was partitioned with n-hexane, EtOAc, and water-saturated n-butanol..

OncologyGut & microbiome

Medium relevance

Maitake · 2013 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Inducement of cytokine release by GFPBW2, a novel polysaccharide from fruit bodies of Grifola frondosa, through dectin-1 in macrophages.

Polysaccharides, especially β-glucans isolated from various species of mushrooms, are considered as biological response modifiers (BRMs) to be widely used in the treatment of cancer, especially due to their immunostimulatory activity..

OncologyImmune support

Medium relevance

Yellow Morel · 2013 · Research Support, Non U.S. Gov'T · Biotechnology letters

Induction of apoptosis in HepG2 cells by polysaccharide MEP-II from the fermentation broth of Morchella esculenta.

A novel polysaccharide, MEP-II, isolated from the fermentation broth of Morchella esculenta inhibited the proliferation of human hepatoma cell line (HepG2) through an apoptotic pathway..

OncologyImmune supportEnergy & fatigueLiver support

Medium relevance

Chaga · 2013 · Research Support, Non U.S. Gov'T · Molecular medicine reports

Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation.

Low molecular weight (LMW) polyphenolics containing a polyhydroxylated benzyl moiety are abundant in medicinal plants. In the present study, we report on the activities of seven LMW polyphenolics isolated from Inonotus obliquus, a medicinal mushroom..

OncologyMetabolic healthGut & microbiome

Medium relevance

Enoki · 2013 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Interruption of lung cancer cell migration and proliferation by fungal immunomodulatory protein FIP-fve from Flammulina velutipes.

FIP-fve is an immunomodulatory protein isolated from Flammulina velutipes that possesses anti-inflammatory and immunomodulatory activities. However, little is known about its anticancer effects.

OncologyImmune supportSkin & hydrationRespiratory