MycoData

Metadata-grounded summary: This patent indexes research on Phellinus linteus in 2006. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..

Oncology

Medium relevance

Mesima · 2006 · Patent · journal metadata

THE METHOD FOR MAKING FUNCTIONAL FISHES USING PHELLINUS LINTEUS AND PRODUCT THEREOF

Oncology

Medium relevance

Mesima · 2006 · Patent · journal metadata

THE METHOD FOR MAKING THE KOREAN TRADITIONAL CONFECTIONERY USING PHELLINUS LINTEUS AND PRODUCT THEREOF

Oncology

Medium relevance

Reishi · 2026 · Research Article · The Journal of clinical investigation

A fungi-derived cyclic peptide enhances Th9-mediated antitumor immunity by targeting ZAP70 and SREBP1.

Adoptive cell therapy (ACT) relies on durable and functional T cells to mediate tumor clearance. Th9 cells are a metabolically fit CD4+ T cell subset with strong persistence but limited cytotoxicity..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Reishi · 2026 · Research Article · Current issues in molecular biology

A Water Extract of Mixed Mushroom Mycelia Mitigates Cognitive Deficit and Oxidative Stress After Global Cerebral Ischemia-Reperfusion Injury.

BACKGROUND: GMK is a bioactive material newly identified from a water extract of mixed mushroom mycelia (Phellinus linteus, Inonotus obliquus, and Ganoderma lucidum). It has shown protective effects against glutamate-induced excitotoxicity and lipopolysaccharide-triggered neuroinflammation..

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Reishi · 2026 · Research Article · Biochemistry and biophysics reports

Comprehensive evaluation of sacchachitosan-based transdermal films for wound care: Physical, chemical, and biological parameters.

In the present investigation, the development and comparative assessment of sacchachitosan-based transdermal films loaded with biosynthesized silver nanoparticles (AgNPs) for wound-healing applications were reported..

OncologySkin & hydration

Medium relevance

Niu-Chang-Chih · 2026 · Journal Article · European journal of pharmacology

Ergostatrien-3β-ol suppresses breast cancer anoikis resistance and metastasis by targeting the miR-93-5p/leupaxin axis.

Breast cancer is the malignancy most frequently diagnosed among women and ranks as a top cause of cancer-related deaths globally, with distant metastasis being the main factor behind these fatalities..

OncologyImmune support

Medium relevance

Reishi · 2026 · Journal Article · Journal of ethnopharmacology

Ganoderic Acid A alleviates ulcerative colitis by inhibiting the interleukin17 signaling pathway via targeting retinoic acid-related orphan receptor alpha.

ETHNOPHARMACOLOGICAL RELEVANCE: Ulcerative colitis (UC), a chronic inflammatory bowel disease, poses a significant global public health burden, a challenge compounded by the limited availability of effective treatments..

OncologyImmune supportGut & microbiome

Medium relevance

Reishi · 2026 · Research Article · Current issues in molecular biology

Ganoderic Acid A Attenuates Pathological Cardiac Hypertrophy by Attenuating Inflammatory Responses.

Pathological cardiac hypertrophy is an important risk factor for cardiovascular disease. Ganoderic acid A (GAA), the primary bioactive constituent of Ganoderma lucidum (G.

OncologyImmune support

Medium relevance

Reishi · 2026 · Journal Article · Carbohydrate polymers

Identification of multiple galectins as receptors for β-1,3-glucans.

β-1,3-glucans are natural polysaccharides widely distributed in bacterial capsules and fungal cell walls. β-1,3-glucans are potent immunomodulators traditionally recognized by receptors like Dectin-1 and CD204, yet the complete receptor repertoire has remained ill-defined..

OncologyImmune support

Medium relevance

Cordyceps · 2026 · Journal Article · International journal of medicinal mushrooms

Immunomodulatory Effects of Medicinal Mushroom Extracts in the Sensitized Human Keratinocyte Cell Line NCTC2544.

Contact dermatitis (CD) is a common skin condition characterized by inflammation caused by exposure to allergens. In Malaysia, it accounts for a significant portion of skin diseases, with irritant contact dermatitis being the most prevalent type..

OncologyImmune supportEnergy & fatigueSkin & hydration

Medium relevance

Reishi · 2026 · Journal Article · Proteins

In Silico and In Vitro Analysis of Ganoderic Acid A Binding to Human Monocarboxylate Transporters 1 and 4.

In recent years, the search for novel anticancer agents has increasingly focused on monocarboxylate transporters (MCTs) because of their involvement in tumor metabolism..

Oncology

Medium relevance

Reishi · 2026 · Research Article · International journal of molecular sciences

In Vitro Anti-Glioblastoma Activity of a Novel Pt(IV)-Ganoderic Acid A Conjugate.

Glioblastoma is the most aggressive primary malignant tumor of the central nervous system in adults, with a poor prognosis and high resistance to conventional therapies. Platinum drugs like cisplatin are effective but limited by systemic toxicity, poor blood-brain barrier penetration, and resistance..

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Oyster Mushroom · 2026 · Journal Article · Probiotics and antimicrobial proteins

Integration of Conjugated Linoleic Acid-Producing Probiotic Strains Having Anti-adipogenic Properties with Honey and Oyster Mushrooms for the Formulation of Non-dairy Probiotic Beverage.

Conjugated linoleic acid (CLA) has been linked to various health benefits, including anti-cancer, anti-diabetic, and anti-obesity effects. Obesity, marked by abnormal fat deposition, increases the risk of metabolic disorders such as cardiovascular diseases and type-2 diabetes..

OncologyMetabolic healthGut & microbiome

Medium relevance

Turkey Tail · 2026 · Journal Article · Fitoterapia

MALDI-MSI spatial mapping of phenanthrenes in Bletilla striata leaves uncovers BsLAC1 as the first laccase catalysing phenanthrene dimerisation.

Bletilla striata, a traditional Chinese medicinal herb, is particularly rich in phenanthrenes and their dimers, which exhibit anti-inflammatory, antibacterial, and antitumor properties..

OncologyImmune support

Medium relevance

Reishi · 2026 · Research Article · Frontiers in pharmacology

Multi-omics integration identifies ganoderic acid A as a TNFα inhibitor for treating sepsis-related liver injury.

Ganoderic acid A (GAA), a major bioactive triterpenoid from Ganoderma lucidum, is known for its anti-inflammatory effects; however, its precise molecular targets in sepsis-related liver injury (SRLI) remain unclear..

OncologyImmune supportLiver support

Medium relevance

Cordyceps · 2026 · Journal Article · Applied biochemistry and biotechnology

Ophiocordyceps indica from the Indian Himalayas Ameliorates the IgA Nephropathy in Mice.

Immunoglobulin A nephropathy (IgAN) is the most common form of chronic glomerulonephritis and a major cause of end-stage renal disease worldwide, currently lacks safe, effective therapies. Ophiocordyceps sinensis, a well-known traditional medicinal fungus and used for treating kidney-related disorders..

OncologyImmune support

Medium relevance

Turkey Tail · 2026 · Journal Article · Bioorganic & medicinal chemistry

Synthesis and biological evaluation of novel C1 or C3 amino derivatives of A-ring 1,2,3-trisubstituted 19-nor-vitamin D3.

Two new analogs of 1α,25-dihydroxy-19-nor-vitamin D3 with an additional hydroxyl group at position 2 and an amino group at C1 or C3 using quinic acid as starting substrate for the A-ring precursor are described..

Oncology

Medium relevance

Reishi · 2026 · Journal Article · International journal of biological macromolecules

Targeting HSP90 destabilization with ganoderic acid a as a novel therapeutic strategy for hepatoblastoma.

BACKGROUND: Hepatoblastoma (HB) is the most prevalent primary liver malignancy in children and is characterized by aggressive progression and suboptimal therapeutic outcomes..

OncologyLiver support

Medium relevance

Agarikon · 2025 · Journal Article · International journal of biological macromolecules

A TME-responsive polysaccharide nanoplatform integrating synergetic therapy for cancer.

A self-assembling nanoplatform based on FOB (a heteropolysaccharide from Fomitopsis officinalis) named QU@FOB-FcDBA was developed in this study. A dynamic boronate ester bond, a pH-sensitive covalent linkage formed through reversible dehydration reactions, linked FOB and 1,1'-ferrocenediboronic acid (FcDBA) while….

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Turkey Tail · 2025 · Journal Article · International journal of medicinal mushrooms

Analysis of Antioxidant and Anticancer Activities of Selected Trametes Species (Agaricomycetes) from Iran.

The remarkable spectrum of bioactive compounds in medicinal mushrooms makes them an excellent source for treating a variety of diseases. Among these, Trametes Fr.

OncologyImmune supportMetabolic health

Medium relevance

Reishi · 2025 · Journal Article · International journal of molecular sciences

Antrodia cinnamomea Formula Suppresses Prostate Cancer Progression via Immune Modulation and PD-1/PD-L1 Pathway Inhibition.

Prostate cancer remains a significant global health challenge, necessitating the development of novel therapeutic approaches. This study investigated the therapeutic potential of the Antrodia cinnamomea formula (XIANZHIFANG formula, XZF), comprising Antrodia cinnamomea, Sanghuangporus sanghuang, Ganoderma lucidum,….

OncologyImmune support

Medium relevance

Niu-Chang-Chih · 2025 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Antroquinonol mitigates Tau hyperphosphorylation, neuronal damage and cognitive impairments in a chronic cerebral ischemia rat model.

Chronic cerebral ischemia (CCI) induced hyperphosphorylated Tau has been associated with an increased risk of neurodegenerative disorders such as Alzheimer's and vascular dementia..

OncologyImmune supportCognition & nervesMetabolic health

Medium relevance

Oyster Mushroom · 2025 · Research Article · Toxins

Biocatalytic Detoxification of Ochratoxins A/B by a Fungal Dye-Decolorizing Peroxidase: Mechanistic Insights and Toxicity Assessment.

Mycotoxin contamination in agricultural products poses severe global health risks, with ochratoxins (particularly OTA and OTB) exhibiting marked nephrotoxicity and classified as Group 2B carcinogens by IARC..

Oncology

Medium relevance

Reishi · 2025 · Research Article · Current issues in molecular biology

Biomarker Discovery and Molecular Docking Reveal Marsdenia tenacissima Fermentation Product's Anti-Lung Cancer Components.

In traditional Chinese medicine, Marsdenia tenacissima is employed to prevent and treat lung cancer. The anti-tumor properties are further amplified by the fermentation product of Ganoderma lucidum and Marsdenia tenacissima (MGF)..

OncologyRespiratory

Medium relevance

Shiitake · 2025 · Research Article · Genes

Characterization and Expression Analysis of the bHLH Gene Family During Developmental Stages and Under Various Abiotic Stresses in Sanghuangporus baumii.

BACKGROUND: Basic helix-loop-helix (bHLH) transcription factors (TFs) widely exist in eukaryotic organisms and play a key role in plant growth and development in response to environmental stresses..

OncologyLiver support

Medium relevance

Oyster Mushroom · 2025 · Research Article · BMC complementary medicine and therapies

Computational development of mushroom-6-glucan/paclitaxel as a synergistic complementary medicine for breast cancer therapy.

BACKGROUND: Breast cancer is chemo-resistant and highly metastatic, often resulting in patient mortality. One of the primary factors contributing to the metastasis and chemotherapy resistance is the presence of cancer stem-like cells..

OncologyImmune supportEnergy & fatigueGut & microbiome

Medium relevance

Niu-Chang-Chih · 2025 · Research Article · Molecular medicine reports

Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.

Atherosclerosis (AS)‑related coronary artery disease is the main cause of morbidity and mortality around the globe. Eburicoic acid, a triterpenoid compound from Antrodia camphorata, exerts anti‑inflammatory and anti‑hyperlipidemic effects, although its role in atherogenesis remains unknown..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Reishi · 2025 · Journal Article · International journal of biological macromolecules

Effects of Ganoderma spent substrate containing with polysaccharides and triterpenoids on the growth performance, antioxidant capacity and immunity level of chickens.

Ganoderma spent substrate (GSS) is the residual material of Ganoderma lucidum (GL) cultivation, which has abundant polysaccharides and triterpenoids. GL is widely recognized for its antioxidant and immune-boosting properties, however, the effects of GSS remain largely unexplored..

OncologyImmune supportEnergy & fatigueSkin & hydration

Medium relevance

Reishi · 2025 · Journal Article · Biotechnology and applied biochemistry

Elucidating the protective mechanism of ganoderic acid DM on breast cancer based on network pharmacology and in vitro experimental validation.

Ganoderma lucidum, a popular medicinal fungus, has been utilized to treat a variety of diseases. It possesses a unique therapeutic and pharmacological reputation in suppressing cancer/tumor progression, especially breast cancer, due to its embedded rich bioactive chemical constituents, mainly triterpenoids (ganoderic….

OncologySkin & hydration

Medium relevance

Oyster Mushroom · 2025 · Research Article · Current issues in molecular biology

Enzymatic Activity and Nutrient Profile Assessment of Three Pleurotus Species Under Pasteurized Cenchrus fungigraminus Cultivation.

Oyster mushrooms are regarded as one of the most significant edible mushrooms in terms of commercial value because of their rich nutritional profile. Many bioactive extracts from Pleurotus species have been found to exhibit antitumor and antioxidant activities..

OncologyEnergy & fatigue

Medium relevance

Reishi · 2025 · Research Article · Frontiers in pharmacology

Evaluation of in vitro pharmacological activities of medicinal mushrooms in the context of dry eye disease.

INTRODUCTION: Ethnic groups worldwide use mushrooms, particularly polypores (a group of fungi with woody fruiting bodies), to manage inflammatory conditions. In this study, the in vitro anti-inflammatory potential and mycochemical composition of six polypore extracts derived from the fruit bodies of Fomes fomentarius….

OncologyImmune supportEnergy & fatigueSkin & hydration

Medium relevance

Lion's Mane · 2025 · Research Article · Foods (Basel, Switzerland)

Exploring the Nutraceutical Potential of a Food-Medicine Compound for Metabolic-Associated Fatty Liver Disease via Lipidomics and Network Pharmacology.

Metabolic-associated fatty liver disease (MAFLD) is a prevalent global health issue closely tied to dietary habits, impacting a significant portion of the adult population..

OncologyImmune supportMetabolic healthLiver support

Medium relevance

Reishi · 2025 · Journal Article · International journal of medicinal mushrooms

Fatty Acid Determination and Activity Evaluation of Wild Higher Fungi from Southern Sichuan, China.

To study the species composition and resource value of wild higher fungi, 29 mushrooms were collected in southern Sichuan, China. The antioxidant activity was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), and total reducing power..

Oncology

Medium relevance

Lion's Mane · 2025 · Journal Article · Histology and histopathology

Galangin alleviates gastric mucosal injury in rats with chronic atrophic gastritis by reducing ferroptosis.

OBJECTIVE: Chronic atrophic gastritis (CAG) is a precancerous lesion and is the first stage in a multistep precancerous cascade that can lead to gastric adenocarcinoma. This study aimed to reveal the role and mechanism of galangin in CAG..

OncologyImmune supportEnergy & fatigue

Medium relevance

Reishi · 2025 · Journal Article · World journal of surgical oncology

Ganoderic acid a potentiates cisplatin's cytotoxicity on gallbladder cancer cells by promoting DNA damage and inhibiting cell stemness.

BACKGROUND: Ganoderma acid A (GAA), a triterpenoid compound from Ganoderma lucidum, has gained attention for its anti-tumor properties. Herein, we hypothesized that GAA may enhance cisplatin's (DDP) anticancer effect in gallbladder cancer (GBC) cells by promoting DNA damage response, particularly through upregulation….

OncologyImmune supportGut & microbiome

Medium relevance

Reishi · 2025 · Journal Article · International immunopharmacology

Ganoderic acid A regulates CSF1R to reprogram tumor-associated macrophages for immune therapy of hepatocellular carcinoma.

BACKGROUND: The tumor microenvironment (TME) plays a crucial role in cancer progression, with tumor-associated macrophages (TAMs) constituting the core cell population of the tumor immune microenvironment. TAMs can differentiate into M1 or M2 types based on the TME, either inhibiting or promoting tumor development..

OncologyImmune supportLiver support

Medium relevance

Oyster Mushroom · 2025 · Research Article · Biotechnology and bioengineering

Gold Nanoparticles Coated With Hydrophobin-ProteinA Fusion Protein: Development of a Versatile Immunosensing Platform.

Advancing immunosensing technologies hinges on the development of next-generation surface functionalization methods, as the precise anchoring of antibodies on transducer interface is essential for achieving high sensitivity and selectivity..

OncologyImmune supportEnergy & fatigueRespiratory

Medium relevance

Zhu Ling · 2025 · Journal Article · Journal of ethnopharmacology

Injinoryeong-San attenuates metabolic dysfunction-associated steatohepatitis via regulation of YAP/TAZ-signaling pathway.

ETHNOPHARMACOLOGICAL RELEVANCE: Injinoryeong-san (IJO), known as Yinchen-Wuling Powder in Chinese medicine, is a traditional herbal formula comprising six herbal medicinal plants, including Atractylodes macrocephala Koidz., Polyporus umbellatus (Pers.) Fries, Poria cocos (Schw.) Wolf, Cinnamomum cassia Presl, Alisma….

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Almond Mushroom · 2025 · Research Article · Digestive diseases and sciences

LeLISA: A New Lectin-Based Immunoassay for Evaluation of Mucinous and Serous Content in Pancreatic Cystic Neoplasms.

BACKGROUND: The discrimination of mucinous from serous pancreatic cysts and pseudocysts is an important clinical issue. We aimed to investigate the possibility of using our LeLISA test for distinguishing between different types of pancreatic cysts..

OncologyImmune supportGut & microbiome

Medium relevance

Shiitake · 2025 · Journal Article · International Journal of Biological Macromolecules

Lentinan attenuates histone deacetylation of SOCS1 promoter to remodel autophagy via JAK2/STAT3 pathway for the prevention of intervertebral disc degeneration

Intervertebral disc degeneration (IVDD), driven by nucleus pulposus cell (NPCs) apoptosis, extracellular matrix (ECM) dyshomeostasis, and inflammation, lacks effective therapies. Lentinan (LNT), a polysaccharide from lentinula edodes, has anti-inflammatory and antioxidant properties..

OncologyImmune supportEnergy & fatigue

Medium relevance

Shiitake · 2025 · Journal Article · International journal of biological macromolecules

Lentinan attenuates histone deacetylation of SOCS1 promoter to remodel autophagy via JAK2/STAT3 pathway for the prevention of intervertebral disc degeneration.

OncologyImmune supportEnergy & fatigue

Medium relevance

Shiitake · 2025 · Research Article · Frontiers in immunology

Lentinan enhances CAR-T cell potency in solid tumors by optimizing T cell differentiation.

CAR-T cell therapy has demonstrated remarkable success in treating hematologic malignancies; however, its efficacy in solid tumors remains constrained. In this study, we demonstrate that Lentinan (LTN), an active polysaccharide derived from Lentinula edodes, potently enhances CAR-T cell function against solid tumors..

OncologyImmune supportCognition & nervesGut & microbiome

Medium relevance

Agarikon · 2025 · Journal Article · ACS applied bio materials

Natural Flavonoid and Fungal Polysaccharide-Based Redox-Responsive Nanogels for Synergistic Tumor Chemo-Immunotherapy.

Cancer remains a leading cause of global mortality, underscoring the urgent need for safe, effective, and innovative therapeutic strategies. Nanotechnology, particularly nanogels, offers promising opportunities for cancer treatment..

OncologyImmune support

Medium relevance

Snow Fungus · 2025 · Research Article · Foods (Basel, Switzerland)

Natural Tremella Polysaccharide Mitigates DEHP-Induced Oxidative Stress and Apoptosis via Dual Regulation of Survival and Antioxidant Pathways.

Diethylhexyl phthalate (DEHP), a common environmental plasticizer, induces oxidative damage and cell apoptosis without efficient treatment. Tremella fuciformis polysaccharides (TFPs) are known natural antioxidants, yet their protection against DEHP toxicity remains unclear..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Reishi · 2025 · Research Article · International journal of molecular sciences

Network Pharmacology and Bioinformatics Study of Six Medicinal Food Homologous Plants Against Colorectal Cancer.

Integrating network pharmacological analysis and bioinformatic techniques, this study systematically investigated the molecular mechanisms of six medicinal food homologous plants (Astragalus membranaceus, Ganoderma lucidum, Dioscorea opposite, Curcuma longa, Glycyrrhiza uralensis, and Pueraria lobata) against….

OncologyImmune supportCognition & nerves

Medium relevance

Zhu Ling · 2025 · Research Article · International journal of molecular sciences

Polyporusterone B Alleviates Inflammatory Injury via Suppression of Pro-Inflammatory Cytokine Production.

Polyporusterone B, a triterpene carboxylic acid isolated from Polyporus umbellatus Fries, exhibits anti-cancer and anti-hemolytic activities; however, its anti-inflammatory properties and underlying mechanisms remain unelucidated..

OncologyImmune supportLiver supportRespiratory

Medium relevance

Reishi · 2025 · Research Article · Food science & nutrition

Protective Effects of Ganoderma Triterpenoids Supplementation Against Myocardial Injury in Exhaustion Exercise Mice via Regulation of the Keap1/Nrf2/HO-1 Pathway.

Exhaustive physical exercise, while promoting cardiovascular fitness, can paradoxically lead to excessive oxidative stress, systemic fatigue, and myocardial injury. Despite increasing awareness of exhaustion exercise myocardial damage, effective preventive strategies remain limited..

OncologyEnergy & fatigue

Medium relevance

Reishi · 2025 · Journal Article · Food Research International

Radioprotective effect of edible and medicinal mushrooms against ionizing radiation: Components, potential mechanisms, and applications

Ionizing radiation can cause severe damage to the body. The use of natural products as radioprotective agents has gained increasing popularity and attention in recent years..

OncologyImmune support

Medium relevance

Oyster Mushroom · 2025 · Research Article · Molecules (Basel, Switzerland)

Solid-State Fermentation of Riceberry Rice with Mushroom Mycelium for Enhanced Beta-Glucan Production and Health Applications.

Beta-glucans (β-glucans), polysaccharides found in cereals and fungi, are recognized for their prebiotic and potential anti-cancer activities, particularly in the colorectal area..

OncologyImmune supportEnergy & fatigueGut & microbiome