MycoData

Metabolic healthRespiratory

Oyster Mushroom · 2024 · Research Article · International journal of molecular sciences

Transcriptome Analysis Reveals the Effect of Oyster Mushroom Spherical Virus Infection in Pleurotus ostreatus.

Oyster mushroom spherical virus (OMSV) is a mycovirus that inhibits mycelial growth, induces malformation symptoms, and decreases the yield of fruiting bodies in Pleurotus ostreatus. However, the pathogenic mechanism of OMSV infection in P.

Snow Fungus · 2024 · Research Article · BMC nutrition

Tremella fuciformis beverage improves glycated hemoglobin A1c and waist circumference in overweight/obese prediabetic subjects: a randomized controlled trial.

BACKGROUND: Prediabetes is increasing worldwide. Previous studies have demonstrated the potential of β-glucan derived from oat or barley to lower blood glucose, body weight, and plasma lipid levels.

Immune supportMetabolic healthSkin & hydration

Cordyceps · 2024 · Research Article · Molecules (Basel, Switzerland)

Ultrasound-Assisted Enzyme Extraction, Physicochemical Properties and Antioxidant Activity of Polysaccharides from Cordyceps militaris Solid Medium.

Cordyceps militaris solid medium polysaccharides (CMMPs) were extracted using an ultrasound-assisted enzyme method, and the process conditions were optimized via response surface methodology (RSM)..

Chaga · 2023 · Review · Journal of inflammation research

Research Progress on Application of Inonotus obliquus in Diabetic Kidney Disease.

Diabetic kidney disease (DKD) is one of the prime causes of end-stage renal disease. At present, the treatment of DKD is mainly confined to inhibiting the renin-angiotensin-aldosterone system, but the therapeutic effects is not satisfactory..

Cordyceps · 2023 · Meta-Analysis · Phytomedicine: international journal of phytotherapy and phytopharmacology

The effects of Ophiocordyceps sinensis combined with ACEI/ARB on diabetic kidney disease: A systematic review and meta-analysis.

BACKGROUND: Ophiocordyceps sinensis (OS), a medicinal fungus, has been made into OS preparations, which are frequently used as adjunctive therapy for patients with Diabetic Kidney Disease (DKD) in China..

Cordyceps · 2022 · Review · Mycobiology

Comprehensive Transcriptomic Analysis of Cordyceps militaris Cultivated on Germinated Soybeans.

The ascomycete fungus Cordyceps militaris infects lepidopteran larvae and pupae and forms characteristic fruiting bodies. Owing to its immune-enhancing effects, the fungus has been used as a medicine.

OncologyImmune supportMetabolic healthLiver support

Almond Mushroom · 2022 · Review · Current research in food science

Critical review on chemical compositions and health-promoting effects of mushroom Agaricus blazei Murill.

Agaricus blazei Murrill (AbM) is a medical mushroom which has huge potential commercial value with various health-promoting functions. However, the chemical composition and therapeutic mechanisms of AbM have not been concluded systematically yet..

Energy & fatigueMetabolic health

Oyster Mushroom · 2022 · Randomized Controlled Trial · International journal of medicinal mushrooms

Dietary Supplementation with Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), Reduces Visceral Fat and Hyperlipidemia in Inhabitants of a Rural Community in Mexico.

The abandonment of traditional foods in the Mexican diet is one of the causes for the increase in diseases associated with obesity. Edible mushrooms have been a part of the Mexican diet since pre-Hispanic times..

OncologyImmune supportCognition & nervesMetabolic health

Reishi · 2022 · Review · Frontiers in pharmacology

Ganoderma lucidum: Unutilized natural medicine and promising future solution to emerging diseases in Africa.

Ganoderma lucidum is a well-known medicinal mushroom that has been used for the prevention and treatment of different ailments to enhance longevity and health specifically in China, Japan, and Korea..

King Oyster · 2022 · Randomized Controlled Trial · Pharmacological research

Pleurotus eryngii improves postprandial glycaemia, hunger and fullness perception, and enhances ghrelin suppression in people with metabolically unhealthy obesity.

The aim of this study was to examine potential postprandial benefits of Pleurotus eryngii in nineteen volunteers with metabolically unhealthy obesity. An acute, randomized, crossover-designed trial comparing a meal with Pleurotus eryngii and a control meal was performed..

Cordyceps · 2022 · Review · Frontiers in nutrition

Structural Elucidation and Activities of Cordyceps militaris-Derived Polysaccharides: A Review.

Cordyceps militaris is a parasitic edible fungus and has been used as tonics for centuries. Polysaccharides are a major water-soluble component of C.

OncologyImmune supportCognition & nervesMetabolic health

Reishi · 2022 · Review · The American journal of Chinese medicine

The Pharmacological Rationales and Molecular Mechanisms of Ganoderma lucidum Polysaccharides for the Therapeutic Applications of Multiple Diseases.

As a versatile Chinese herb, Ganoderma lucidum (Leyss. ex Fr.) Karst (G.

OncologyImmune supportCognition & nervesMetabolic health

Reishi · 2021 · Review · Phytotherapy research: PTR

Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and toxicological properties.

Reishi owes an exceptional value in nutritional, cosmeceutical, and medical treatments; however, none of the studies has provided its future-driven critical assessment..

Immune supportCognition & nervesMetabolic health

Reishi · 2021 · Review Article · Nutrients

Health-Promoting of Polysaccharides Extracted from Ganoderma lucidum.

Medicinal mushrooms are rich sources of pharmacologically active compounds. One of the mushrooms commonly used in traditional Chinese medicine is Ganoderma lucidum (Leyss.

Shiitake · 2021 · Randomized Controlled Trial · European journal of nutrition

Modulation of human intestinal microbiota in a clinical trial by consumption of a β-D-glucan-enriched extract obtained from Lentinula edodes.

PURPOSE: The aim of this study was to evaluate the hypocholesterolemic, immune- and microbiota-modulatory effect of a mushroom extract in hypercholesterolemic subjects..

OncologyImmune supportMetabolic healthRespiratory

Cordyceps · 2021 · Review · Frontiers in bioengineering and biotechnology

New Insights Into the Biosynthesis of Typical Bioactive Components in the Traditional Chinese Medicinal Fungus Cordyceps militaris.

Cordyceps militaris, a traditional medicinal ingredient with a long history of application in China, is regarded as a high-value fungus due to its production of various bioactive ingredients with a wide range of pharmacological effects in clinical treatment..

OncologyImmune supportMetabolic healthRespiratory

Chaga · 2021 · Review · Polymers

Recent Developments in Inonotus obliquus (Chaga mushroom) Polysaccharides: Isolation, Structural Characteristics, Biological Activities and Application.

Inonotus obliquus (Chaga mushroom) is a kind of medicine and health food widely used by folk in China, Russia, Korea, and some occidental countries. Among the extracts from Inonotus obliquus, Inonotus obliquus polysaccharide (IOPS) is supposed to be one of the major bioactive components in Inonotus obliquus, which….

Reishi · 2021 · Review Article · Pharmaceutical biology

The beneficial effects of Ganoderma lucidum on cardiovascular and metabolic disease risk.

CONTEXT: Various herbal medicines are thought to be useful in the management of cardiometabolic disease and its risk factors. Ganoderma lucidum (Curtis) P.

OncologyImmune supportEnergy & fatigueMetabolic health

Cordyceps · 2019 · Clinical Trial · Oxidative medicine and cellular longevity

Cordyceps militaris Improves Chronic Kidney Disease by Affecting TLR4/NF-κB Redox Signaling Pathway.

Cordyceps militaris may show good promise in protecting against chronic kidney disease (CKD) but the molecular mechanism remains unclear. CKD risk is associated with the Toll-like receptor 4/nuclear factor-kappa B (TLR4/NF-κB) signaling pathway..

Almond Mushroom · 2012 · Randomized Controlled Trial · Scandinavian journal of immunology

Agaricus blazei Murrill and inflammatory mediators in elderly women: a randomized clinical trial.

There is scientific evidence to suggest that the medicinal mushroom Agaricus blazei Murrill (AbM) has immunomodulatory effects on cytokine synthesis, both in vitro and in vivo. This study was the first randomized, double-blind, placebo-controlled trial designed to investigate these purported actions in elderly women..

Maitake · 2010 · Randomized Controlled Trial · Journal of alternative and complementary medicine (New York, N.Y.)

Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate.

BACKGROUND: Insulin resistance is a prominent feature of polycystic ovary syndrome (PCOS), and insulin-sensitizing drugs are used to induce ovulation. Recently, it was reported that an extract from Maitake mushroom (Grifola frondosa) improves insulin resistance..

Oyster Mushroom · 2020 · Systematic Review · Nutrients

Effect of the Intake of Oyster Mushrooms (Pleurotus ostreatus) on Cardiometabolic Parameters-A Systematic Review of Clinical Trials.

Cardiometabolic diseases are a leading global health challenge. Their incidence as well as progression is strongly affected by diet.

OncologyImmune supportMetabolic healthLiver support

Reishi · 2025 · Journal Article · JPMA. The Journal of the Pakistan Medical Association

Therapeutic potential of Ganoderma lucidum/ Reishi mushroom.

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in JPMA. The Journal of the Pakistan Medical Association in 2025.

Cordyceps · 2024 · Journal Article · International journal of biological macromolecules

Elucidation of antioxidant activities of intracellular and extracellular polysaccharides from Cordyceps militaris in vitro and their protective effects on ulcerative colitis in vivo.

In this study, we extracted the polysaccharides from C. militaris fruiting bodies (CFIPs), mycelial intracellular polysaccharides (CMIPs), and fermentation broth extracellular polysaccharides (CFEPs) to investigate their physicochemical properties, antioxidant capacities, and effects on oxazolone-induced zebrafish….

OncologyImmune supportMetabolic healthLiver support

Mesima · 2023 · Systematic Review · International journal of biological macromolecules

Polysaccharides from Phellinus linteus: A systematic review of their extractions, purifications, structures and functions.

Phellinus linteus (P. linteus) is a famous Chinese medicine and has a long history in China.

OncologyImmune supportMetabolic healthGut & microbiome

Reishi · 2023 · Systematic Review · Food & function

Therapeutic potential and nutritional significance of Ganoderma lucidum - a comprehensive review from 2010 to 2022.

With a long history in traditional Asian medicine, Ganoderma lucidum (G. lucidum) is a mushroom species suggested to improve health and extend life.

OncologyImmune supportCognition & nervesMetabolic health

Lion's Mane · 2026 · Scoping Review · Chemistry & biodiversity

Hericenones From Hericium erinaceus (Bull.) Pers.: A Scoping Review of Structural Diversity and Health Benefits.

Hericium erinaceus (Bull.) Pers., an edible and medicinal mushroom, has garnered significant scientific interest due to its rich array of bioactive compounds. Extensive research has highlighted the pharmacological properties of its constituents, including neuroprotective, neurotrophic, immunomodulatory, and anticancer….

Reishi · 2025 · Review · International journal of biological macromolecules

A review of polysaccharides from Ganoderma lucidum: Preparation methods, structural characteristics, bioactivities, structure-activity relationships and potential applications.

Ganoderma lucidum (G. lucidum), commonly known as "fairy grass", is a saprophyte fungus belonging to the Polyporaceae family with a lengthy history of use as a food ingredient and traditional medicine in China.

OncologyImmune supportMetabolic healthGut & microbiome

Lion's Mane · 2025 · Review · Frontiers in nutrition

Advances in the extraction, purification, structural characterization, and elucidation of the biological functions of polysaccharides from Hericium erinaceus.

Hericium erinaceus has a high food and ornamental value and considerable benefits upon consumption and in research. The high polysaccharide content in H.

Niu-Chang-Chih · 2025 · Review · ACS omega

Biological Functions and Synthesis of the Active Components in Antrodia camphorata.

As a fungus endemic to Taiwan, Antrodia camphorata contains a variety of medicinally active substances, such as polysaccharides, triterpenoids, maleic acid and succinic acid derivatives, and ubiquinone derivatives. A..

Energy & fatigueMetabolic healthGut & microbiomeSkin & hydration

Shiitake · 2025 · Review · Applied microbiology and biotechnology

Cultivation methods and biology of Lentinula edodes.

In this study, the biological applications of cultivation methods related to cultivar selection, vegetative growth, and reproductive development in Lentinula edodes cultivation are briefly reviewed to clarify the current situation and inform future developments..

Lion's Mane · 2025 · Review · Food science & nutrition

Extraction, Structural Characterization and Biological Activities of Polysaccharides Derived From Hericium erinaceus.

Hericium erinaceus is acknowledged for its dual roles in medicinal and culinary contexts. The polysaccharides derived from H.

Immune supportEnergy & fatigueMetabolic health

Yellow Morel · 2025 · Review · Natural product research

Morchella esculenta polysaccharides: a functional food with potential immunomodulatory properties.

Modern pharmacological research has demonstrated highly appreciated culinary mushrooms, Morchella esculenta. The soluble β glucans are immunostimulatory that is mediated through production of proinflammatory cytokines and activation of nuclear factor-kappa B (NF-κB), leading to phagocytosis and resident macrophage….

OncologyImmune supportCognition & nervesMetabolic health

Snow Fungus · 2025 · Review · Journal of food science

Structure, Function and Application of Tremella Fuciformis Polysaccharide: A Review.

Tremella fuciformis (TF) is a valuable edible fungus rich in various nutrients, with TF polysaccharide (TFP) as its primary bioactive component. Extensive studies have demonstrated that TFP exhibits significant bioactivities, including antioxidant, antitumor, immunomodulatory, memory-enhancing, anti-inflammatory,….

OncologyImmune supportMetabolic healthGut & microbiome

Almond Mushroom · 2024 · Review · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Research progress on structures, activities, and biosynthesis of blazeispirol compounds from Agaricus blazei].

Agaricus blazei is a rare medicinal and edible fungus with a crispy taste and delicious flavor. Both fruiting body and mycelium are rich in polysaccharides, sterols, terpenoids, peptides, lipids, polyphenols, and other active ingredients, which have strong pharmacological activities such as anti-tumor, lipid-lowering,….

OncologyImmune supportMetabolic healthRespiratory

Chaga · 2024 · Review · Fungal biology and biotechnology

A review on the cultivation, bioactive compounds, health-promoting factors and clinical trials of medicinal mushrooms Taiwanofungus camphoratus, Inonotus obliquus and Tropicoporus linteus.

Medicinal mushrooms, such as Taiwanofungus camphoratus, Inonotus obliquus, and Tropicoporus linteus, have been used in traditional medicine for therapeutic purposes and promotion of overall health in China and many East Asian countries for centuries..

OncologyImmune supportCognition & nervesMetabolic health

Reishi · 2024 · Review · Chinese herbal medicines

Bioactive components, pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil: A review.

Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment. G.

OncologyImmune supportMetabolic healthGut & microbiome

Reishi · 2024 · Review · Heliyon

Bioactivities and industrial standardization status of Ganoderma lucidum: A comprehensive review.

Ganoderma lucidum (GL) is a potent source of bioactive compounds with diverse nutritional and pharmacological benefits. Its popularity as a dietary supplement, herbal remedy, and wellness product is steadily on the rise..

Reishi · 2024 · Review · Trends in biotechnology

Developing Ganoderma lucidum as a next-generation cell factory for food and nutraceuticals.

Ganoderma lucidum holds a colossal reservoir of hydrolytic enzymes and therapeutic compounds and can be a sustainable source of proteins and bioactive compounds. Its metabolic versatility, propelled by its rich genome content, provides excellent biosynthetic machinery for innovation-driven pathway engineering..

Reishi · 2024 · Review · The Journal of pharmacy and pharmacology

Ganoderma lucidum triterpenoids investigating their role in medicinal applications and genomic protection.

OBJECTIVES: Ganoderma lucidum (GL) is a white rot fungus widely used for its pharmacological properties and health benefits. GL consists of several biological components, including polysaccharides, sterols, and triterpenoids..

Reishi · 2024 · Review · Heliyon

Ganoderma lucidum: Insight into antimicrobial and antioxidant properties with development of secondary metabolites.

Ganoderma lucidum is a versatile mushroom. Polysaccharides and triterpenoids are the major bioactive compounds and have been used as traditional medicinal mushrooms since ancient times.

Reishi · 2024 · Review · International journal of biological macromolecules

Ganoderma lucidum: Multifaceted mechanisms to combat diabetes through polysaccharides and triterpenoids: A comprehensive review.

Diabetes is a chronic metabolic disorder. Diabetes complications can affect many organs and systems in the body.

OncologyImmune supportMetabolic healthGut & microbiome

Mesima · 2024 · Review · International journal of biological macromolecules

Phellinus linteus polysaccharides: A review on their preparation, structure-activity relationships, and drug delivery systems.

Phellinus linteus polysaccharides exhibit antitumor, immunomodulatory, anti-inflammatory, and antioxidant properties, mitigate insulin resistance, and enhance the diversity and abundance of gut microbiota. However, the bioactivities of P..

Reishi · 2024 · Review · Frontiers in microbiology

Regulatory effect of Ganoderma lucidum and its active components on gut flora in diseases.

Driven by the good developmental potential and favorable environment at this stage, Ganoderma lucidum is recognized as a precious large fungus with medicinal and nutritional health care values. Among them, polysaccharides, triterpenoids, oligosaccharides, trace elements, etc.

Metabolic healthSkin & hydration

Cordyceps · 2025 · Randomized Controlled Trial · Journal of cosmetic dermatology

Effect of a New Skin-Lightening Cosmetic Containing Cordyceps Extract in the Treatment of Melasma: A Clinical Trial.

BACKGROUND: Cordyceps is a valuable Chinese herbal medicine known for its various components with antioxidant properties, which may theoretically improve melasma..

Cordyceps · 2024 · Review · Journal of integrative medicine

Cordyceps as potential therapeutic agents for atherosclerosis.

Atherosclerosis is a leading cause of mortality and morbidity worldwide. Despite the challenges in managing atherosclerosis, researchers continue to investigate new treatments and complementary therapies..